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In this study, we identified\n                    <jats:italic>MdKNOX15<\/jats:italic>\n                    , a KNOX transcription factor highly expressed in spur\u2010type and dwarfing rootstock varieties, as a critical regulator of plant height. Overexpression of\n                    <jats:italic>MdKNOX15<\/jats:italic>\n                    caused a gibberellin (GA)\u2010deficient dwarf phenotype, whereas VIGS\u2010mediated knockdown increased endogenous GA content and plant height. Exogenous GA alleviated, and uniconazole exacerbated, the dwarfism. Using DAP\u2010seq and RNA\u2010seq, we identified\n                    <jats:italic>MdGA2ox7<\/jats:italic>\n                    and\n                    <jats:italic>MdGA20ox2<\/jats:italic>\n                    as direct target genes. MdKNOX15 activated\n                    <jats:italic>MdGA2ox7<\/jats:italic>\n                    and repressed\n                    <jats:italic>MdGA20ox2<\/jats:italic>\n                    by binding to (T)TGAC elements in their promoters. Functional assays confirmed that\n                    <jats:italic>MdGA2ox7<\/jats:italic>\n                    negatively, and\n                    <jats:italic>MdGA20ox2<\/jats:italic>\n                    positively, regulates apple height. Furthermore, the DELLA homolog MdSLR1b physically interacted with MdKNOX15. Overexpression of\n                    <jats:italic>MdSLR1b<\/jats:italic>\n                    reduced plant height, while its knockdown alleviated the dwarfism induced by\n                    <jats:italic>MdKNOX15<\/jats:italic>\n                    overexpression. MdKNOX15 enhanced MdSLR1b protein stability, especially under GA treatment, and MdSLR1b amplified the transcriptional regulation of downstream genes by MdKNOX15. Collectively, we propose a molecular model in which the\n                    <jats:italic>MdKNOX15<\/jats:italic>\n                    \u2013\n                    <jats:italic>MdSLR1b<\/jats:italic>\n                    \u2013\n                    <jats:italic>MdGA2ox7<\/jats:italic>\n                    \/\n                    <jats:italic>MdGA20ox2<\/jats:italic>\n                    module governs apple plant height, providing a theoretical basis for breeding dwarf apple varieties.\n                  <\/jats:p>","DOI":"10.1111\/tpj.71137","type":"journal-article","created":{"date-parts":[[2026,9,19]],"date-time":"2026-09-19T15:28:31Z","timestamp":1789831711000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["The\n                    <i>MdSLR1b<\/i>\n                    \u2010\n                    <i>MdKNOX15<\/i>\n                    \u2010\n                    <i>MdGA20ox2<\/i>\n                    \/\n                    <i>MdGA2ox7<\/i>\n                    module regulates dwarfing by mediating the gibberellin pathway in apple"],"prefix":"10.1111","volume":"127","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-4338-3547","authenticated-orcid":false,"given":"Rui","family":"Yan","sequence":"first","affiliation":[{"name":"College of Forestry Hebei Agricultural University  Baoding Hebei China"},{"name":"Hebei Provincial Key Laboratory of Forest Tree Germplasm Resources and Forest Protection  Baoding 071000 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinfeng","family":"Zeng","sequence":"additional","affiliation":[{"name":"College of Forestry Hebei Agricultural University  Baoding Hebei China"},{"name":"Hebei Provincial Key Laboratory of Forest Tree Germplasm Resources and Forest Protection  Baoding 071000 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuan","family":"Wang","sequence":"additional","affiliation":[{"name":"State Key Laboratory of North China Crop Improvement and Regulation Hebei Agricultural University  Baoding 071000 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ning","family":"Wang","sequence":"additional","affiliation":[{"name":"College of Forestry Hebei Agricultural University  Baoding Hebei China"},{"name":"Hebei Provincial Key Laboratory of Forest Tree Germplasm Resources and Forest Protection  Baoding 071000 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yilin","family":"Yang","sequence":"additional","affiliation":[{"name":"College of Forestry Hebei Agricultural University  Baoding Hebei China"},{"name":"Hebei Provincial Key Laboratory of Forest Tree Germplasm Resources and Forest Protection  Baoding 071000 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bingyi","family":"Liang","sequence":"additional","affiliation":[{"name":"College of Forestry Hebei Agricultural University  Baoding Hebei China"},{"name":"Hebei Provincial Key Laboratory of Forest Tree Germplasm Resources and Forest Protection  Baoding 071000 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4287-5932","authenticated-orcid":false,"given":"Xuemei","family":"Zhang","sequence":"additional","affiliation":[{"name":"College of Forestry Hebei Agricultural University  Baoding Hebei China"},{"name":"Hebei Provincial Key Laboratory of Forest Tree Germplasm Resources and Forest Protection  Baoding 071000 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guohui","family":"Qi","sequence":"additional","affiliation":[{"name":"College of Forestry Hebei Agricultural University  Baoding Hebei China"},{"name":"Hebei Provincial Key Laboratory of Forest Tree Germplasm Resources and Forest Protection  Baoding 071000 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-7670-6249","authenticated-orcid":false,"given":"Peng","family":"Jia","sequence":"additional","affiliation":[{"name":"College of Forestry Hebei Agricultural University  Baoding Hebei China"},{"name":"Hebei Provincial Key Laboratory of Forest Tree Germplasm Resources and Forest Protection  Baoding 071000 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