{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T15:17:18Z","timestamp":1791213438039,"version":"4.1.0"},"reference-count":56,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2022,10,21]],"date-time":"2022-10-21T00:00:00Z","timestamp":1666310400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100005688","name":"Graduate School, University of Texas, Austin","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100005688","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Plant Journal"],"published-print":{"date-parts":[[2022,11]]},"abstract":"<jats:title>SUMMARY<\/jats:title>\n                  <jats:p>\n                    Infections by root\u2010feeding nematodes have profound effects on root system architecture and consequently shoot growth of host plants. Plants harbor intraspecific variation in their growth responses to belowground biotic stresses by nematodes, but the underlying mechanisms are not well understood. Here, we show that the transcription factor TEOSINTE BRANCHED\/CYCLOIDEA\/PROLIFERATING CELL FACTOR\u20109 (TCP9) modulates root system architectural plasticity in\n                    <jats:italic>Arabidopsis thaliana<\/jats:italic>\n                    in response to infections by the endoparasitic cyst nematode\n                    <jats:italic>Heterodera schachtii<\/jats:italic>\n                    . Young seedlings of\n                    <jats:italic>tcp9<\/jats:italic>\n                    knock\u2010out mutants display a significantly weaker primary root growth inhibition response to cyst nematodes than wild\u2010type Arabidopsis. In older plants,\n                    <jats:italic>tcp9<\/jats:italic>\n                    reduces the impact of nematode infections on the emergence and growth of secondary roots. Importantly, the altered growth responses by\n                    <jats:italic>tcp9<\/jats:italic>\n                    are most likely not caused by less biotic stress on the root system, because TCP9 does not affect the number of infections, nematode development, and size of the nematode\u2010induced feeding structures. RNA\u2010sequencing of nematode\u2010infected roots of the\n                    <jats:italic>tcp9<\/jats:italic>\n                    mutants revealed differential regulation of enzymes involved in reactive oxygen species (ROS) homeostasis and responses to oxidative stress. We also found that root and shoot growth of\n                    <jats:italic>tcp9<\/jats:italic>\n                    mutants is less sensitive to exogenous hydrogen peroxide and that ROS accumulation in nematode infection sites in these mutants is reduced. Altogether, these observations demonstrate that TCP9 modulates the root system architectural plasticity to nematode infections via ROS\u2010mediated processes. Our study further points at a novel regulatory mechanism contributing to the tolerance of plants to root\u2010feeding nematodes by mitigating the impact of belowground biotic stresses.\n                  <\/jats:p>","DOI":"10.1111\/tpj.15996","type":"journal-article","created":{"date-parts":[[2022,10,1]],"date-time":"2022-10-01T14:04:58Z","timestamp":1664633098000},"page":"1070-1083","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":25,"title":["The Arabidopsis transcription factor\n                    <scp>TCP9<\/scp>\n                    modulates root architectural plasticity, reactive oxygen species\u2010mediated processes, and tolerance to cyst nematode infections"],"prefix":"10.1111","volume":"112","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1872-1300","authenticated-orcid":false,"given":"Jaap\u2010Jan","family":"Willig","sequence":"first","affiliation":[{"name":"Laboratory of Nematology Wageningen University &amp; Research 6708PB Wageningen The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0399-9230","authenticated-orcid":false,"given":"Nina","family":"Guarneri","sequence":"additional","affiliation":[{"name":"Laboratory of Nematology Wageningen University &amp; Research 6708PB Wageningen The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9961-2538","authenticated-orcid":false,"given":"Joris J. M.","family":"van Steenbrugge","sequence":"additional","affiliation":[{"name":"Laboratory of Nematology Wageningen University &amp; Research 6708PB Wageningen The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Willem","family":"de Jong","sequence":"additional","affiliation":[{"name":"Laboratory of Nematology Wageningen University &amp; Research 6708PB Wageningen The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jingrong","family":"Chen","sequence":"additional","affiliation":[{"name":"Laboratory of Nematology Wageningen University &amp; Research 6708PB Wageningen The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7399-8743","authenticated-orcid":false,"given":"Aska","family":"Goverse","sequence":"additional","affiliation":[{"name":"Laboratory of Nematology Wageningen University &amp; Research 6708PB Wageningen The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0021-5947","authenticated-orcid":false,"given":"Jos\u00e9 L.","family":"Lozano Torres","sequence":"additional","affiliation":[{"name":"Laboratory of Nematology Wageningen University &amp; Research 6708PB Wageningen The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7119-6213","authenticated-orcid":false,"given":"Mark G.","family":"Sterken","sequence":"additional","affiliation":[{"name":"Laboratory of Nematology Wageningen University &amp; Research 6708PB Wageningen The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jaap","family":"Bakker","sequence":"additional","affiliation":[{"name":"Laboratory of Nematology Wageningen University &amp; Research 6708PB Wageningen The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6094-8686","authenticated-orcid":false,"given":"Geert","family":"Smant","sequence":"additional","affiliation":[{"name":"Laboratory of Nematology Wageningen University &amp; Research 6708PB Wageningen The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,10,21]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11103\u2010021\u201001227\u20108"},{"key":"e_1_2_9_3_1","first-page":"166","article-title":"A screen for Arabidopsis thaliana mutants with altered susceptibility to Heterodera schachtii","volume":"32","author":"Baum T.J.","year":"2000","journal-title":"Journal of Nematology"},{"issue":"1","key":"e_1_2_9_4_1","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1111\/j.2517-6161.1995.tb02031.x","article-title":"Controlling the false discovery rate: a practical and powerful approach to multiple testing author ( s ): Yoav Benjamini and Yosef Hochberg source","volume":"57","author":"Benjamini Y.","year":"1995","journal-title":"Journal of the Royal Statistical Society. 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