{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,5]],"date-time":"2026-03-05T12:22:20Z","timestamp":1772713340231,"version":"3.50.1"},"reference-count":29,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2017,6,22]],"date-time":"2017-06-22T00:00:00Z","timestamp":1498089600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100000014","name":"Canadian Blood Services","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000014","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000024","name":"Canadian Institutes of Health Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Transfusion"],"published-print":{"date-parts":[[2017,9]]},"abstract":"<jats:sec><jats:title>BACKGROUND<\/jats:title><jats:p>Transfusion data for obstetric patients are scarce. Identifying characteristics associated with red blood cell transfusion (RBCT) is of importance to better identify patients who would benefit from blood conservation strategies as the risk of alloimmunization from RBCT has the potential to affect the fetus and newborn.<\/jats:p><\/jats:sec><jats:sec><jats:title>STUDY DESIGN AND METHODS<\/jats:title><jats:p>We conducted a retrospective cohort study using hospital administrative data to identify trends and risk factors of RBCT in obstetric patients. Data were analyzed according to the mode of delivery.<\/jats:p><\/jats:sec><jats:sec><jats:title>RESULTS<\/jats:title><jats:p>A total of 45,213 deliveries were captured between January 1, 2007, and December 31, 2013. A higher proportion of patients undergoing cesarean sections (C\/Ss) received an RBCT (2.3%) compared to other modes of delivery (0.7% for spontaneous vaginal delivery, 1.5% for instrumental delivery; p<jats:italic>\u00a0&lt;\u00a0<\/jats:italic>0.001). In addition, the risk of RBCT increased over the 7\u2010year period for those patients undergoing C\/S (relative risk [RR], 1.56; 95% confidence interval [CI], 1.14\u20102.15). An unavailable hemoglobin (Hb) level (RR, 12.94; 95% CI, 7.39\u201022.66) and Hb level of 70 to 80 g\/L (RR, 7.78; 95% CI\u00a0= 5.21\u201011.60) were strongly associated with RBCT among women undergoing C\/S. Earlier gestational age at induction increased the risk of RBCT across all modes of delivery.<\/jats:p><\/jats:sec><jats:sec><jats:title>CONCLUSIONS<\/jats:title><jats:p>The higher frequency of RBCT for unknown and low Hb supports the need for predelivery patient blood management at the time of delivery. The additional risk factors associated with RBCT identified may be used to develop risk stratification tools by mode of delivery to assist in the identification of patients at the highest risk of requiring RBCT.<\/jats:p><\/jats:sec>","DOI":"10.1111\/trf.14184","type":"journal-article","created":{"date-parts":[[2017,6,23]],"date-time":"2017-06-23T03:40:52Z","timestamp":1498189252000},"page":"2197-2205","source":"Crossref","is-referenced-by-count":18,"title":["Risks and trends of red blood cell transfusion in obstetric patients: a retrospective study of 45,213 deliveries using administrative data"],"prefix":"10.1111","volume":"57","author":[{"given":"Nadine","family":"Shehata","sequence":"first","affiliation":[{"name":"Departments of Medicine and Laboratory Medicine and Pathobiology Institute of Health Policy Management and Evaluation, University of Toronto, Division of Hematology, Mount Sinai Hospital Toronto Ontario Canada"},{"name":"Canadian Blood Services Toronto Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Micha\u00ebl","family":"Chass\u00e9","sequence":"additional","affiliation":[{"name":"Clinical Epidemiology Program, Ottawa Hospital Research Institute Ottawa Ontario Canada"},{"name":"Department of Medicine Universit\u00e9 de Montr\u00e9al Montr\u00e9al Qu\u00e9bec Canada"},{"name":"Centre de Recherche du Centre Hospitalier Universitaire de Montr\u00e9al Montr\u00e9al Qu\u00e9bec Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jo Ann","family":"Colas","sequence":"additional","affiliation":[{"name":"Clinical Epidemiology Program, Ottawa Hospital Research Institute Ottawa Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Malia","family":"Murphy","sequence":"additional","affiliation":[{"name":"Clinical Epidemiology Program, Ottawa Hospital Research Institute Ottawa Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alan J.","family":"Forster","sequence":"additional","affiliation":[{"name":"Clinical Epidemiology Program, Ottawa Hospital Research Institute Ottawa Ontario Canada"},{"name":"Department of Medicine University of Ottawa Ottawa Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ann K.","family":"Malinowski","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology University of Toronto, Division of Maternal Fetal Medicine, Mount Sinai Hospital Toronto Ontario"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robin","family":"Ducharme","sequence":"additional","affiliation":[{"name":"Institute for Clinical Evaluative Sciences Ottawa Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dean A.","family":"Fergusson","sequence":"additional","affiliation":[{"name":"Clinical Epidemiology Program, Ottawa Hospital Research Institute Ottawa Ontario Canada"},{"name":"Department of Medicine University of Ottawa Ottawa Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alan","family":"Tinmouth","sequence":"additional","affiliation":[{"name":"Clinical Epidemiology Program, Ottawa Hospital Research Institute Ottawa Ontario Canada"},{"name":"Department of Medicine University of Ottawa Ottawa Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kumanan","family":"Wilson","sequence":"additional","affiliation":[{"name":"Clinical Epidemiology Program, Ottawa Hospital Research Institute Ottawa Ontario Canada"},{"name":"Department of Medicine University of Ottawa Ottawa Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,6,22]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/trf.13151"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2008.01984.x"},{"key":"e_1_2_8_4_1","unstructured":"Anemia in pregnancy [Internet].Rockville (MD):American College of Obstetrics and Gynecology; 2008 [cited 2017 Apr 5]. 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