{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T02:57:19Z","timestamp":1785380239362,"version":"3.55.0"},"reference-count":30,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2014,9,11]],"date-time":"2014-09-11T00:00:00Z","timestamp":1410393600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Transfusion"],"published-print":{"date-parts":[[2015,3]]},"abstract":"Background<\/jats:title>T<\/jats:styled-content>rypanosoma cruzi<\/jats:italic> is the causal agent of C<\/jats:styled-content>hagas disease. Of the M<\/jats:styled-content>exican states, V<\/jats:styled-content>eracruz is among the most affected by this sickness. However, the actual epidemiologic situation of this disease is not well understood. This study sought to determine the prevalence and risk factors for C<\/jats:styled-content>hagas disease among V<\/jats:styled-content>eracruzan blood donors.<\/jats:p><\/jats:sec>Study Design and Methods<\/jats:title>Blood donors from C<\/jats:styled-content>entro E<\/jats:styled-content>statal de la T<\/jats:styled-content>ransfusion S<\/jats:styled-content>anguinea de V<\/jats:styled-content>eracruz were included. Blood units were serologically scrutinized for T<\/jats:styled-content>.\u2009cruzi<\/jats:italic> antibodies using enzyme\u2010linked immunosorbent assays. To identify risk factors, demographic data were collected from the medical records of positive donors and a representative sample of healthy donors.<\/jats:p><\/jats:sec>Results<\/jats:title>A total of 87,232 donations were analyzed, and the mean prevalence of T<\/jats:styled-content>.\u2009cruzi<\/jats:italic> was found to be 0.5%. The identified risk factors were living as a couple and in a rural area, having a low level of education, being a farmer, dwelling in a house with earthen or wooden walls and a tile or thatch roof, living with domestic animals, recognition of or exposure to triatomine bugs, and residing in the H<\/jats:styled-content>uasteca region. An increase of rural\u2010living donors infected with T<\/jats:styled-content>.\u2009cruzi<\/jats:italic> was observed in the past 3 years of the study period.<\/jats:p><\/jats:sec>Conclusion<\/jats:title>The prevalence to C<\/jats:styled-content>hagas disease has not decreased in the past decade and the disease appears to be spreading in rural areas of V<\/jats:styled-content>eracruz. This increases the risk of T<\/jats:styled-content>.\u2009cruzi<\/jats:italic> transfusion\u2010transmitted infection, not only in V<\/jats:styled-content>eracruz and M<\/jats:styled-content>exico, but also in other nonendemic countries that receive immigrants from V<\/jats:styled-content>eracruz S<\/jats:styled-content>tate.<\/jats:p><\/jats:sec>","DOI":"10.1111\/trf.12860","type":"journal-article","created":{"date-parts":[[2014,9,11]],"date-time":"2014-09-11T08:54:20Z","timestamp":1410425660000},"page":"647-656","source":"Crossref","is-referenced-by-count":13,"title":["Prevalence of T<\/scp>rypanosoma cruzi<\/i> antibodies in blood donors from V<\/scp>eracruz S<\/scp>tate, M<\/scp>exico"],"prefix":"10.1111","volume":"55","author":[{"given":"Pablo","family":"Hern\u00e1ndez\u2010Romano","sequence":"first","affiliation":[{"name":"Laboratorio de Biolog\u00eda Molecular Centro Estatal de la Transfusi\u00f3n Sangu\u00ednea del Estado de Veracruz Veracruz Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mireya","family":"C\u00e1mara\u2010Contreras","sequence":"additional","affiliation":[{"name":"Laboratorio de Gen\u00e9tica y Biolog\u00eda Molecular Hospital Regional de Alta Especialidad de Veracruz Veracruz Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elid\u00e9","family":"Bravo\u2010Sarmiento","sequence":"additional","affiliation":[{"name":"Laboratorio de Biolog\u00eda Molecular Centro Estatal de la Transfusi\u00f3n Sangu\u00ednea del Estado de Veracruz Veracruz Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0996-6966","authenticated-orcid":false,"given":"Nayali","family":"L\u00f3pez\u2010Balderas","sequence":"additional","affiliation":[{"name":"Laboratorio de Gen\u00e9tica y Biolog\u00eda Molecular Hospital Regional de Alta Especialidad de Veracruz Veracruz Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,9,11]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1136\/pgmj.2006.047357"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1537-2995.2009.02107.x"},{"key":"e_1_2_8_4_1","unstructured":"World Healt Organization.Neglected tropical disease.2014. 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