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A multinomial mixed logistic regression model analysed factors linked to seroprevalent cases, with descriptive analyses of seroincident cases.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Concomitant seroprevalence against\n                      <jats:italic>Rickettsia<\/jats:italic>\n                      and\n                      <jats:italic>Leptospira<\/jats:italic>\n                      was 9.38% (95% CI: 6.08%\u201313.37%). Associated factors included age (ORa\u2009=\u20091.02; 95% CI 1.007\u20131.03), male gender (ORa\u2009=\u20093.06; 95% CI: 1.75\u20135.37), fever history (ORa\u2009=\u20091.71; 95% CI: 1.06\u20132.77), presence of breeding pigs (ORa\u2009=\u20092.29; 95% CI 1.36\u20133.88), peridomicile yucca crops (ORa\u2009=\u20092.5; 95% CI 1.1\u20135.62), and deforestation practices (ORa\u2009=\u20091.74; 95% CI 1.06\u20132.87). Concomitant seroincidence was 1.09% (3\/274) (95% CI: 0.29%\u20134.05%). All seroincident cases were female, median age 31.83\u2009years (IQR: 8.69\u201356.99), with similar housing characteristics (soil floors, wooden walls, zinc roofs) and exposure to domestic and synanthropic animals.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>There is evidence of concomitant seroprevalent and seroincident cases against both microorganisms in rural Urab\u00e1, Colombia. These findings can improve public health surveillance systems in preventing, detecting, and managing clinical cases caused by these pathogens.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/tmi.70200","type":"journal-article","created":{"date-parts":[[2026,7,6]],"date-time":"2026-07-06T00:57:53Z","timestamp":1783299473000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Eco\u2010Epidemiological Study of Seropositivity Against\n                    <i>Rickettsia<\/i>\n                    and\n                    <i>Leptospira<\/i>\n                    Agents in Rural Areas of Urab\u00e1, Colombia"],"prefix":"10.1111","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0741-8528","authenticated-orcid":false,"given":"Mariana","family":"Torres\u2010Bustamante","sequence":"first","affiliation":[{"name":"Grupo Epidemiolog\u00eda Universidad de Antioquia  Medell\u00edn 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