{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,15]],"date-time":"2025-11-15T10:25:40Z","timestamp":1763202340414,"version":"3.40.5"},"reference-count":26,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2020,1,8]],"date-time":"2020-01-08T00:00:00Z","timestamp":1578441600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"publisher","award":["HHSN2682011000081"],"award-info":[{"award-number":["HHSN2682011000081"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Transfusion"],"published-print":{"date-parts":[[2020,2]]},"abstract":"<jats:sec><jats:title>BACKGROUND<\/jats:title><jats:p>In China, there is a rising concern on the increasing trends of HIV infections in high\u2010risk groups, who make blood donations that might potentially challenge the blood safety. Analyses on current risk factors for HIV infection among Chinese blood donors are urgently needed for developing effective strategies to defer high\u2010risk donors and to warrant the safety of the blood supply.<\/jats:p><\/jats:sec><jats:sec><jats:title>STUDY DESIGN AND METHODS<\/jats:title><jats:p>We recruited 313 HIV\u2010positive and 762 HIV\u2010negative donors from seven study sites in China and evaluated donor demographic characteristics, current medical and behavioral risk factors associated with HIV infection in a case\u2013control survey. Univariable analyses examined the relationship between HIV infection and donor and donation characteristics, medical and behavioral risks, living conditions, and lifestyles. Multivariable logistic regression analyses evaluated the association between selected individual risks and HIV infection. Regression tree analysis was used to select covariates correlated with both HIV infection and individual risks and thus need to be controlled for in logistic regression models.<\/jats:p><\/jats:sec><jats:sec><jats:title>RESULTS<\/jats:title><jats:p>Being a man who has sex with men was associated with the highest odds of HIV infection. Not using a condom, having sex with HIV\u2010infected individuals, having sex partners with sexually transmitted diseases (STDs), having more than two concurrent sex partners, or having an STD were all associated with more than five times higher odds of having HIV. Having remunerated sex was associated with a 2.4 increased odds of having HIV infection.<\/jats:p><\/jats:sec><jats:sec><jats:title>CONCLUSION<\/jats:title><jats:p>High\u2010risk sexual behaviors were among the major risks for HIV infection among Chinese blood donors.<\/jats:p><\/jats:sec>","DOI":"10.1111\/trf.15659","type":"journal-article","created":{"date-parts":[[2020,1,8]],"date-time":"2020-01-08T12:52:31Z","timestamp":1578487951000},"page":"326-333","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Current risk factors for HIV infection among blood donors in seven Chinese regions"],"prefix":"10.1111","volume":"60","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6668-2380","authenticated-orcid":false,"given":"Peibin","family":"Zeng","sequence":"first","affiliation":[{"name":"West China School of Public Health and West China Fourth Hospital Sichuan University  Chengdu Sichuan China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jing","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Pathology Johns Hopkins Medical Institutions  Baltimore Maryland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chunhong","family":"Zhang","sequence":"additional","affiliation":[{"name":"Chongqing Blood Center  Chongqing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bowei","family":"Zhang","sequence":"additional","affiliation":[{"name":"Henan Provincial Blood Center  Zhenzhou Henan China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei","family":"Liu","sequence":"additional","affiliation":[{"name":"Guangxi Center for Disease Prevention and Control  Nanning Guangxi China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mei","family":"Huang","sequence":"additional","affiliation":[{"name":"Mianyang Blood Center  Mianyang Sichuan China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hongli","family":"Ma","sequence":"additional","affiliation":[{"name":"Luoyang Blood Center  Luoyang Henan China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuwei","family":"Zhao","sequence":"additional","affiliation":[{"name":"Chengdu Blood Center  Chengdu Sichuan China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rong","family":"Guo","sequence":"additional","affiliation":[{"name":"Xinjiang Provincial Blood Center  Urumqi Xinjiang China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miao","family":"He","sequence":"additional","affiliation":[{"name":"Institute of Blood Transfusion Chinese Academic of Medical Science  Chengdu Sichuan China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yu","family":"Liu","sequence":"additional","affiliation":[{"name":"Institute of Blood Transfusion Chinese Academic of Medical Science  Chengdu Sichuan China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dan","family":"Liao","sequence":"additional","affiliation":[{"name":"RTI International  Research Triangle Park North Carolina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marian","family":"Sullivan","sequence":"additional","affiliation":[{"name":"RTI International  Research Triangle Park North