{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T16:18:18Z","timestamp":1779293898506,"version":"3.51.4"},"reference-count":43,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2026,1,17]],"date-time":"2026-01-17T00:00:00Z","timestamp":1768608000000},"content-version":"vor","delay-in-days":16,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2023YFF1001300"],"award-info":[{"award-number":["2023YFF1001300"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32270306"],"award-info":[{"award-number":["32270306"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Plant Journal"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:title>SUMMARY<\/jats:title>\n                  <jats:p>\n                    Drought and pathogen infection severely affect plant growth and development. The plant hormones abscisic acid and salicylic acid promote drought and disease resistance, respectively. However, it is largely unknown how plants balance these two stress responses. The salicylic acid receptor NPR1 is required for pathogen resistance and the transcription factors ABF3\/4 are required for drought resistance. Here, we show that NPR1 negatively regulates drought resistance by inhibiting ABF3\/4 in Arabidopsis. The\n                    <jats:italic>npr1<\/jats:italic>\n                    mutant is more resistant to drought stress than wild type. Transcriptome analysis reveals that the\n                    <jats:italic>npr1<\/jats:italic>\n                    mutant shows enhanced expression of the drought\u2010responsive genes, in which the ABF\u2010binding motif is significantly enriched. Genetically, loss of\n                    <jats:italic>ABF3\/4<\/jats:italic>\n                    suppresses the enhanced drought resistance of\n                    <jats:italic>npr1<\/jats:italic>\n                    . Biochemically, NPR1 physically interacts with ABF3\/4 and functions as the adaptor protein of the cullin3\u2010based E3 ubiquitin ligase CRL3\n                    <jats:sup>NPR1<\/jats:sup>\n                    to mediate the polyubiquitination and degradation of ABF3\/4. Therefore, our study suggests that NPR1 antagonistically regulates drought resistance and disease resistance.\n                  <\/jats:p>","DOI":"10.1111\/tpj.70676","type":"journal-article","created":{"date-parts":[[2026,1,17]],"date-time":"2026-01-17T20:09:42Z","timestamp":1768680582000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["The salicylic acid receptor\n                    <scp>NPR1<\/scp>\n                    mediates the polyubiquitination and degradation of the transcription factors\n                    <scp>ABF3<\/scp>\n                    \/4 to inhibit drought resistance"],"prefix":"10.1111","volume":"125","author":[{"given":"Chong","family":"Huang","sequence":"first","affiliation":[{"name":"Hubei Hongshan Laboratory, College of Life Science and Technology Huazhong Agricultural University  Wuhan 430070 China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaodan","family":"Yu","sequence":"additional","affiliation":[{"name":"Hubei Hongshan Laboratory, College of Life Science and Technology Huazhong Agricultural University  Wuhan 430070 China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhenjie","family":"Hu","sequence":"additional","affiliation":[{"name":"Hubei Hongshan Laboratory, College of Life Science and Technology Huazhong Agricultural University  Wuhan 430070 China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shunping","family":"Yan","sequence":"additional","affiliation":[{"name":"Hubei Hongshan Laboratory, College of Life Science and Technology Huazhong Agricultural University  Wuhan 430070 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