{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T13:58:32Z","timestamp":1792418312349,"version":"4.4.0"},"reference-count":16,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2018,7,8]],"date-time":"2018-07-08T00:00:00Z","timestamp":1531008000000},"content-version":"vor","delay-in-days":7,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Transfusion"],"published-print":{"date-parts":[[2018,7]]},"abstract":"<jats:sec><jats:title>BACKGROUND<\/jats:title><jats:p>Suspected transfusion reaction (STR) investigations are foundational for biovigilance. Diagnostic evaluations performed by blood banks may prolong turnaround times (TATs) for final STR results reporting. We identified a quality improvement opportunity using diagnostic testing reflex algorithms and our hospital's patient electronic health record to enhance TATs regarding one aspect of STR results reporting.<\/jats:p><\/jats:sec><jats:sec><jats:title>STUDY DESIGN AND METHODS<\/jats:title><jats:p>We conducted a descriptive quality improvement study of reported STR cases investigated by our hospital's blood bank from March 1, 2014, to December 31, 2016, using data obtained from consult reports\/quality improvement databases examining the number and types of diagnostic algorithm reflex activations performed and the TATs for an electronic provisional diagnosis reporting (PDXR) related to them.<\/jats:p><\/jats:sec><jats:sec><jats:title>RESULTS<\/jats:title><jats:p>A total of 461 STR events occurred during the study interval, of which 150 involved no reflex testing. In the remainder of cases (n\u2009=\u2009311), a total of 448 reflex activations occurred. In those cases in which PDXR occurred (n\u2009=\u2009446), the median PDXR TAT during the first month of implementation was 325 minutes, which progressively decreased to 70 minutes or less approximately 1 year after implementation. By the last quarter of 2015, median TATs were 60 minutes or less in length, where they remained for the duration of the study.<\/jats:p><\/jats:sec><jats:sec><jats:title>CONCLUSION<\/jats:title><jats:p>Technologists using targeted diagnostic reflex arcs to expedite laboratory testing along with STR electronic PDXR improve communication and timely results\/information dissemination, potentially aiding bedside hemotherapy\u2010related clinical decision making.<\/jats:p><\/jats:sec>","DOI":"10.1111\/trf.14769","type":"journal-article","created":{"date-parts":[[2018,7,9]],"date-time":"2018-07-09T06:14:33Z","timestamp":1531116873000},"page":"1708-1717","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Enhancing hemotherapy safety through pertinent diagnostic testing and electronic \u201cprovisional diagnosis\u201d reporting: expanding roles for blood bank technologists in biovigilance and patient safety"],"prefix":"10.1111","volume":"58","author":[{"suffix":"Jr","given":"Chester","family":"Andrzejewski","sequence":"first","affiliation":[{"name":"Transfusion Medicine Service Baystate Medical Center, Baystate Health Springfield Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lynne","family":"O'Hearn","sequence":"additional","affiliation":[{"name":"Transfusion Medicine Service Baystate Medical Center, Baystate Health Springfield Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joan","family":"Rock","sequence":"additional","affiliation":[{"name":"Transfusion Medicine Service Baystate Medical Center, Baystate Health Springfield Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kelly","family":"Passanisi","sequence":"additional","affiliation":[{"name":"Transfusion Medicine Service Baystate Medical Center, Baystate Health Springfield Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lynn","family":"Eaton","sequence":"additional","affiliation":[{"name":"Department of Pathology Baystate Medical Center, Baystate Health Springfield Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander","family":"Knee","sequence":"additional","affiliation":[{"name":"Office of Research University of Massachusetts Medical School\u2010Baystate, Baystate Medical Center, Baystate Health Springfield Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susmitha","family":"Edappallath","sequence":"additional","affiliation":[{"name":"Department of Pathology Baystate Medical Center, Baystate Health Springfield Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Merola","sequence":"additional","affiliation":[{"name":"Transfusion Medicine Service Baystate Medical Center, Baystate Health Springfield Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Darlene","family":"Cloutier","sequence":"additional","affiliation":[{"name":"Department of Pathology Baystate Medical Center, Baystate Health Springfield Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul","family":"Visintainer","sequence":"additional","affiliation":[{"name":"Office of Research University of Massachusetts Medical School\u2010Baystate, Baystate Medical Center, Baystate Health Springfield Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vandita","family":"Johari","sequence":"additional","affiliation":[{"name":"Department of Pathology Baystate Medical Center, Baystate Health Springfield Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,7,8]]},"reference":[{"key":"e_1_2_7_2_1","first-page":"813","volume-title":"Transfusion therapy: clinical principles and practice","author":"Mintz PD.","year":"2011"},{"key":"e_1_2_7_3_1","volume-title":"Standards for blood banks and transfusion services","author":"Ooley PW","year":"2015"},{"key":"e_1_2_7_4_1","first-page":"569","volume-title":"Technical manual","author":"Savage WJ","year":"2017"},{"key":"e_1_2_7_5_1","first-page":"551","volume-title":"Transfusion reactions","author":"Andrzejewski C","year":"2012"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjh.12017"},{"key":"e_1_2_7_7_1","unstructured":"\u201cOne size does not fit all\u201d: Approaches from different sized hospitals for transfusion reaction reporting (#109). AABB eCast July 25 2017."},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/vox.12057"},{"key":"e_1_2_7_9_1","first-page":"99","volume-title":"Transfusion reactions","author":"Vamvakas EC.","year":"2012"},{"key":"e_1_2_7_10_1","doi-asserted-by":"crossref","DOI":"10.4103\/2153-3539.65345","article-title":"Development of electronic medical record charting for hospital\u2010based transfusion and apheresis medicine services: early adoption perspectives","volume":"1","author":"Levy R","year":"2010","journal-title":"J Pathol Inform"},{"key":"e_1_2_7_11_1","first-page":"22S","article-title":"Survey of vital sign changes in patients undergoing uncomplicated transfusions","volume":"42","author":"Andrzejewski C","year":"2002","journal-title":"Transfusion"},{"key":"e_1_2_7_12_1","first-page":"36","article-title":"Vital sign changes in patients undergoing platelet transfusion therapy","volume":"18","author":"Stec T","year":"2004","journal-title":"J Clin Apher"},{"key":"e_1_2_7_13_1","volume-title":"Statistical analysis of vital sign value changes in patients undergoing uncomplicated transfusions","author":"Andrzejewski C"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1537-2995.2012.03595.x"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/trf.13060"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1537-2995.2001.41121486.x"},{"key":"e_1_2_7_17_1","first-page":"39","article-title":"Improving patient safety in transfusion medicine: contemporary challenges and the roles for bedside and laboratory biovigilance in addressing them","volume":"2","author":"Andrzejewski C","year":"2014","journal-title":"Int J Clin Transfus Med"}],"container-title":["Transfusion"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Ftrf.14769","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/trf.14769","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/trf.14769","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/trf.14769","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,9]],"date-time":"2023-09-09T22:40:38Z","timestamp":1694299238000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/trf.14769"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,7]]},"references-count":16,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2018,7]]}},"alternative-id":["10.1111\/trf.14769"],"URL":"https:\/\/doi.org\/10.1111\/trf.14769","archive":["Portico"],"relation":{},"ISSN":["0041-1132","1537-2995"],"issn-type":[{"value":"0041-1132","type":"print"},{"value":"1537-2995","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,7]]},"assertion":[{"value":"2017-12-20","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-02-16","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-07-08","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}