{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T15:38:23Z","timestamp":1762875503149},"reference-count":40,"publisher":"Wiley","issue":"10pt2","license":[{"start":{"date-parts":[[2013,10,17]],"date-time":"2013-10-17T00:00:00Z","timestamp":1381968000000},"content-version":"vor","delay-in-days":16,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Transfusion"],"published-print":{"date-parts":[[2013,10]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Information regarding the risk factors for human immunodeficiency virus (<jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content>) infection among <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>hinese donors is important for understanding the trend of <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content> transmission routes and for developing effective donor behavioral screening policies.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design and Methods<\/jats:title><jats:p>In 2009 to 2011, a total of 77 <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content>\u2010positive and 649 <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content>\u2010negative consented donors who screened nonreactive for hepatitis\u2009<jats:styled-content style=\"fixed-case\">B<\/jats:styled-content> virus, hepatitis\u2009<jats:styled-content style=\"fixed-case\">C<\/jats:styled-content> virus, syphilis, and alanine aminotransferase in four <jats:styled-content style=\"fixed-case\">R<\/jats:styled-content>etrovirus <jats:styled-content style=\"fixed-case\">E<\/jats:styled-content>pidemiology <jats:styled-content style=\"fixed-case\">D<\/jats:styled-content>onor <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>tudy\u2010<jats:styled-content style=\"fixed-case\">II C<\/jats:styled-content>hinese regions received and completed a questionnaire by mail regarding their recent and past medical procedures, drug use, and sexual behaviors, etc. Exploratory and confirmatory factor analyses grouped questions into three risk factors. Multivariable logistic regression analysis examined the relationship between risk factors and <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content> status adjusting for center, age, sex, and education.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The three risk factors were test\u2010seeking tendency, medical\u2010related risks, and behavioral risks. In multivariable logistic regression analysis, greater test\u2010seeking tendency and behavioral risks were associated with <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content> infection, with the adjusted odds ratios (<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>s) being 2.2 (95% confidence interval [<jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>], 1.2\u20104.1) and 3.8 (95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>, 1.8\u20107.9), respectively, but medical risks were not (<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>, 1.2; 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>, 0.6\u20102.2). In comparison to less high school education, high school and more education was associated with lower risks for <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content> infection, with the <jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>s being 0.35 (95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>, 0.17\u20100.70) and 0.17 (95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>, 0.09\u20100.33), respectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Test\u2010seeking tendency and high\u2010risk sexual behaviors are important predictors of <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content> infection in <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>hinese blood donors, suggesting that the health history inquiry used in donor selection process needs improvement to defer high\u2010risk donors more effectively.<\/jats:p><\/jats:sec>","DOI":"10.1111\/trf.12062","type":"journal-article","created":{"date-parts":[[2013,1,11]],"date-time":"2013-01-11T02:37:13Z","timestamp":1357871833000},"page":"2431-2440","source":"Crossref","is-referenced-by-count":13,"title":["An analysis of risk factors for human immunodeficiency virus infection among <scp>C<\/scp>hinese blood donors"],"prefix":"10.1111","volume":"53","author":[{"given":"Jingxing","family":"Wang","sequence":"first","affiliation":[{"name":"Institute of Blood Transfusion Chinese Academy of Medical Sciences  Chengdu P.R. 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