{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T01:56:02Z","timestamp":1792461362142,"version":"4.5.0"},"reference-count":124,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2022,4,8]],"date-time":"2022-04-08T00:00:00Z","timestamp":1649376000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["HO1916\/13\u20101"],"award-info":[{"award-number":["HO1916\/13\u20101"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004189","name":"Max-Planck-Gesellschaft","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004189","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Plant Journal"],"published-print":{"date-parts":[[2022,6]]},"abstract":"<jats:title>SUMMARY<\/jats:title><jats:p><jats:italic>Arabidopsis thaliana sulfur deficiency\u2010induced 1<\/jats:italic> and <jats:italic>sulfur deficiency\u2010induced 2<\/jats:italic> (<jats:italic>SDI1<\/jats:italic> and <jats:italic>SDI2<\/jats:italic>) are involved in partitioning sulfur among metabolite pools during sulfur deficiency, and their transcript levels strongly increase in this condition. However, little is currently known about the <jats:italic>cis<\/jats:italic>\u2010 and <jats:italic>trans<\/jats:italic>\u2010factors that regulate <jats:italic>SDI<\/jats:italic> expression. We aimed at identifying DNA sequence elements (<jats:italic>cis\u2010<\/jats:italic>elements) and transcription factors (TFs) involved in regulating expression of the <jats:italic>SDI<\/jats:italic> genes. We performed <jats:italic>in silico<\/jats:italic> analysis of their promoter sequences cataloging known <jats:italic>cis<\/jats:italic>\u2010elements and identifying conserved sequence motifs. We screened by yeast\u2010one\u2010hybrid an arrayed library of Arabidopsis TFs for binding to the <jats:italic>SDI1<\/jats:italic> and <jats:italic>SDI2<\/jats:italic> promoters. In total, 14 candidate TFs were identified. Direct association between particular <jats:italic>cis<\/jats:italic>\u2010elements in the proximal <jats:italic>SDI<\/jats:italic> promoter regions and specific TFs was established via electrophoretic mobility shift assays: sulfur limitation 1 (SLIM1) was shown to bind SURE <jats:italic>cis<\/jats:italic>\u2010element(s), the basic domain\/leucine zipper (bZIP) core <jats:italic>cis<\/jats:italic>\u2010element was shown to be important for HY5\u2010homolog (HYH) binding, and G\u2010box binding factor 1 (GBF1) was shown to bind the E box. Functional analysis of GBF1 and HYH using mutant and over\u2010expressing lines indicated that these TFs promote a higher transcript level of <jats:italic>SDI1 in\u2009vivo<\/jats:italic>. Additionally, we performed a meta\u2010analysis of expression changes of the 14 TF candidates in a variety of conditions that alter <jats:italic>SDI<\/jats:italic> expression. The presented results expand our understanding of sulfur pool regulation by <jats:italic>SDI<\/jats:italic> genes.<\/jats:p>","DOI":"10.1111\/tpj.15735","type":"journal-article","created":{"date-parts":[[2022,3,22]],"date-time":"2022-03-22T02:39:41Z","timestamp":1647916781000},"page":"1286-1304","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["<i>In silico<\/i> analysis of <i>cis<\/i>\u2010elements and identification of transcription factors putatively involved in the regulation of the <scp>OAS<\/scp> cluster genes <scp><i>SDI1<\/i><\/scp> and <scp><i>SDI2<\/i><\/scp>"],"prefix":"10.1111","volume":"110","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9946-5788","authenticated-orcid":false,"given":"Apidet","family":"Rakpenthai","sequence":"first","affiliation":[{"name":"Max Planck Institute of Molecular Plant Physiology  Am M\u00fchlenberg 1 14476 Potsdam\u2010Golm Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9309-5608","authenticated-orcid":false,"given":"Anastasia","family":"Apodiakou","sequence":"additional","affiliation":[{"name":"Max Planck Institute of Molecular Plant Physiology  Am M\u00fchlenberg 1 14476 Potsdam\u2010Golm Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1392-1496","authenticated-orcid":false,"given":"Sarah