{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T11:05:24Z","timestamp":1789729524272,"version":"4.0.1"},"reference-count":62,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2026,9,13]],"date-time":"2026-09-13T00:00:00Z","timestamp":1789257600000},"content-version":"vor","delay-in-days":12,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2021YFD2200102"],"award-info":[{"award-number":["2021YFD2200102"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Plant Journal"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>SUMMARY<\/jats:title>\n                  <jats:p>\n                    Optimization of tree architecture is essential for advancing sustainable forestry, as appropriate canopy structure can contribute to growth and development. However, the molecular mechanisms that control tree architecture have not been fully characterized. While the putative NAD\u2010dependent histone deacetylase HST1 was shown to regulate branching architecture in multiple crop species, whether epigenetic mechanism also influence tree architecture is unknown. Here, we investigated the genetic regulation of branching angle in white birch (\n                    <jats:italic>Betula platyphylla<\/jats:italic>\n                    Suk.), a pioneer tree of the temperate and boreal forests. Using\n                    <jats:italic>bphst1<\/jats:italic>\n                    mutants generated via gene editing, we demonstrate that BpHST1 is involved in tree architecture by modulating branching angles. We provide evidence that BpHST1 is a histone deacetylase associated with altered H3K27ac levels and that it affects the expression of the cellulase gene\n                    <jats:italic>CELLULASE 1<\/jats:italic>\n                    (\n                    <jats:italic>BpCEL1<\/jats:italic>\n                    ). Compared with the wild type\n                    <jats:italic>, BpHST1<\/jats:italic>\n                    knockout and\n                    <jats:italic>BpCEL1<\/jats:italic>\n                    overexpression both resulted in reduced branch angles, supporting\n                    <jats:italic>BpCEL1<\/jats:italic>\n                    as a candidate downstream effector of BpHST1. Our study suggests that BpHST1 influences the birch architecture by altering H3K27 acetylation at the\n                    <jats:italic>BpCEL1<\/jats:italic>\n                    locus, elucidating a previously unknown aspect of the epigenetic mechanisms that control tree architecture in white birch.\n                  <\/jats:p>","DOI":"10.1111\/tpj.71116","type":"journal-article","created":{"date-parts":[[2026,9,13]],"date-time":"2026-09-13T15:52:31Z","timestamp":1789314751000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["The histone deacetylase\n                    <i>BpHST1<\/i>\n                    influences branch angle in white birch (\n                    <i>Betula platyphylla<\/i>\n                    )"],"prefix":"10.1111","volume":"127","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-6792-9013","authenticated-orcid":false,"given":"Lili","family":"Hou","sequence":"first","affiliation":[{"name":"State Key Laboratory of Tree Genetics and Breeding, College of Forestry Northeast Forestry University  Harbin 150040 China"},{"name":"The Center for Basic Forestry Research, College of Forestry Northeast Forestry University  Harbin 150040 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Baoxin","family":"Li","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Tree Genetics and Breeding, College of Forestry Northeast Forestry University  Harbin 150040 China"},{"name":"The Center for Basic Forestry Research, College of Forestry Northeast Forestry University  Harbin 150040 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yueying","family":"Liu","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Tree Genetics and Breeding, College of Forestry Northeast Forestry University  Harbin 150040 China"},{"name":"The Center for Basic Forestry Research, College of Forestry Northeast Forestry University  Harbin 150040 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8246-6688","authenticated-orcid":false,"given":"Qingzhu","family":"Zhang","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Tree Genetics and Breeding, College of Forestry Northeast Forestry University  Harbin 150040 China"},{"name":"The Center for Basic Forestry Research, College of Forestry Northeast Forestry University  Harbin 150040 China"},{"name":"School of Ecology Northeast Forestry University  Harbin China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2859-3066","authenticated-orcid":false,"given":"Zhimin","family":"Zheng","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Tree Genetics and Breeding, College of Forestry Northeast Forestry University  Harbin 150040 China"},{"name":"The Center for Basic Forestry Research, College of Forestry Northeast Forestry University  Harbin 150040 China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,9,13]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tifs.2024.104704"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gde.2011.01.017"},{"key":"e_1_2_9_4_1","first-page":"2183","article-title":"Targeting histone acetylation dynamics and oncogenic transcription by catalytic P300\/CBP inhibition","volume":"10","author":"Bromberg K.D.","year":"2021","journal-title":"Molecular 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