{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T03:30:42Z","timestamp":1787628642290,"version":"build-2736575974"},"reference-count":14,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2014,1,8]],"date-time":"2014-01-08T00:00:00Z","timestamp":1389139200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Transfusion"],"published-print":{"date-parts":[[2014,7]]},"abstract":"Background<\/jats:title>Group AB<\/jats:styled-content> plasma, which lacks anti\u2010A<\/jats:styled-content> and anti\u2010B<\/jats:styled-content> isohemagglutinins, is issued for emergency transfusion when a patient's ABO<\/jats:styled-content> group is unknown, but the relative scarcity of group AB<\/jats:styled-content> blood donors limits its availability. We sought to establish a thawed plasma inventory to improve the rapid availability of plasma in the emergency release setting but were concerned about potential wastage of group AB<\/jats:styled-content> plasma.<\/jats:p><\/jats:sec>Study Design and Methods<\/jats:title>Recognizing that plasma\u2010incompatible apheresis platelets are routinely transfused and only rarely result in hemolytic reactions if the donor is blood group O<\/jats:styled-content>, and considering that group A<\/jats:styled-content> plasma would be compatible with approximately 85% of our patient population, we instituted an emergency release policy whereby thawed group A<\/jats:styled-content> plasma is issued to all patients of unknown blood group or if compatible plasma is not available. ABO<\/jats:styled-content>\u2010compatible plasma is then issued, if needed, once the patient's blood group is determined. We prospectively assessed the outcomes of all patients who received incompatible plasma under our policy.<\/jats:p><\/jats:sec>Results<\/jats:title>During the first 5 years under this policy, 385 emergency release requests for plasma were received by our blood bank. Among them, 23 group B<\/jats:styled-content> or AB<\/jats:styled-content> patients met criteria for receiving a median of 2 units of incompatible group A<\/jats:styled-content> plasma. No hemolytic transfusion reactions or other adverse events related to transfusion were seen in any of these 23 patients.<\/jats:p><\/jats:sec>Conclusion<\/jats:title>We propose that group A<\/jats:styled-content> plasma may be an acceptable alternative to AB<\/jats:styled-content> plasma as the first option in the emergency release setting.<\/jats:p><\/jats:sec>","DOI":"10.1111\/trf.12537","type":"journal-article","created":{"date-parts":[[2014,1,9]],"date-time":"2014-01-09T02:20:44Z","timestamp":1389234044000},"page":"1751-1755","source":"Crossref","is-referenced-by-count":45,"title":["Is group A<\/scp> thawed plasma suitable as the first option for emergency release transfusion? 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