J.","family":"Whitcomb","sequence":"additional","affiliation":[{"name":"Max Planck Institute of Molecular Plant Physiology  Am M\u00fchlenberg 1 14476 Potsdam\u2010Golm Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8590-9800","authenticated-orcid":false,"given":"Rainer","family":"Hoefgen","sequence":"additional","affiliation":[{"name":"Max Planck Institute of Molecular Plant Physiology  Am M\u00fchlenberg 1 14476 Potsdam\u2010Golm Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,4,8]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"crossref","unstructured":"Aarabi F. Hubberten H.M. Heyneke E. Watanabe M.&Hoefgen R.(2015)OAS cluster genes: a tightly co\u2010regulated network. InProceedings of the International Plant Sulfur Workshop pp.125\u2013132.","DOI":"10.1007\/978-3-319-20137-5_13"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.1601087"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tplants.2020.07.007"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/plphys\/kiab386"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1105\/tpc.9.10.1859"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpls.2014.00704"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gky964"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkp335"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1105\/tpc.021147"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1038\/msb.2013.40"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkl887"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpls.2014.00805"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2016.09.015"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2199-12-33"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-313X.2011.04640.x"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0021524"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1093\/jxb\/erz119"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1105\/tpc.010410"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.4161\/psb.5.8.12231"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4939-6396-6_17"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2105-4-25"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1105\/tpc.110.073957"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1104\/pp.20.01192"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1128\/MCB.00459-07"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0014101"},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2007-965431"},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.1093\/jxb\/ern144"},{"key":"e_1_2_9_29_1","doi-asserted-by":"publisher","DOI":"10.1111\/pce.12842"},{"key":"e_1_2_9_30_1","doi-asserted-by":"publisher","DOI":"10.1038\/82822"},{"key":"e_1_2_9_31_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00020166"},{"key":"e_1_2_9_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.febslet.2008.02.037"},{"key":"e_1_2_9_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.molp.2016.06.003"},{"key":"e_1_2_9_34_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature10534"},{"key":"e_1_2_9_35_1","doi-asserted-by":"publisher","DOI":"10.1093\/mp\/ssu042"},{"key":"e_1_2_9_36_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-313X.2008.03510.x"},{"key":"e_1_2_9_37_1","doi-asserted-by":"publisher","DOI":"10.1104\/pp.103.034736"},{"key":"e_1_2_9_38_1","doi-asserted-by":"publisher","DOI":"10.1104\/pp.111.177766"},{"key":"e_1_2_9_39_1","doi-asserted-by":"publisher","DOI":"10.1111\/tpj.12194"},{"key":"e_1_2_9_40_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1522-2683(19990101)20:4\/5<826::AID-ELPS826>3.0.CO;2-A"},{"key":"e_1_2_9_41_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-313X.2003.01658.x"},{"key":"e_1_2_9_42_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-3054.2007.01012.x"},{"key":"e_1_2_9_43_1","doi-asserted-by":"publisher","DOI":"10.1101\/gad.969702"},{"key":"e_1_2_9_44_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1467-7652.2008.00391.x"},{"key":"e_1_2_9_45