{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T16:32:52Z","timestamp":1772987572799,"version":"3.50.1"},"reference-count":26,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2018,9,27]],"date-time":"2018-09-27T00:00:00Z","timestamp":1538006400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2018,9,27]],"date-time":"2018-09-27T00:00:00Z","timestamp":1538006400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Transfusion"],"published-print":{"date-parts":[[2018,11]]},"abstract":"<jats:sec>\n                    <jats:title>BACKGROUND<\/jats:title>\n                    <jats:p>\n                      The risk for tickborne exposure to\n                      <jats:italic>Babesia microti<\/jats:italic>\n                      infection exists statewide in Massachusetts. Broad exposure complicates investigations of transfusion\u2010transmitted babesiosis (TTB). We summarize 8 years of the epidemiology of TTB and highlight the role of public health in prevention and control.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>STUDY DESIGN AND METHODS<\/jats:title>\n                    <jats:p>Cases of babesiosis are routinely reported to the Massachusetts Department of Public Health. These are investigated to determine whether they meet the surveillance case definition and to identify whether they were potentially transfusion transmitted. Frequencies from 2009 to 2016 are described and incidence rates calculated using population denominators from the US census. Changes over time were analyzed using simple linear regression.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS<\/jats:title>\n                    <jats:p>\n                      From 2009 to 2016, there were 2578 cases of babesiosis reported; of these, 45 (1.7%) were transfusion transmitted. Of the 45 cases of TTB, 15 (33%) received blood products from two or more suppliers. In 11 TTB cases, the Department of Public Health was notified first, who in turn notified the appropriate blood provider. In 2009, the crude rate of reported babesiosis was 1.2 per 100,000 population and increased significantly through 2016 to 7.8 per 100,000 population (p = 0.006). The number of blood donors reported with laboratory evidence of\n                      <jats:italic>B. microti<\/jats:italic>\n                      infection increased from 19 in 2012 to 78 in 2016; at the same time, the number of TTB cases decreased from six to three.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSION<\/jats:title>\n                    <jats:p>TTB remains a major challenge, and blood donor screening strategies are currently in the process of implementation. While population and environmental changes facilitate increases in babesiosis, donor screening has the potential to eliminate TTB.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/trf.14943","type":"journal-article","created":{"date-parts":[[2018,9,27]],"date-time":"2018-09-27T10:38:13Z","timestamp":1538044693000},"page":"2611-2616","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Transfusion\u2010transmitted babesiosis: one state's experience"],"prefix":"10.1111","volume":"58","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2073-5576","authenticated-orcid":false,"given":"R. Monina","family":"Klevens","sequence":"first","affiliation":[{"name":"Massachusetts Department of Public Health Bureau of Infectious Disease and Laboratory Sciences  Boston Massachusetts"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Melissa A.","family":"Cumming","sequence":"additional","affiliation":[{"name":"Massachusetts Department of Public Health Bureau of Infectious Disease and Laboratory Sciences  Boston Massachusetts"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Evan","family":"Caten","sequence":"additional","affiliation":[{"name":"Massachusetts Department of Public Health Bureau of Infectious Disease and Laboratory Sciences  Boston Massachusetts"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Susan L.","family":"Stramer","sequence":"additional","affiliation":[{"name":"Scientific Affairs Department American Red Cross  Gaithersburg Maryland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rebecca L.","family":"Townsend","sequence":"additional","affiliation":[{"name":"Scientific Affairs Department American Red Cross  Gaithersburg Maryland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura","family":"Tonnetti","sequence":"additional","affiliation":[{"name":"Scientific Affairs Department American Red Cross  Gaithersburg Maryland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jorge","family":"Rios","sequence":"additional","affiliation":[{"name":"Biomedical Services American Red Cross, Massachusetts Region  Dedham Massachusetts"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carolyn T.","family":"Young","sequence":"additional","affiliation":[{"name":"Rhode Island Blood Center  Providence Rhode Island"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Susan","family":"Soliva","sequence":"additional","affiliation":[{"name":"Massachusetts Department of Public Health Bureau of Infectious Disease and Laboratory Sciences  Boston Massachusetts"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"suffix":"Jr","given":"Alfred","family":"DeMaria","sequence":"additional","affiliation":[{"name":"Massachusetts Department of Public Health Bureau of Infectious Disease and Laboratory Sciences  Boston Massachusetts"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,9,27]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM197010152831607"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-86-1-6"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.1976.25.784"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.1981.30.560"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.1976.25.376"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM197710132971511"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198011063031906"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.00022-10"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/MOH.0000000000000287"},{"key":"e_1_2_8_11_1","unstructured":"Massachusetts Department of Public Health. Babesiosis surveillance in Massachusetts 2015 [cited 2018 Sep 14]. Available from:https:\/\/www.mass.gov\/lists\/tick-borne-disease-surveillance-summaries-and-data#babesiosis-surveillance-data-."},{"key":"e_1_2_8_12_1","unstructured":"Massachusetts Department of Public Health. Surveillance summaries and data [accessed 2017 October 23]. Available from:https:\/\/www.mass.gov\/lists\/tick-borne-disease-surveillance-summaries-and-data#babesiosis-surveillance-data-."},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/trf.13872"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1177\/003335491412900206"},{"key":"e_1_2_8_15_1","unstructured":"Centers for Disease Control and Prevention. National notifiable diseases surveillance system.Babesiaspp. case definition [cited 2017 Oct 23]. Available from:https:\/\/wwwn.cdc.gov\/nndss\/conditions\/babesiosis\/case-definition\/2011."},{"key":"e_1_2_8_16_1","unstructured":"US Census Bureau. American FactFinder. Annual estimates of the resident population [cited 2017 Dec 27]. Available from:https:\/\/factfinder.census.gov\/faces\/tableservices\/jsf\/pages\/productview.xhtml?src=CF."},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1600897"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.mm6354a1"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/trf.14476"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0140332"},{"key":"e_1_2_8_21_1","article-title":"Planning for the silver tsunami","volume":"16","author":"Rensky H","year":"2014","journal-title":"MassBenchmarks"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1089\/vbz.2015.1912"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tmrv.2016.04.002"},{"key":"e_1_2_8_24_1","unstructured":"US Food and Drug Administration. 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