{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,4]],"date-time":"2025-12-04T14:34:42Z","timestamp":1764858882590},"reference-count":27,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2016,7,7]],"date-time":"2016-07-07T00:00:00Z","timestamp":1467849600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Medical University of \u0141\u00f3d\u017a","award":["503\/1-093-02\/503-16-001"],"award-info":[{"award-number":["503\/1-093-02\/503-16-001"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Transfusion"],"published-print":{"date-parts":[[2016,10]]},"abstract":"<jats:sec><jats:title>BACKGROUND<\/jats:title><jats:p>The treatment of patients with acute leukemia, who due to their religious beliefs refuse to accept blood transfusion, is a great challenge for hematologists.<\/jats:p><\/jats:sec><jats:sec><jats:title>CASE REPORT<\/jats:title><jats:p>We present a case of acute pre\u2010T\u2010lymphoblastic leukemia in a Jehovah's Witness who did not accept blood transfusion during chemotherapy. Standard induction and consolidation chemotherapy was used (according to the PALG ALL\u20106 regiment).<\/jats:p><\/jats:sec><jats:sec><jats:title>RESULTS<\/jats:title><jats:p>During consolidation cycles, darbepoietin alfa, intravenous iron, and total parenteral nutrition was administered. Extreme (Hb\u00a0&lt;\u00a05 g\/dL), long\u2010lasting (41 days) anemia was observed with the lowest Hb concentration amounting to 1.3 g\/dL (lasting 7 days).<\/jats:p><\/jats:sec><jats:sec><jats:title>CONCLUSION<\/jats:title><jats:p>We believe this to be the lowest Hb value observed, particularly one that persisted for such a long period of time and resulted in the patient surviving without consequences. The patient remains in complete remission for more than 2\u00a0years after diagnosis.<\/jats:p><\/jats:sec>","DOI":"10.1111\/trf.13703","type":"journal-article","created":{"date-parts":[[2016,7,7]],"date-time":"2016-07-07T07:22:41Z","timestamp":1467876161000},"page":"2438-2442","source":"Crossref","is-referenced-by-count":6,"title":["Long\u2010lasting extreme anemia during the therapy of acute lymphoblastic leukemia in a Jehovah's Witness patient"],"prefix":"10.1111","volume":"56","author":[{"given":"Krzysztof","family":"Chojnowski","sequence":"first","affiliation":[{"name":"Department of Hemostasis Medical University of \u0141\u00f3d\u017a, and the \u0141\u00f3d\u017a Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Agnieszka","family":"Janus","sequence":"additional","affiliation":[{"name":"Department of Hematology Copernicus Memorial Hospital \u0141\u00f3d\u017a 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