_1","doi-asserted-by":"publisher","DOI":"10.1105\/tpc.112.105478"},{"key":"e_1_2_9_46_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-313X.2012.04905.x"},{"key":"e_1_2_9_47_1","doi-asserted-by":"publisher","DOI":"10.1104\/pp.103.030437"},{"key":"e_1_2_9_48_1","doi-asserted-by":"publisher","DOI":"10.1111\/tpj.12162"},{"key":"e_1_2_9_49_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.devcel.2011.09.009"},{"key":"e_1_2_9_50_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1360-1385(01)02223-3"},{"key":"e_1_2_9_51_1","doi-asserted-by":"publisher","DOI":"10.1105\/tpc.105.035840"},{"key":"e_1_2_9_52_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-313X.2012.04924.x"},{"key":"e_1_2_9_53_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/27.2.470"},{"key":"e_1_2_9_54_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-313X.2011.04547.x"},{"key":"e_1_2_9_55_1","doi-asserted-by":"publisher","DOI":"10.1007\/s004250050634"},{"key":"e_1_2_9_56_1","doi-asserted-by":"publisher","DOI":"10.1104\/pp.18.01471"},{"key":"e_1_2_9_57_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-313X.1997.11061237.x"},{"key":"e_1_2_9_58_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cub.2011.04.045"},{"key":"e_1_2_9_59_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11103-012-9880-7"},{"key":"e_1_2_9_60_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1747-0765.2006.00025.x"},{"key":"e_1_2_9_61_1","doi-asserted-by":"publisher","DOI":"10.1093\/jxb\/erz319"},{"key":"e_1_2_9_62_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/28.4.960"},{"key":"e_1_2_9_63_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.129.9.2079"},{"key":"e_1_2_9_64_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-313X.2011.04656.x"},{"key":"e_1_2_9_65_1","doi-asserted-by":"publisher","DOI":"10.1093\/mp\/ssn080"},{"key":"e_1_2_9_66_1","doi-asserted-by":"publisher","DOI":"10.18388\/abp.2008_3051"},{"key":"e_1_2_9_67_1","doi-asserted-by":"publisher","DOI":"10.1093\/mp\/ssq007"},{"key":"e_1_2_9_68_1","doi-asserted-by":"publisher","DOI":"10.1105\/tpc.113.114868"},{"key":"e_1_2_9_69_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-313X.2010.04149.x"},{"key":"e_1_2_9_70_1","doi-asserted-by":"publisher","DOI":"10.1006\/meth.1993.1017"},{"key":"e_1_2_9_71_1","doi-asserted-by":"publisher","DOI":"10.1104\/pp.108.117408"},{"key":"e_1_2_9_72_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-313X.1998.00259.x"},{"key":"e_1_2_9_73_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M601172200"},{"key":"e_1_2_9_74_1","doi-asserted-by":"publisher","DOI":"10.1021\/es404958r"},{"key":"e_1_2_9_75_1","doi-asserted-by":"publisher","DOI":"10.1105\/tpc.007609"},{"key":"e_1_2_9_76_1","doi-asserted-by":"publisher","DOI":"10.1104\/pp.102.019802"},{"key":"e_1_2_9_77_1","doi-asserted-by":"publisher","DOI":"10.1105\/tpc.106.046458"},{"key":"e_1_2_9_78_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-313X.2005.02363.x"},{"key":"e_1_2_9_79_1","doi-asserted-by":"publisher","DOI":"10.1093\/jxb\/erh175"},{"key":"e_1_2_9_80_1","doi-asserted-by":"publisher","DOI":"10.1111\/tpj.12899"},{"key":"e_1_2_9_81_1","doi-asserted-by":"publisher","DOI":"10.1093\/pcp\/pcq041"},{"key":"e_1_2_9_82_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11103-005-2418-5"},{"key":"e_1_2_9_83_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13059-017-1302-3"},{"key":"e_1_2_9_84_1","doi-asserted-by":"publisher","DOI":"10.1104\/pp.111.183129"},{"key":"e_1_2_9_85_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-313X.2003.01657.x"},{"key":"e_1_2_9_86_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-291X(02)03019-X"},{"key":"e_1_2_9_87_1","doi-asserted-by":"publisher","DOI":"10.1093\/pcp\/pcf183"},{"key":"e_1_2_9_88_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2016.04.038"},{"key":"e_1_2_9_89_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0711203105"},{"key":"e_1_2_9_90_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkp805"},{"key":"e_1_2_9_91_1","doi-asserted-by":"publisher","DOI":"10.1105