{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T02:07:10Z","timestamp":1747188430741,"version":"3.40.5"},"reference-count":12,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2019,9,10]],"date-time":"2019-09-10T00:00:00Z","timestamp":1568073600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Transfusion"],"published-print":{"date-parts":[[2019,11]]},"abstract":"<jats:sec><jats:title>BACKGROUND<\/jats:title><jats:p>Mt<jats:sup>a<\/jats:sup> (MNS14) is a low\u2010prevalence antigen of the MNS system. A few cases of hemolytic disease of the fetus and newborn caused by anti\u2010Mt<jats:sup>a<\/jats:sup> have been reported in the literature, but up to now this antibody has never been associated with a hemolytic transfusion reaction (HTR).<\/jats:p><\/jats:sec><jats:sec><jats:title>CASE REPORT<\/jats:title><jats:p>A 38\u2010year\u2010old male with sickle cell disease undergoing exchange transfusion presented with shivering, nausea, dyspnea, and pain in the lower limbs. Biologic parameters showed increased hemolysis. The administered red blood cell (RBC) units had been issued by electronic crossmatch due to a negative antibody screening test. In the posttransfusion investigations, crossmatch of the transfused RBC units with the patient's serum showed incompatibility of one unit. The presence of an antibody against a low\u2010prevalence antigen was suspected and further serologic testing was performed for identification.<\/jats:p><\/jats:sec><jats:sec><jats:title>RESULTS<\/jats:title><jats:p>Anti\u2010Mt<jats:sup>a<\/jats:sup> was identified in the patient's serum. The RBCs of the incompatible unit implicated in the HTR were Mt(a+). An eluate of a posttransfusion blood sample of the patient was nonreactive with the incompatible RBCs, and the direct antiglobulin test was negative.<\/jats:p><\/jats:sec><jats:sec><jats:title>CONCLUSION<\/jats:title><jats:p>To our knowledge, this is the first case report of an HTR associated with anti\u2010Mt<jats:sup>a<\/jats:sup>.<\/jats:p><\/jats:sec>","DOI":"10.1111\/trf.15521","type":"journal-article","created":{"date-parts":[[2019,9,10]],"date-time":"2019-09-10T14:54:28Z","timestamp":1568127268000},"page":"3314-3318","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Acute hemolytic transfusion reaction associated with anti\u2010Mt<sup>a<\/sup>: case report and review of the literature"],"prefix":"10.1111","volume":"59","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6398-4009","authenticated-orcid":false,"given":"Vincent","family":"Claes","sequence":"first","affiliation":[{"name":"Blood Bank \u2013 Laboratory of Immunohematology, Centre Hospitalier Universitaire Brugmann Laboratoire Hospitalier Universitaire de Bruxelles (LHUB)  Brussels Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7715-568X","authenticated-orcid":false,"given":"Thierry","family":"Peyrard","sequence":"additional","affiliation":[{"name":"Centre National de R\u00e9f\u00e9rence pour les Groupes Sanguins (CNRGS) Institut National de la Transfusion Sanguine (INTS)  Paris France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marie","family":"Deleers","sequence":"additional","affiliation":[{"name":"Blood Bank \u2013 Laboratory of Immunohematology, Centre Hospitalier Universitaire Brugmann Laboratoire Hospitalier Universitaire de Bruxelles (LHUB)  Brussels Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hanane","family":"El Kenz","sequence":"additional","affiliation":[{"name":"Blood Bank \u2013 Laboratory of Immunohematology, Centre Hospitalier Universitaire Brugmann Laboratoire Hospitalier Universitaire de Bruxelles (LHUB)  Brussels Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,9,10]]},"reference":[{"doi-asserted-by":"publisher","key":"e_1_2_9_2_1","DOI":"10.1111\/j.1423-0410.1962.tb04288.x"},{"doi-asserted-by":"publisher","key":"e_1_2_9_3_1","DOI":"10.1111\/j.1423-0410.1972.tb03990.x"},{"doi-asserted-by":"publisher","key":"e_1_2_9_4_1","DOI":"10.21307\/immunohematology-2019-506"},{"doi-asserted-by":"publisher","key":"e_1_2_9_5_1","DOI":"10.21307\/immunohematology-2019-619"},{"doi-asserted-by":"publisher","key":"e_1_2_9_6_1","DOI":"10.1111\/j.1423-0410.1965.tb04338.x"},{"doi-asserted-by":"publisher","key":"e_1_2_9_7_1","DOI":"10.1111\/j.1423-0410.1963.tb04192.x"},{"doi-asserted-by":"publisher","key":"e_1_2_9_8_1","DOI":"10.1111\/j.1537-2995.1967.tb05516.x"},{"volume-title":"Blood groups in 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