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Recent evidence demonstrates that patients with cirrhosis exist in a state of hemostatic rebalance. Accordingly, routine tests inadequately represent hemostatic alterations in these patients. Unfortunately, these tests are regularly used to guide the transfusion of blood components with the assumption that they will correct laboratory abnormalities and improve hemostasis in a bleeding patient or prevent excessive bleeding following a procedure. With an absence of both accurate laboratory testing to assess hemostasis and evidence\u2010based guidelines to direct the transfusion of blood components, management of patients with cirrhosis poses a significant challenge to clinicians. Therefore, we developed multidisciplinary guidelines for the periprocedural transfusion of blood components in patients with cirrhosis based on concurrent evidence and personal experience at our medical center.<\/jats:p>","DOI":"10.1111\/trf.13495","type":"journal-article","created":{"date-parts":[[2016,2,15]],"date-time":"2016-02-15T03:03:34Z","timestamp":1455505414000},"page":"791-798","source":"Crossref","is-referenced-by-count":14,"title":["How do we transfuse blood components in cirrhotic patients undergoing gastrointestinal procedures?"],"prefix":"10.1111","volume":"56","author":[{"given":"Sean G.","family":"Yates","sequence":"first","affiliation":[{"name":"Department of Pathology, Division of Transfusion Medicine and Hemostasis University of Texas Southwestern Medical Center Dallas Texas"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chakri","family":"Gavva","sequence":"additional","affiliation":[{"name":"Department of Pathology, Division of Transfusion 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