{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T21:59:33Z","timestamp":1792101573541,"version":"4.4.0"},"reference-count":89,"publisher":"Wiley","issue":"S1","license":[{"start":{"date-parts":[[2013,1,10]],"date-time":"2013-01-10T00:00:00Z","timestamp":1357776000000},"content-version":"vor","delay-in-days":9,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Transfusion"],"published-print":{"date-parts":[[2013,1]]},"abstract":"\n Background<\/jats:title>\n \n The increasing use of fresh blood group\n O<\/jats:styled-content>\n whole blood in acute trauma medicine makes it important to reevaluate the issue of hemolytic reactions related to the transfusion of\n ABO<\/jats:styled-content>\n \u2010incompatible plasma.\n <\/jats:p>\n <\/jats:sec>\n \n STUDY DESIGN AND METHODS<\/jats:title>\n \n This review summarizes and evaluates published articles and case reports concerning hemolytic reactions in connection with the transfusion of group\n O<\/jats:styled-content>\n whole blood or blood products to nongroup\n O<\/jats:styled-content>\n recipients.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n In 1945\u20101986, 15 nonmilitary publications reported hemolytic transfusion reactions with group\n O<\/jats:styled-content>\n blood\/blood products. All patients recovered except for two fatalities. Late in\n W<\/jats:styled-content>\n orld\n W<\/jats:styled-content>\n ar II and during the\n K<\/jats:styled-content>\n orean and\n V<\/jats:styled-content>\n ietnam wars and onward in\n I<\/jats:styled-content>\n raq and\n A<\/jats:styled-content>\n fghanistan only \u201clow anti\u2010\n A<\/jats:styled-content>\n , anti\u2010\n B<\/jats:styled-content>\n titer\u201d group\n O<\/jats:styled-content>\n whole blood has been used as universal blood. In spite of a large number of units transfused, there are no reports of hemolytic reactions. Twenty\u2010five publications report hemolytic reactions after transfusion of group\n O<\/jats:styled-content>\n platelets to nongroup\n O<\/jats:styled-content>\n recipients. In all patients but one, the titer of the implicated\n A<\/jats:styled-content>\n \u2010 or\n B<\/jats:styled-content>\n \u2010antibody was >100 (saline) or >400 (antiglobulin) and all cases with an infused volume of incompatible plasma <200\u2009\n mL<\/jats:styled-content>\n were related to anti\u2010\n A<\/jats:styled-content>\n or anti\u2010\n B<\/jats:styled-content>\n antiglobulin titers >1000.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n \n In emergency lifesaving resuscitation, the risk of hemolytic transfusion reactions from transfusion of group\n O<\/jats:styled-content>\n blood to nongroup\n O<\/jats:styled-content>\n recipients constitutes risk that is outweighed by the benefits. A low titer of anti\u2010\n A<\/jats:styled-content>\n \/\n B<\/jats:styled-content>\n will minimize the risk for a hemolytic reaction, particularly if the screening is repeated after an immunization episode, e.g., blood transfusion, vaccination, or pregnancy.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/trf.12045","type":"journal-article","created":{"date-parts":[[2013,1,10]],"date-time":"2013-01-10T12:46:12Z","timestamp":1357821972000},"source":"Crossref","is-referenced-by-count":130,"title":["Risks of hemolysis due to anti\u2010\n A<\/scp>\n and anti\u2010\n B<\/scp>\n caused by the transfusion of blood or blood components containing\n ABO<\/scp>\n \u2010incompatible plasma"],"prefix":"10.1111","volume":"53","author":[{"given":"Olle","family":"Bers\u00e9us","sequence":"first","affiliation":[{"name":"Department of Transfusion Medicine \u00d6rebro University Hospital \u00d6rebro Sweden"},{"name":"Swedish Army Special Forces Sweden"},{"name":"US Army Medical Corps 212th Combat Support Hospital Miseau Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kjell","family":"Boman","sequence":"additional","affiliation":[{"name":"Department of Transfusion Medicine \u00d6rebro University Hospital \u00d6rebro Sweden"},{"name":"Swedish Army Special Forces Sweden"},{"name":"US Army Medical Corps 212th Combat Support Hospital Miseau Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shawn C.","family":"Nessen","sequence":"additional","affiliation":[{"name":"Department of Transfusion Medicine \u00d6rebro University Hospital \u00d6rebro Sweden"},{"name":"Swedish Army Special Forces Sweden"},{"name":"US Army Medical Corps 212th Combat Support Hospital Miseau Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lars A.","family":"Westerberg","sequence":"additional","affiliation":[{"name":"Department of Transfusion Medicine \u00d6rebro University Hospital \u00d6rebro Sweden"},{"name":"Swedish Army Special Forces Sweden"},{"name":"US Army Medical Corps 212th Combat Support Hospital Miseau Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,1,10]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.ta.0000219013.64168.b2"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0b013e31817e2ef9"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/TA.0b013e31819d85fb"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biologicals.2009.10.007"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/9780470986868"},{"key":"e_1_2_5_7_1","first-page":"451","article-title":"Destruction of IgG anti\u2010A sensitized erythrocytes by mononuclear leucocytes from normal and ABO hemolytic disease affected children","volume":"55","author":"Romano EL","year":"1984","journal-title":"Clin Exp Immunol"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.110.2.221"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(52)91548-1"},{"key":"e_1_2_5_10_1","first-page":"478","article-title":"Accidents de la transfusion chez de receveurs de grope A ayant recu du sang de groupe O; 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