{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,9,23]],"date-time":"2023-09-23T20:10:55Z","timestamp":1695499855966},"reference-count":37,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2015,2,27]],"date-time":"2015-02-27T00:00:00Z","timestamp":1424995200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"US President's Emergency Plan for AIDS Relief","award":["n\/a"],"award-info":[{"award-number":["n\/a"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Transfusion"],"published-print":{"date-parts":[[2015,7]]},"abstract":"<jats:sec><jats:title>BACKGROUND<\/jats:title><jats:p>Few African countries separate blood donations into components; however, demand for platelets (PLTs) is increasing as regional capacity to treat causes of thrombocytopenia, including chemotherapy, increases. Namibia introduced single\u2010donor apheresis PLT collections in 2007 to increase PLT availability while reducing exposure to multiple donors via pooling. This study describes the impact this transition had on PLT availability and safety in Namibia.<\/jats:p><\/jats:sec><jats:sec><jats:title>STUDY DESIGN AND METHODS<\/jats:title><jats:p>Annual national blood collections and PLT units issued data were extracted from a database maintained by the Blood Transfusion Service of Namibia (NAMBTS). Production costs and unit prices were analyzed.<\/jats:p><\/jats:sec><jats:sec><jats:title>RESULTS<\/jats:title><jats:p>In 2006, NAMBTS issued 771 single and pooled PLT doses from 3054 whole blood (WB) donations (drawn from 18,422 WB donations). In 2007, NAMBTS issued 486 single and pooled PLT doses from 1477 WB donations (drawn from 18,309 WB donations) and 131 single\u2010donor PLT doses. By 2011, NAMBTS issued 837 single\u2010donor PLT doses per year, 99.1% of all PLT units. Of 5761 WB donations from which PLTs were made in 2006 to 2011, a total of 20 (0.35%) were from donors with confirmed test results for human immunodeficiency virus or other transfusion\u2010transmissible infections (TTIs). Of 2315 single\u2010donor apheresis donations between 2007 and 2011, none of the 663 donors had a confirmed positive result for any pathogen. As apheresis replaced WB\u2010derived PLTs, apheresis production costs dropped by a mean of 8.2% per year, while pooled PLT costs increased by an annual mean of 21.5%. Unit prices paid for apheresis\u2010 and WB\u2010derived PLTs increased by 9 and 7.4% per year on average, respectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>CONCLUSION<\/jats:title><jats:p>Namibia's PLT transition shows that collections from repeat apheresis donors can reduce TTI risk and production costs.<\/jats:p><\/jats:sec>","DOI":"10.1111\/trf.13049","type":"journal-article","created":{"date-parts":[[2015,2,27]],"date-time":"2015-02-27T15:11:13Z","timestamp":1425049873000},"page":"1685-1692","source":"Crossref","is-referenced-by-count":5,"title":["Namibia's transition from whole blood\u2013derived pooled platelets to single\u2010donor apheresis platelet collections"],"prefix":"10.1111","volume":"55","author":[{"given":"John P.","family":"Pitman","sequence":"first","affiliation":[{"name":"Division of Global HIV\/AIDS Center for Global Health US Centers for Disease Control and Prevention Atlanta Georgia"},{"name":"University Medical Center Groningen (UMCG) Institute of Science in Healthy Aging &amp; health caRE (SHARE) Groningen NL"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sridhar V.","family":"Basavaraju","sequence":"additional","affiliation":[{"name":"Division of Global HIV\/AIDS Center for Global Health US Centers for Disease Control and Prevention Atlanta Georgia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ray W.","family":"Shiraishi","sequence":"additional","affiliation":[{"name":"Division of Global HIV\/AIDS Center for Global Health US Centers for Disease Control and Prevention Atlanta Georgia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert","family":"Wilkinson","sequence":"additional","affiliation":[{"name":"Blood Transfusion Service of Namibia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bjorn","family":"von Finckenstein","sequence":"additional","affiliation":[{"name":"Blood Transfusion Service of Namibia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David W.","family":"Lowrance","sequence":"additional","affiliation":[{"name":"Division of Global HIV\/AIDS Center for Global Health, US Centers for Disease Control and Prevention Windhoek Namibia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anthony A.","family":"Marfin","sequence":"additional","affiliation":[{"name":"Division of Global HIV\/AIDS Center for Global Health US Centers for Disease Control and Prevention Atlanta Georgia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maarten","family":"Postma","sequence":"additional","affiliation":[{"name":"Department of Pharmacy Unit of PharmacoEpidemiology &amp; PharmacoEconomics (PE2) University of Groningen Groningen the Netherlands"},{"name":"University Medical Center Groningen (UMCG) Institute of Science in Healthy Aging &amp; health caRE (SHARE) Groningen NL"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mary","family":"Mataranyika","sequence":"additional","affiliation":[{"name":"Namibia Ministry of Health and Social Services Directorate for Clinical Support Services"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cees Th.","family":"Smit Sibinga","sequence":"additional","affiliation":[{"name":"ID Consulting for International Development of Transfusion Medicine"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,2,27]]},"reference":[{"key":"e_1_2_8_2_1","volume-title":"Status of blood safety in the WHO African region: report of the 2004 survey","author":"World Health Organization","year":"2007"},{"key":"e_1_2_8_3_1","first-page":"23","article-title":"Quality assurance set\u2010up in a blood transfusion facility: the experience of the National Blood Transfusion Center of Mali]","volume":"25","author":"Kouriba B","year":"2010","journal-title":"Mali Med"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3148.2010.01015.x"},{"key":"e_1_2_8_5_1","first-page":"429","article-title":"One year clinical audit of the use of blood and blood components at a tertiary hospital in Nigeria","volume":"12","author":"Arewa OP","year":"2009","journal-title":"Niger J Clin Pract"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1537-2995.2008.01697.x"},{"key":"e_1_2_8_7_1","unstructured":"DiakiteM DiawaraSI TchogangNT et al . [Knowledge and attitudes of medical personnel in blood transfusion in Bamako Mali].Transfus Clin Biol2012;19:74\u20107. French."