{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T18:46:58Z","timestamp":1791917218450,"version":"4.3.4"},"reference-count":52,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2015,10,8]],"date-time":"2015-10-08T00:00:00Z","timestamp":1444262400000},"content-version":"vor","delay-in-days":7,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100004543","name":"China Scholarship Council","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004543","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Plant Journal"],"published-print":{"date-parts":[[2015,10]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>The molecular genetic mechanisms underlying fruit size remain poorly understood in perennial crops, despite size being an important agronomic trait. Here we show that the expression level of a<jats:italic>micro<jats:styled-content style=\"fixed-case\">RNA<\/jats:styled-content><\/jats:italic>gene (<jats:italic>mi<jats:styled-content style=\"fixed-case\">RNA<\/jats:styled-content>172<\/jats:italic>) influences fruit size in apple. A transposon insertional allele of<jats:italic>mi<jats:styled-content style=\"fixed-case\">RNA<\/jats:styled-content>172<\/jats:italic>showing reduced expression associates with large fruit in an apple breeding population, whereas over\u2010expression of<jats:italic>mi<jats:styled-content style=\"fixed-case\">RNA<\/jats:styled-content>172<\/jats:italic>in transgenic apple significantly reduces fruit size. The transposon insertional allele was found to be co\u2010located with a major fruit size quantitative trait locus, fixed in cultivated apples and their wild progenitor species with relatively large fruit. This finding supports the view that the selection for large size in apple fruit was initiated prior to apple domestication, likely by large mammals, before being subsequently strengthened by humans, and also helps to explain why signatures of genetic bottlenecks and selective sweeps are normally weaker in perennial crops than in annual crops.<\/jats:p>","DOI":"10.1111\/tpj.13021","type":"journal-article","created":{"date-parts":[[2015,9,11]],"date-time":"2015-09-11T05:10:54Z","timestamp":1441948254000},"page":"417-427","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":118,"title":["A<i>micro<scp>RNA<\/scp><\/i>allele that emerged prior to apple domestication may underlie fruit size evolution"],"prefix":"10.1111","volume":"84","author":[{"given":"Jia\u2010Long","family":"Yao","sequence":"first","affiliation":[{"name":"The New Zealand Institute for Plant &amp; Food Research Limited Private Bag 92169 Auckland 1142 New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan","family":"Xu","sequence":"additional","affiliation":[{"name":"The New Zealand Institute for Plant &amp; 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