{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,11]],"date-time":"2026-06-11T15:31:24Z","timestamp":1781191884972,"version":"3.54.1"},"reference-count":15,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2020,6,11]],"date-time":"2020-06-11T00:00:00Z","timestamp":1591833600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Transfusion"],"published-print":{"date-parts":[[2020,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>We report a case of severe acute thrombocytopenia occurring within days after a cadaveric liver transplant, received from a female patient with aplastic anemia who died of intracranial bleeding. The donor, who was homozygous for the <jats:italic>ITGA2B*002 (HPA\u20103b)<\/jats:italic> gene, had developed human platelet antigen (HPA)\u20103a antibodies, whereas the recipient was homozygous for the <jats:italic>ITGA2B*001 (HPA\u20103a)<\/jats:italic> gene. Thrombocytopenia responded to an infusion of immunoglobulin G. This is the first report of a passenger lymphocyte syndrome manifesting with thrombocytopenia due to anti\u2010HPA\u20103a. We review the literature on thrombocytopenia in the setting of PLS and discuss the differential diagnosis.<\/jats:p>","DOI":"10.1111\/trf.15905","type":"journal-article","created":{"date-parts":[[2020,6,12]],"date-time":"2020-06-12T03:00:33Z","timestamp":1591930833000},"page":"2185-2188","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Passenger lymphocyte thrombocytopenia due to human platelet antigen 3a antibodies: Case report and review of literature"],"prefix":"10.1111","volume":"60","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0657-641X","authenticated-orcid":false,"given":"Winnifred","family":"French","sequence":"first","affiliation":[{"name":"King\u02bcs College Hospital NHS Foundation Trust  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew","family":"Hopkins","sequence":"additional","affiliation":[{"name":"National Health Service Blood and Transplant, Filton  Bristol UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anthony","family":"Poles","sequence":"additional","affiliation":[{"name":"National Health Service Blood and Transplant, Filton  Bristol UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0592-2640","authenticated-orcid":false,"given":"Aleksandar","family":"Mijovic","sequence":"additional","affiliation":[{"name":"King\u02bcs College Hospital NHS Foundation Trust  London UK"},{"name":"National Health Service Blood and Transplant, Filton  Bristol UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,6,11]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.14218\/JCTH.2016.00072"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1155\/2008\/715769"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajt.12219"},{"key":"e_1_2_5_5_1","first-page":"500","volume-title":"Immune Hemolytic Anaemias","author":"Petz LD","year":"2004"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1159\/000357985"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/TP.0000000000001669"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199911113412004"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajh.24944"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1423-0410.2007.00989.x"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-199903150-00010"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v24.i13.1386"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0887-7963(97)80095-8"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajt.14105"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1080\/10245332.2016.1240392"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.TP.0000122417.61345.2D"}],"container-title":["Transfusion"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Ftrf.15905","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/trf.15905","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/trf.15905","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/trf.15905","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,4]],"date-time":"2023-09-04T10:20:40Z","timestamp":1693822840000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/trf.15905"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,6,11]]},"references-count":15,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2020,10]]}},"alternative-id":["10.1111\/trf.15905"],"URL":"https:\/\/doi.org\/10.1111\/trf.15905","archive":["Portico"],"relation":{},"ISSN":["0041-1132","1537-2995"],"issn-type":[{"value":"0041-1132","type":"print"},{"value":"1537-2995","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,6,11]]},"assertion":[{"value":"2020-02-28","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-04-26","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-06-11","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}