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However, currently available resources are fragmented, species\u2010limited, and lack AI\u2010powered interfaces for integrated querying. FatPlants 2.0 addresses these issues by integrating ARALIP, PlantFADB, and new Cuphea\/Pennycress experimental data into a unified platform with 14\u2009000 genes\/proteins, 110 pathways across 5 species, and 57\u2009000+ curated publications. The platform features LipidBot, an AI agent enabling natural language queries via graph\u2010based pathway search and retrieval\u2010augmented generation\u2010powered literature retrieval. Users query complex relationships conversationally and receive answers with traceable citations. The graph database models 100+ biological pathways as queryable networks with large language model\u2010guided Cypher generation. By evaluating more than 1000 curated questions, LipidBot achieved 95% accuracy on pathway queries and 92% recall in literature retrieval using optimized embeddings. 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Database and AI agent freely available at\n                    <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"https:\/\/fatplants.net\">https:\/\/fatplants.net<\/jats:ext-link>\n                    with bulk downloads and quarterly updates.\n                  <\/jats:p>","DOI":"10.1111\/tpj.71117","type":"journal-article","created":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T03:54:41Z","timestamp":1789530881000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["<scp>FatPlants<\/scp>\n                    2.0: an\n                    <scp>AI<\/scp>\n                    \u2010powered platform integrating plant lipid genes, pathways, and literature"],"prefix":"10.1111","volume":"127","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-3478-709X","authenticated-orcid":false,"given":"Yongfang","family":"Qin","sequence":"first","affiliation":[{"name":"Department of Electrical Engineering and Computer Science University of Missouri  Columbia Missouri 65201 USA"},{"name":"Christopher S. 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