Carolina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jingxing","family":"Wang","sequence":"additional","affiliation":[{"name":"Institute of Blood Transfusion Chinese Academic of Medical Science  Chengdu Sichuan China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei","family":"Cai","sequence":"additional","affiliation":[{"name":"Department of Pathology Stanford University  Palo Alto California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul","family":"Ness","sequence":"additional","affiliation":[{"name":"Department of Pathology Johns Hopkins Medical Institutions  Baltimore Maryland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hua","family":"Shan","sequence":"additional","affiliation":[{"name":"Department of Pathology Stanford University  Palo Alto California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"for the International Component of the NHLBI Recipient Epidemiology and Donor Evaluation Study\u2010III (REDS\u2010III)","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,1,8]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tmrv.2016.11.001"},{"key":"e_1_2_7_3_1","unstructured":"National Health and Family Planning Commission of the People\u02bcs Republic of China. 2015 China AIDS response progress report. [cited 2019 Mar 12]. Available from:http:\/\/www.unaids.org\/sites\/default\/files\/country\/documents\/CHN_narrative_report_2015.pdf."},{"key":"e_1_2_7_4_1","first-page":"173","article-title":"Comparative clinical evaluation of mini\u2010pool NAT and individual donor NAT by PROCLEIX ULTRIO assay for donation screening","volume":"23","author":"Song M","year":"2010","journal-title":"Chin J Blood Transfus"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3156.2012.03019.x"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1080\/09540121.2010.507759"},{"key":"e_1_2_7_7_1","doi-asserted-by":"crossref","first-page":"101","DOI":"10.7555\/JBR.30.20150057","article-title":"Prevalence and risk factors of HIV and syphilis, and knowledge and risk behaviors related to HIV\/AIDS among men who have sex with men in Chongqing, China","volume":"30","author":"Ma W","year":"2016","journal-title":"J Biomed Res"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/QAI.0000000000001217"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2334-14-490"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1093\/heapro\/dav049"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10461-005-9039-5"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0097527"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(17)30711-9"},{"key":"e_1_2_7_14_1","unstructured":"Griffiths J FangN WangS. China\u02bcs lack of sex education is putting millions of young people at risk. CNN Health Dec 6 2016. [Cited 2020 Jan 4]. Available from:https:\/\/edition.cnn.com\/2016\/11\/30\/health\/china-sex-education-world-aids-day\/."},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1155\/2018\/7375831"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijid.2012.01.012"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cix031"},{"key":"e_1_2_7_18_1","unstructured":"Canadian Blood Services. Blood donation waiting period for men who have sex with men reduced to three months. 2019 [cited 2019 Nov 11]. Available from:https:\/\/blood.ca\/en\/news-and-events\/newsroom\/blood-donation-waiting-period-for-men-who-have-sex-with-men-reduced-to-three-months."},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0164761"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0950268818003023"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1097\/QAI.0000000000002174"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10900-015-0065-6"},{"key":"e_1_2_7_23_1","first-page":"72","article-title":"Sociodemographic characteristics, sexual behavior, and HIV risks of rural\u2010to\u2010urban migrants in China","volume":"1","author":"He N","year":"2007","journal-title":"Biosci Trends"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1136\/sextrans-2016-052744"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12889-015-2614-4"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.332.6035.1253"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(11)60079-2"}],"container-title":["Transfusion"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Ftrf.15659","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/trf.15659","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/trf.15659","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/trf.15659","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,5]],"date-time":"2023-09-05T03:13:10Z","timestamp":1693883590000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/trf.15659"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,1,8]]},"references-count":26,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2020,2]]}},"alternative-id":["10.1111\/trf.15659"],"URL":"https:\/\/doi.org\/10.1111\/trf.15659","archive":["Portico"],"relation":{},"ISSN":["0041-1132","1537-2995"],"issn-type":[{"type":"print","value":"0041-1132"},{"type":"electronic","value":"1537-2995"}],"subject":[],"published":{"date-parts":[[2020,1,8]]},"assertion":[{"value":"2019-07-12","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-11-26","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-01-08","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}