},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tmrv.2011.07.006"},{"key":"e_1_2_8_9_1","doi-asserted-by":"crossref","unstructured":"QureshiH LoweD DobsonP et al.National comparative audit of the use of platelet transfusions in the UK.Transfus Clin Biol2007;14:509\u201013.","DOI":"10.1016\/j.tracli.2008.01.002"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/9781444303513"},{"key":"e_1_2_8_11_1","first-page":"132","article-title":"Recommendations for the transfusion of plasma and platelets","volume":"7","author":"Liumbruno G","year":"2009","journal-title":"Blood Transfus"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2012-02-387092"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/00002030-199307000-00014"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0035-9203(03)90070-8"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3148.2010.00992.x"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1423-0410.2012.01628.x"},{"key":"e_1_2_8_17_1","volume-title":"(WHO) aide\u2010memoire for national health authorities: safe blood components","year":"2005"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1086\/499363"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1423-0410.2010.01376.x"},{"key":"e_1_2_8_20_1","volume-title":"Standards for the practice of blood transfusion in Namibia","author":"Government of the Republic of Namibia","year":"2010"},{"key":"e_1_2_8_21_1","first-page":"28","article-title":"Twinning in paediatric oncology\u2014an African experience","volume":"102","author":"Stefan DC","year":"2012","journal-title":"S Afr Med J"},{"key":"e_1_2_8_22_1","first-page":"885","article-title":"Incidence and frequency rates of childhood cancer in Namibia","volume":"87","author":"Wessels G","year":"1997","journal-title":"S Afr Med J"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.3109\/08880019609033368"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1751-2824.2010.01366.x"},{"key":"e_1_2_8_25_1","unstructured":"Government of the Republic of Namibia. Global AIDS response progress reporting 2012: monitoring the 2011 political declaration on HIV\/AIDS. 2012 [cited 2014 Oct 24]. Available from:http:\/\/www.unaids.org\/en\/dataanalysis\/knowyourresponse\/countryprogressreports\/2012countries\/ce_NA_Narrative_Report[1].pdf"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-374432-6.00006-3"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1537-2995.2002.00200.x"},{"key":"e_1_2_8_28_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1537-2995.2009.02110.x"},{"key":"e_1_2_8_29_1","volume-title":"International statistical classification of diseases and related health problems 10th revision","author":"World Health Organization","year":"1994"},{"key":"e_1_2_8_30_1","first-page":"1","article-title":"The impact of external donor support through the U.S. President's Emergency Plan for AIDS Relief on the cost of red cell concentrate in Namibia, 2004\u20102011","volume":"23","author":"Pitman JP","year":"2014","journal-title":"Blood Transfus"},{"key":"e_1_2_8_31_1","volume-title":"Population projections","author":"Government of the Republic of Namibia","year":"2006"},{"key":"e_1_2_8_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tracli.2009.09.004"},{"key":"e_1_2_8_33_1","doi-asserted-by":"publisher","DOI":"10.1111\/trf.12299"},{"key":"e_1_2_8_34_1","doi-asserted-by":"crossref","unstructured":"NamululiBA GuerrieriC DramaixM. [Impact of method of recruitment of blood donors on the prevalence of HIV and HBV in Bukavu DR Congo].Med Sante Trop2012;22:69\u201074. French.","DOI":"10.1684\/mst.2012.0028"},{"key":"e_1_2_8_35_1","volume-title":"India contributes to the fight against cancer in Namibia","author":"International Atomic Energy Agency","year":"2011"},{"key":"e_1_2_8_36_1","first-page":"1577","article-title":"Progress toward strengthening national blood transfusion services\u201414 countries, 2008\u20102010","volume":"60","author":"Centers for Disease Control and Prevention (CDC)","year":"2011","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"e_1_2_8_37_1","unstructured":"Centers for Disease Control and Prevention (CDC).Progress toward strengthening blood transfusion services\u201414 countries 2003\u20102007.MMWR Morb Mortal Wkly Rep2008;57:1273\u20107."},{"key":"e_1_2_8_38_1","unstructured":"PEPFAR Stewardship and Oversight Act of 2013. In: U.S. Senate editor. Amendment to the United States Leadership 8 Against HIV\/AIDS Tuberculosis and Malaria Act of 9 2003 (22 U.S.C. 7611(f)(1)). Washington (DC): United States Senate; 2013."}],"container-title":["Transfusion"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Ftrf.13049","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/trf.13049","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,23]],"date-time":"2023-09-23T19:43:34Z","timestamp":1695498214000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/trf.13049"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,2,27]]},"references-count":37,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2015,7]]}},"alternative-id":["10.1111\/trf.13049"],"URL":"https:\/\/doi.org\/10.1111\/trf.13049","archive":["Portico"],"relation":{},"ISSN":["0041-1132","1537-2995"],"issn-type":[{"value":"0041-1132","type":"print"},{"value":"1537-2995","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,2,27]]}}}