{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,2,23]],"date-time":"2024-02-23T10:22:32Z","timestamp":1708683752310},"reference-count":7,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2016,11,10]],"date-time":"2016-11-10T00:00:00Z","timestamp":1478736000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Transfusion"],"published-print":{"date-parts":[[2017,2]]},"abstract":"<jats:sec><jats:title>BACKGROUND<\/jats:title><jats:p>Separators use 1960s sex\u2010based nomograms to estimate apheresis donor blood volume and to calculate the 15% maximum extracorporeal and collection volumes. As US body habitus changes, proportional overestimation of the maximum safe collection volume may become clinically significant with large\u2010volume collections. We correlated 2 years of vasovagal reaction (VVR) data with 148,416 Trima apheresis procedure parameters to identify trends.<\/jats:p><\/jats:sec><jats:sec><jats:title>STUDY DESIGN AND METHODS<\/jats:title><jats:p>Only platelet\/plasma with or without red blood cell (RBC) procedures yielded collection volumes of at least 900 mL with no saline replacement. Vasovagal events of any severity were correlated by sex with actual collection volume and donor estimated blood volume (EBV). We performed multivariable analysis incorporating the factors that influence VVR rates to assess the significance of EBV and collection volume.<\/jats:p><\/jats:sec><jats:sec><jats:title>RESULTS<\/jats:title><jats:p>VVR rates nearly doubled in male donors who had collection volumes greater than 1050 mL. No reaction threshold could be identified in female donors. This was confirmed in multivariable analysis that included donor sex, age, donation experience, draw time, and reporting location.<\/jats:p><\/jats:sec><jats:sec><jats:title>CONCLUSION<\/jats:title><jats:p>Limiting apheresis collections to the lesser of 1050 mL or 15% EBV may reduce VVR rates. Further confirmation of this finding by other collection centers is desirable.<\/jats:p><\/jats:sec>","DOI":"10.1111\/trf.13897","type":"journal-article","created":{"date-parts":[[2016,11,15]],"date-time":"2016-11-15T14:40:40Z","timestamp":1479220840000},"page":"319-324","source":"Crossref","is-referenced-by-count":5,"title":["Improved donor safety in high\u2010volume apheresis collections"],"prefix":"10.1111","volume":"57","author":[{"given":"Ralph R.","family":"Vassallo","sequence":"first","affiliation":[{"name":"From Blood Systems, Inc. Scottsdale Arizona"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marjorie D.","family":"Bravo","sequence":"additional","affiliation":[{"name":"From Blood Systems, Inc. Scottsdale Arizona"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hany","family":"Kamel","sequence":"additional","affiliation":[{"name":"From Blood Systems, Inc. Scottsdale Arizona"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,11,10]]},"reference":[{"key":"e_1_2_8_2_1","article-title":"Anthropometric reference data for children and adults: United States, 2007\u20102010. National Center for Health Statistics","volume":"11","author":"Fryar CD","year":"2012","journal-title":"Vital Health Stat"},{"key":"e_1_2_8_3_1","first-page":"224","article-title":"Prediction of blood volume in normal human adults","volume":"51","author":"Nadler SR","year":"1962","journal-title":"Surgery"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1537-2995.2007.01619.x"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.56.4.605"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.transci.2008.06.007"},{"key":"e_1_2_8_7_1","unstructured":"Knowledge Based Systems Inc. Donor Hemovigilance Analysis & Reporting Tool. User Manual version 2.0 [cited 2016 Sept 14. Available from:https:\/\/www.aabb.org\/research\/hemovigilance\/Documents\/biovigilancemanual.pdf."},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1537-2995.2009.02397.x"}],"container-title":["Transfusion"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Ftrf.13897","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/trf.13897","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/trf.13897","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/trf.13897","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,22]],"date-time":"2023-08-22T06:12:57Z","timestamp":1692684777000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/trf.13897"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,11,10]]},"references-count":7,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2017,2]]}},"alternative-id":["10.1111\/trf.13897"],"URL":"https:\/\/doi.org\/10.1111\/trf.13897","archive":["Portico"],"relation":{},"ISSN":["0041-1132","1537-2995"],"issn-type":[{"value":"0041-1132","type":"print"},{"value":"1537-2995","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,11,10]]}}}