{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,10]],"date-time":"2026-01-10T03:16:16Z","timestamp":1768014976105,"version":"3.49.0"},"reference-count":28,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2014,11,18]],"date-time":"2014-11-18T00:00:00Z","timestamp":1416268800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Transfusion"],"published-print":{"date-parts":[[2014,12]]},"abstract":"<jats:p>As <jats:styled-content style=\"fixed-case\">E<\/jats:styled-content>bola virus has infected thousands of individuals in <jats:styled-content style=\"fixed-case\">W<\/jats:styled-content>est <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>frica, there is growing concern about the appropriate response of hospitals in developed nations caring for patients and handling laboratory specimens for patients suspected of <jats:styled-content style=\"fixed-case\">E<\/jats:styled-content>bola virus disease (<jats:styled-content style=\"fixed-case\">EVD<\/jats:styled-content>). Guidelines for caring for <jats:styled-content style=\"fixed-case\">EVD<\/jats:styled-content> patients are proliferating rapidly from national and state public health authorities, professional societies, and individual hospitals. It is no surprise that they differ from one another, and some very conservative recommendations call for suspension of routine laboratory testing, including pretransfusion testing. <jats:styled-content style=\"fixed-case\">EVD<\/jats:styled-content> is transmitted by direct contact with blood, secretions, organs, and other body fluids and not by airborne routes. Based on experimental and observational data, the <jats:styled-content style=\"fixed-case\">US C<\/jats:styled-content>enters for <jats:styled-content style=\"fixed-case\">D<\/jats:styled-content>isease <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>ontrol and <jats:styled-content style=\"fixed-case\">P<\/jats:styled-content>revention (<jats:styled-content style=\"fixed-case\">CDC<\/jats:styled-content>) recommends that clinicians follow contact and droplet precautions. Laboratory personnel are required to follow the blood\u2010borne pathogen standard, especially the use of appropriate barriers consisting of gloves, gown, goggles, mask to cover nose and mouth, and plexiglass shield, where splashes of potentially infectious materials may be generated. Their recommendations are permissive of clinically appropriate laboratory testing, including pretransfusion testing, using barrier isolation precautions. Most individuals with suspected <jats:styled-content style=\"fixed-case\">EVD<\/jats:styled-content> will have a fever of another etiology, such as <jats:italic><jats:styled-content style=\"fixed-case\">P<\/jats:styled-content>lasmodium\u2009falciparum<\/jats:italic> malaria. We believe that forgoing all routine pretransfusion laboratory testing may result in a greater increase in poor clinical outcomes than any diminution in the risks to laboratory personnel will justify. It is imperative for all laboratory directors, working with institutional infection control and safety personnel, to evaluate their hospital policies for potentially infectious patients and provide a safe environment for their patients and employees.<\/jats:p>","DOI":"10.1111\/trf.12913","type":"journal-article","created":{"date-parts":[[2014,11,18]],"date-time":"2014-11-18T08:09:19Z","timestamp":1416298159000},"page":"3247-3251","source":"Crossref","is-referenced-by-count":28,"title":["Ebola virus disease, transmission risk to laboratory personnel, and pretransfusion testing"],"prefix":"10.1111","volume":"54","author":[{"given":"Louis M.","family":"Katz","sequence":"first","affiliation":[{"name":"America's Blood Centers  Washington DC"},{"name":"Internal Medicine, Infectious Diseases Carver College of Medicine University of Iowa  Iowa City IA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aaron A.R.","family":"Tobian","sequence":"additional","affiliation":[{"name":"Department of Pathology Division of Transfusion Medicine Johns Hopkins University  Baltimore MD"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,11,18]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2014.11170"},{"key":"e_1_2_8_3_1","unstructured":"World Health Organization.Barriers to rapid containment of the Ebola outbreak. 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