{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T23:29:53Z","timestamp":1782948593912,"version":"3.54.5"},"reference-count":61,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2025,3,3]],"date-time":"2025-03-03T00:00:00Z","timestamp":1740960000000},"content-version":"vor","delay-in-days":2,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["160\/620\u20101"],"award-info":[{"award-number":["160\/620\u20101"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Plant Journal"],"published-print":{"date-parts":[[2025,3]]},"abstract":"<jats:title>SUMMARY<\/jats:title>\n                  <jats:p>\n                    <jats:italic>Sarcandra glabra<\/jats:italic>\n                    (Chloranthaceae) has an elaborate phenolic metabolism, encompassing various hydroxycinnamic acid esters. This may imply that multiple hydroxycinnamoyltransferases are involved in establishing this spectrum of natural compounds. Five coding sequences from\n                    <jats:italic>S. glabra<\/jats:italic>\n                    , belonging to the superfamily of BAHD acyltransferases, have been amplified from\n                    <jats:italic>S. glabra<\/jats:italic>\n                    cDNA, and the proteins were expressed in\n                    <jats:italic>Escherichia coli<\/jats:italic>\n                    . By assaying the proteins biochemically, the main substrates of these enzymes were identified as\n                    <jats:italic>p<\/jats:italic>\n                    \u2010coumaroyl\u2010 and caffeoyl\u2010CoA as donor substrates together with varying acceptor substrates. SgHST mainly forms\n                    <jats:italic>p<\/jats:italic>\n                    \u2010coumaroyl\u2010 and caffeoylshikimic acid, but also the corresponding quinic acid esters as well as amides with 3\u2010 and 5\u2010hydroxyanthranilic acids. SgHQT1 predominantly catalyzes the formation of\n                    <jats:italic>p<\/jats:italic>\n                    \u2010coumaroyl\u2010 and caffeoyl\u20105\u2010\n                    <jats:italic>O<\/jats:italic>\n                    \u2010quinic acid, while SgHQT2 correspondingly forms\n                    <jats:italic>p<\/jats:italic>\n                    \u2010coumaroyl\u2010 and caffeoyl\u20104\u2010\n                    <jats:italic>O<\/jats:italic>\n                    \u2010quinic acid. To our knowledge, this is the first characterized enzyme forming cryptochlorogenic acid and its precursor\n                    <jats:italic>p<\/jats:italic>\n                    \u2010coumaroyl\u20104\u2010\n                    <jats:italic>O<\/jats:italic>\n                    \u2010quinic acid. SgRAS synthesizes rosmarinic acid and its precursors (caffeoyl\u20104\u2032\u2010hydroxyphenyllactic,\n                    <jats:italic>p<\/jats:italic>\n                    \u2010coumaroyl\u20104\u2032\u2010hydroxyphenyllactic,\n                    <jats:italic>p<\/jats:italic>\n                    \u2010coumaroyl\u20103\u2032,4\u2032\u2010dihydroxyphenyllactic acids) as well as amides with aromatic\n                    <jats:sc>d<\/jats:sc>\n                    \u2010amino acids. No substrates could be identified for the fifth sequence, SgHCT\u2010F, which phylogenetically groups with benzyl alcohol\n                    <jats:italic>O<\/jats:italic>\n                    \u2010benzoyltransferases. All enzymes, except SgHCT\u2010F, were fully kinetically characterized, and their expression in different tissues of\n                    <jats:italic>S. glabra<\/jats:italic>\n                    was assessed.\n                  <\/jats:p>","DOI":"10.1111\/tpj.70035","type":"journal-article","created":{"date-parts":[[2025,3,12]],"date-time":"2025-03-12T01:58:59Z","timestamp":1741744739000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Phenolic metabolism in\n                    <i>Sarcandra glabra<\/i>\n                    is mediated by distinct\n                    <scp>BAHD<\/scp>\n                    hydroxycinnamoyltransferases"],"prefix":"10.1111","volume":"121","author":[{"given":"Paul","family":"B\u00f6meke","sequence":"first","affiliation":[{"name":"Institut f\u00fcr Pharmazeutische Biologie und Biotechnologie Philipps\u2010Universit\u00e4t Marburg  Robert\u2010Koch\u2010Str. 4 Marburg 35037 Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7769-8556","authenticated-orcid":false,"given":"Maike","family":"Petersen","sequence":"additional","affiliation":[{"name":"Institut f\u00fcr Pharmazeutische Biologie und Biotechnologie Philipps\u2010Universit\u00e4t Marburg  Robert\u2010Koch\u2010Str. 4 Marburg 35037 Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,3,3]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/tpj.15390"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00425\u2010006\u20100393\u2010y"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1006\/abio.2001.5574"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0031\u20109422(00)86654\u20106"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/0003\u20102697(76)90527\u20103"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/gigascience\/giz126"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/0003\u20102697(87)90021\u20102"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13659\u2010023\u201000418\u20108"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1039\/C7NP00030H"},{"key":"e_1_2_8_11_1","first-page":"29","article-title":"Chemical 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