{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T02:13:35Z","timestamp":1788315215295,"version":"build-2803163510"},"reference-count":20,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2026,5,29]],"date-time":"2026-05-29T00:00:00Z","timestamp":1780012800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,5,29]],"date-time":"2026-05-29T00:00:00Z","timestamp":1780012800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100010269","name":"Wellcome Trust","doi-asserted-by":"publisher","award":["106680\/Z\/14\/Z"],"award-info":[{"award-number":["106680\/Z\/14\/Z"]}],"id":[{"id":"10.13039\/100010269","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Tropical Med Int Health"],"published-print":{"date-parts":[[2026,9]]},"abstract":"ABSTRACT<\/jats:title>\n \n Objectives<\/jats:title>\n To describe the aetiology and antibiotic susceptibility patterns of common bacterial infections in hospitalised patients in Jakarta, Indonesia.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n \n We conducted a hospital\u2010wide point prevalence survey in six hospitals in 2019, capturing data from routinely ordered bacterial cultures taken before the start of antibiotic treatment. We report relevant bacteria\u2010antibiotic combinations for\n \n Escherichia coli<\/jats:italic>\n <\/jats:styled-content>\n and the ESKAPE group of pathogens.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n A total of 562 patients (52% women, median age 46\u2009years) were diagnosed with 587 infections, comprising 414 community\u2010acquired and 173 hospital\u2010acquired infections, with pneumonia most frequent (258, 44%). From 615 samples collected, 279 (45%) bacterial isolates were identified, of which 213 (76%) gram\u2010negative, including\n \n Klebsiella pneumoniae<\/jats:italic>\n <\/jats:styled-content>\n (68, 24%),\n \n Escherichia coli<\/jats:italic>\n <\/jats:styled-content>\n (37, 13%) and\n \n Pseudomonas aeruginosa<\/jats:italic>\n <\/jats:styled-content>\n (35, 13%) among others, and 66 (24%) gram\u2010positive, including\n \n Enterococcus faecalis<\/jats:italic>\n <\/jats:styled-content>\n (17, 6%) and\n \n Staphylococcus aureus<\/jats:italic>\n <\/jats:styled-content>\n (11, 4%) among others. Proportions of bacteria resistant to third\u2010generation cephalosporins (3GC) were 75% (47\/63) for\n \n Klebsiella pneumoniae<\/jats:italic>\n <\/jats:styled-content>\n , and 69\n %<\/jats:italic>\n (22\/32) for\n \n E. coli<\/jats:italic>\n <\/jats:styled-content>\n , and to carbapenems 64% (7\/11) for\n Acinetobacter<\/jats:italic>\n spp., 60% (3\/5) for\n Enterobacter<\/jats:italic>\n spp., 43% (3\/7) for\n \n E. coli<\/jats:styled-content>\n ,\n <\/jats:italic>\n 30% (7\/23) for\n \n P. aeruginosa<\/jats:italic>\n <\/jats:styled-content>\n and 29% (9\/31) for\n \n K. pneumoniae<\/jats:italic>\n <\/jats:styled-content>\n . Four of 11\u2009\n \n S.\u2009aureus<\/jats:italic>\n <\/jats:styled-content>\n isolates were methicillin\u2010resistant. A blood culture was done in only 52% (16\/31) of sepsis patients, and the results of positive blood cultures were reported after a median of 4\u2009days.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n This survey identified that a high proportion of common gram\u2010negative bacteria exhibited reduced susceptibility to first\u2010choice antibiotics and considerable underuse of bacterial cultures. These findings warrant enhanced infection prevention and control and antimicrobial stewardship.<\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/tmi.70162","type":"journal-article","created":{"date-parts":[[2026,5,29]],"date-time":"2026-05-29T12:49:01Z","timestamp":1780058941000},"page":"1231-1237","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Aetiology and Antibiotic Susceptibility of Common Bacterial Infections in Hospitalised Patients: A 2019 Multisite Cross\u2010Sectional Survey in Jakarta, Indonesia"],"prefix":"10.1111","volume":"31","author":[{"given":"Justin","family":"de Brabander","sequence":"first","affiliation":[{"name":"Faculty of Medicine Oxford University Clinical Research Unit Indonesia, Universitas Indonesia Jakarta Indonesia"},{"name":"Department of Internal Medicine, Division of Infectious Diseases Amsterdam UMC, University of Amsterdam Amsterdam the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erni J.","family":"Nelwan","sequence":"additional","affiliation":[{"name":"Faculty of Medicine Universitas Indonesia Jakarta Indonesia"},{"name":"Department of Internal Medicine, Division of Infectious Diseases Cipto Mangunkusumo National General Hospital Jakarta Indonesia"},{"name":"Infectious Disease and Immunology Research Cluster, Indonesian Medical Education and Research Institute Jakarta Indonesia"},{"name":"Metropolitan Medical Centre Hospital Jakarta Indonesia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ralalicia","family":"Limato","sequence":"additional","affiliation":[{"name":"Faculty of Medicine Oxford University Clinical Research Unit Indonesia, Universitas Indonesia Jakarta Indonesia"},{"name":"Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine University of Oxford Oxford UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Monik","family":"Alamanda","sequence":"additional","affiliation":[{"name":"Faculty of Medicine Oxford University Clinical Research Unit Indonesia, Universitas Indonesia Jakarta Indonesia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manzilina","family":"Mudia","sequence":"additional","affiliation":[{"name":"Faculty of Medicine Oxford University Clinical Research Unit Indonesia, Universitas Indonesia Jakarta Indonesia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Enty","family":"Tjoa","sequence":"additional","affiliation":[{"name":"Royal Taruma Hospital Jakarta Indonesia"},{"name":"School of Medicine and Health Sciences, Atma Jaya Catholic University Jakarta Indonesia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ifael Y.","family":"Mauleti","sequence":"additional","affiliation":[{"name":"Fatmawati General Hospital Jakarta Indonesia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Mayasari","sequence":"additional","affiliation":[{"name":"St. Carolus Hospital Jakarta Indonesia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Iman","family":"Firmansyah","sequence":"additional","affiliation":[{"name":"Prof. Dr. Sulianti Saroso Infectious Disease Hospital Jakarta Indonesia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T. 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