{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T04:48:44Z","timestamp":1791175724016,"version":"4.1.0"},"reference-count":16,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2013,7,5]],"date-time":"2013-07-05T00:00:00Z","timestamp":1372982400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Transfusion"],"published-print":{"date-parts":[[2014,1]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>The management of pregnant women with anti\u2010Jsb is challenging due to the paucity of antigen\u2010negative blood for fetal and neonatal transfusion.<\/jats:p><\/jats:sec><jats:sec><jats:title>Case Report<\/jats:title><jats:p>A 29\u2010year\u2010old woman with anti\u2010<jats:styled-content style=\"fixed-case\">Jsb<\/jats:styled-content> was referred for assessment of recurrent fetal losses. With the presence of the sister as a historically matched donor, she was planned for active surveillance for fetal anemia during pregnancy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design and Methods<\/jats:title><jats:p>The fetus remained well until 21 weeks of gestation when signs of fetal anemia and early hydrops fetalis were noted. Anti\u2010<jats:styled-content style=\"fixed-case\">Jsb<\/jats:styled-content> titer was at 128. The sister's red blood cells (<jats:styled-content style=\"fixed-case\">RBCs<\/jats:styled-content>) were cross\u2010match incompatible. Urgent intrauterine transfusion (<jats:styled-content style=\"fixed-case\">IUT<\/jats:styled-content>) was performed with washed irradiated maternal <jats:styled-content style=\"fixed-case\">RBCs<\/jats:styled-content>, donated after cessation of heparin. The mother was given intravenous iron (<jats:styled-content style=\"fixed-case\">IV<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">Fe<\/jats:styled-content>) and continued on weekly recombinant human erythropoietin (<jats:styled-content style=\"fixed-case\">rHu<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">EPO<\/jats:styled-content>).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Repeated IUTs were needed every 1 to 3 weeks. Throughout a 7\u2010week period, three maternal donations were performed with total donated whole blood volume of 1250\u2009<jats:styled-content style=\"fixed-case\">mL<\/jats:styled-content>, supporting four IUTs. At 29 weeks of gestation, the procedure was complicated by umbilical cord hematoma necessitating urgent cesarean section. A male newborn was delivered, transfused at birth, and subsequently treated with phototherapy and five top\u2010up transfusions.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This case represents a successful example of managing hemolytic disease of the fetus due to a rare antibody using maternal blood. It also supports previous data on safety of maternal donations during pregnancy and the use of combination of <jats:styled-content style=\"fixed-case\">rHu<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">EPO<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">IV<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">Fe<\/jats:styled-content> as a supportive measure.<\/jats:p><\/jats:sec>","DOI":"10.1111\/trf.12331","type":"journal-article","created":{"date-parts":[[2013,7,5]],"date-time":"2013-07-05T12:10:23Z","timestamp":1373026223000},"page":"238-243","source":"Crossref","is-referenced-by-count":18,"title":["Successful management of severe hemolytic disease of the fetus due to anti\u2010<scp>Jsb<\/scp> using intrauterine transfusions with serial maternal blood donations: a case report and a review of the literature"],"prefix":"10.1111","volume":"54","author":[{"given":"Arwa Z.","family":"Al Riyami","sequence":"first","affiliation":[{"name":"Department of Hematology Sultan Qaboos University Hospital  Muscat Oman"},{"name":"Department of Obstetrics and Gynecology Sultan Qaboos University Hospital  Muscat Oman"},{"name":"Department of Obstetrics and Gynecology Royal Hospital  Muscat Oman"},{"name":"Department of Hematology Royal Hospital  Muscat Oman"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Moza","family":"Al Salmani","sequence":"additional","affiliation":[{"name":"Department of Hematology Sultan Qaboos University Hospital  Muscat Oman"},{"name":"Department of Obstetrics and Gynecology Sultan Qaboos University Hospital  Muscat Oman"},{"name":"Department of Obstetrics and Gynecology Royal Hospital  Muscat Oman"},{"name":"Department of Hematology Royal Hospital  Muscat Oman"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sabria","family":"Al Hashami","sequence":"additional","affiliation":[{"name":"Department of Hematology Sultan Qaboos 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Sultan Qaboos University Hospital  Muscat Oman"},{"name":"Department of Obstetrics and Gynecology Royal Hospital  Muscat Oman"},{"name":"Department of Hematology Royal Hospital  Muscat Oman"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Halima","family":"Al Balushi","sequence":"additional","affiliation":[{"name":"Department of Hematology Sultan Qaboos University Hospital  Muscat Oman"},{"name":"Department of Obstetrics and Gynecology Sultan Qaboos University Hospital  Muscat Oman"},{"name":"Department of Obstetrics and Gynecology Royal Hospital  Muscat Oman"},{"name":"Department of Hematology Royal Hospital  Muscat Oman"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nihal","family":"Al Riyami","sequence":"additional","affiliation":[{"name":"Department of Hematology Sultan Qaboos University Hospital  Muscat Oman"},{"name":"Department of Obstetrics and Gynecology Sultan Qaboos University Hospital  Muscat Oman"},{"name":"Department of Obstetrics and 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Muscat Oman"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saif","family":"Al Hosni","sequence":"additional","affiliation":[{"name":"Department of Hematology Sultan Qaboos University Hospital  Muscat Oman"},{"name":"Department of Obstetrics and Gynecology Sultan Qaboos University Hospital  Muscat Oman"},{"name":"Department of Obstetrics and Gynecology Royal Hospital  Muscat Oman"},{"name":"Department of Hematology Royal Hospital  Muscat Oman"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Murtadha","family":"Al\u2010Khabori","sequence":"additional","affiliation":[{"name":"Department of Hematology Sultan Qaboos University Hospital  Muscat Oman"},{"name":"Department of Obstetrics and Gynecology Sultan Qaboos University Hospital  Muscat Oman"},{"name":"Department of Obstetrics and Gynecology Royal Hospital  Muscat Oman"},{"name":"Department of Hematology Royal Hospital  Muscat 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