\/tpc.106.045898"},{"key":"e_1_2_9_92_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1302170110"},{"key":"e_1_2_9_93_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1369-5266(00)00063-7"},{"key":"e_1_2_9_94_1","doi-asserted-by":"publisher","DOI":"10.1104\/pp.104.046755"},{"key":"e_1_2_9_95_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11103-007-9274-4"},{"key":"e_1_2_9_96_1","doi-asserted-by":"publisher","DOI":"10.1038\/nprot.2008.73"},{"key":"e_1_2_9_97_1","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btt663"},{"key":"e_1_2_9_98_1","doi-asserted-by":"publisher","DOI":"10.1105\/tpc.113.117390"},{"key":"e_1_2_9_99_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00425-013-1940-y"},{"key":"e_1_2_9_100_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-313X.2003.01624.x"},{"key":"e_1_2_9_101_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00195181"},{"key":"e_1_2_9_102_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.201413498"},{"key":"e_1_2_9_103_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-arplant-042110-103921"},{"key":"e_1_2_9_104_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tibtech.2018.12.002"},{"key":"e_1_2_9_105_1","doi-asserted-by":"publisher","DOI":"10.1126\/scisignal.2003509"},{"key":"e_1_2_9_106_1","doi-asserted-by":"publisher","DOI":"10.4161\/psb.21664"},{"key":"e_1_2_9_107_1","doi-asserted-by":"publisher","DOI":"10.1104\/pp.113.215996"},{"key":"e_1_2_9_108_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkx1002"},{"key":"e_1_2_9_109_1","doi-asserted-by":"publisher","DOI":"10.1093\/aob\/mcn126"},{"key":"e_1_2_9_110_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-3054.2007.01002.x"},{"key":"e_1_2_9_111_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpls.2015.00809"},{"key":"e_1_2_9_112_1","doi-asserted-by":"publisher","DOI":"10.1186\/gb-2011-12-4-109"},{"key":"e_1_2_9_113_1","doi-asserted-by":"publisher","DOI":"10.1093\/jxb\/erz260"},{"key":"e_1_2_9_114_1","doi-asserted-by":"publisher","DOI":"10.1093\/jxb\/erp356"},{"key":"e_1_2_9_115_1","doi-asserted-by":"publisher","DOI":"10.1105\/tpc.4.4.485"},{"key":"e_1_2_9_116_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmb.2005.02.065"},{"key":"e_1_2_9_117_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gki368"},{"key":"e_1_2_9_118_1","doi-asserted-by":"publisher","DOI":"10.1104\/pp.111.172486"},{"key":"e_1_2_9_119_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M207941200"},{"key":"e_1_2_9_120_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-313X.2009.04118.x"},{"key":"e_1_2_9_121_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkq1120"},{"key":"e_1_2_9_122_1","doi-asserted-by":"publisher","DOI":"10.1038\/srep37004"},{"key":"e_1_2_9_123_1","doi-asserted-by":"publisher","DOI":"10.1105\/TPC.010115"},{"key":"e_1_2_9_124_1","doi-asserted-by":"publisher","DOI":"10.1002\/jsfa.2740640309"},{"key":"e_1_2_9_125_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tplants.2005.07.003"}],"container-title":["The Plant Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/tpj.15735","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/tpj.15735","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/tpj.15735","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,24]],"date-time":"2023-08-24T12:22:06Z","timestamp":1692879726000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/tpj.15735"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,4,8]]},"references-count":124,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2022,6]]}},"alternative-id":["10.1111\/tpj.15735"],"URL":"https:\/\/doi.org\/10.1111\/tpj.15735","archive":["Portico"],"relation":{},"ISSN":["0960-7412","1365-313X"],"issn-type":[{"value":"0960-7412","type":"print"},{"value":"1365-313X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,4,8]]},"assertion":[{"value":"2021-03-30","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-03-01","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-04-08","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}