{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,29]],"date-time":"2026-08-29T14:19:53Z","timestamp":1788013193558,"version":"build-2784847793"},"reference-count":16,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2018,11,20]],"date-time":"2018-11-20T00:00:00Z","timestamp":1542672000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Transfusion"],"published-print":{"date-parts":[[2019,1]]},"abstract":"<jats:sec><jats:title>BACKGROUND<\/jats:title><jats:p>Transfusion\u2010associated circulatory overload (TACO) is a growing concern in clinical practice.<\/jats:p><\/jats:sec><jats:sec><jats:title>STUDY DESIGN AND METHODS<\/jats:title><jats:p>A case control study was performed at the N\u00eemes University Hospital, France. TACO cases occurring after RBC transfusion reported from January 1, 2014, to May 31, 2017, were included as cases. Four controls by case were randomly selected among the other RBC recipients on the same day.<\/jats:p><\/jats:sec><jats:sec><jats:title>RESULTS<\/jats:title><jats:p>During the study period, 60 TACO diagnoses were reported for 37,029 transfused RBCs to a total of 8787 patients; 240 controls were included. The average rate of TACO was one case every 616 RBCs transfused. One in 146 transfused patients experienced TACO. TACO was associated with a higher 28\u2010day mortality (22% vs. 11%; p = 0.003), and a longer hospital stay compared with controls (23.5 \u00b1 19.6 days vs. 15.9 \u00b1 20.1 days; p &lt; 0.001). Four risk factors were independently associated with TACO in multivariable analysis: chronic use of loop diuretics (odds ratio [OR],  6.5, 95% confidence interval [CI], 3.3\u201312.9), hemorrhagic shock (OR,  12; 95% CI, 2.9\u201350), body weight &lt;46 kg (OR,  7.9; 95% CI, 2.3\u201326.8) and chronic hypertension (OR,  4.1; 95% CI, 2\u20138.5).<\/jats:p><\/jats:sec><jats:sec><jats:title>CONCLUSION<\/jats:title><jats:p>TACO was frequent and associated with poor outcome. Four independent risk factors were identified: hemorrhagic shock, low body weight, chronic use of diuretics, and chronic hypertension.<\/jats:p><\/jats:sec>","DOI":"10.1111\/trf.15040","type":"journal-article","created":{"date-parts":[[2018,11,20]],"date-time":"2018-11-20T08:42:10Z","timestamp":1542703330000},"page":"191-195","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Outcomes and risk factors of transfusion\u2010associated circulatory overload: a case control study"],"prefix":"10.1111","volume":"59","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1563-807X","authenticated-orcid":false,"given":"Aur\u00e9lien","family":"Daurat","sequence":"first","affiliation":[{"name":"Division Anesth\u00e9sie R\u00e9animation Urgences Douleur, Centre Hospitalier Universitaire de N\u00eemes  N\u00eemes France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jessie","family":"Grenie","sequence":"additional","affiliation":[{"name":"Division Anesth\u00e9sie R\u00e9animation Urgences Douleur, Centre Hospitalier Universitaire de N\u00eemes  N\u00eemes France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claire","family":"Roger","sequence":"additional","affiliation":[{"name":"Division Anesth\u00e9sie R\u00e9animation Urgences Douleur, Centre Hospitalier Universitaire de N\u00eemes  N\u00eemes France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G\u00e9rald","family":"Daurat","sequence":"additional","affiliation":[{"name":"D\u00e9l\u00e9gation Qualit\u00e9 et Gestion des Risques Centre Hospitalier Universitaire de N\u00eemes  N\u00eemes France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philippe","family":"Cuvillon","sequence":"additional","affiliation":[{"name":"Division Anesth\u00e9sie R\u00e9animation Urgences Douleur, Centre Hospitalier Universitaire de N\u00eemes  N\u00eemes France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laurent","family":"Muller","sequence":"additional","affiliation":[{"name":"Division Anesth\u00e9sie R\u00e9animation Urgences Douleur, Centre Hospitalier Universitaire de N\u00eemes  N\u00eemes France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean Yves","family":"Lefrant","sequence":"additional","affiliation":[{"name":"Division Anesth\u00e9sie R\u00e9animation Urgences Douleur, Centre Hospitalier Universitaire de N\u00eemes  N\u00eemes France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,11,20]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1537-2995.2010.02851.x"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tmrv.2013.07.002"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/vox.12367"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/ALN.0000000000000513"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjmed.2012.08.019"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/vox.12070"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/ALN.0000000000001506"},{"key":"e_1_2_7_9_1","unstructured":"SHOT Annual Reports and Summaries [Internet]. Serious hazards of transfusion. [cited 2017 Dec 14]. Available fromhttps:\/\/www.shotuk.org\/shot-reports\/."},{"key":"e_1_2_7_10_1","unstructured":"Rapports\/Synth\u00e8ses \u2010 Produits sanguins labiles \/ M\u00e9dicaments d\u00e9riv\u00e9s du sang [Blood\u2010derived drugs] \u2010 ANSM: Agence nationale de s\u00e9curit\u00e9 du m\u00e9dicament et des produits de Sante [National Agency for the Safety of Medicines and Health Products [Internet]. [cited 2017 Aug 24] Available fromhttp:\/\/ansm.sante.fr\/Mediatheque\/Publications\/Rapports-Syntheses-Produits-sanguins-labiles-Medicaments-derives-du-sang#mds."},{"key":"e_1_2_7_11_1","unstructured":"Transfusion\u2010associated circulatory overload (TACO) \u2010 draft revised reporting criteria \u2010 TACO\u2010reporting\u2010criteria\u2010draft\u2010Nov\u20102016.pdf [Internet] [cited 2018 Jan 12] Available fromhttps:\/\/www.aabb.org\/research\/hemovigilance\/Documents\/TACO-reporting-criteria-draft-Nov-2016.pdf."},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/trf.13475"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tracli.2014.07.008"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/trf.12965"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1537-2995.2010.02816.x"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/vox.12560"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.3109\/07853890.2012.660493"}],"container-title":["Transfusion"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Ftrf.15040","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/trf.15040","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/trf.15040","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/trf.15040","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,10]],"date-time":"2023-09-10T12:11:33Z","timestamp":1694347893000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/trf.15040"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,11,20]]},"references-count":16,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2019,1]]}},"alternative-id":["10.1111\/trf.15040"],"URL":"https:\/\/doi.org\/10.1111\/trf.15040","archive":["Portico"],"relation":{},"ISSN":["0041-1132","1537-2995"],"issn-type":[{"value":"0041-1132","type":"print"},{"value":"1537-2995","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,11,20]]},"assertion":[{"value":"2018-02-19","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-09-10","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-11-20","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}