{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T13:58:32Z","timestamp":1792418312415,"version":"4.4.0"},"reference-count":16,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2020,7,20]],"date-time":"2020-07-20T00:00:00Z","timestamp":1595203200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Transfusion"],"published-print":{"date-parts":[[2020,9]]},"abstract":"Abstract<\/jats:title>\n \n Background<\/jats:title>\n The study was designed to evaluate the ability of a novel electronic automatic notification system (EANS) to detect significant changes in transfusion\u2010associated vital signs (VSs) during transfusion and to determine whether the EANS improved acute transfusion reaction (ATR) detection rates and suspected ATR reporting rates.<\/jats:p>\n <\/jats:sec>\n \n Study Design and Methods<\/jats:title>\n VSs were measured three times per unit or batch product transfused:\u2014before, 15\u2009minutes after commencement, and at the completion of the transfusion\u2014and recorded on the EANS. Significant changes in VSs were defined as increased temperature (\u226538\u00b0C or \u22651\u00b0C change in baseline temperature), 20\u2009mm\u2009Hg or 20% increase or decrease in systolic blood pressure, or 20% increase in pulse rate. The 6\u2010month periods preceding and after the introduction of the EANS were defined as \u201cbefore\u201d and \u201cafter.\u201d Data from these periods were used for comparison and evaluation.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n During the after period, 945 notifications were reported from the EANS and 521 suspected ATR were detected. The suspected ATR reporting rates for the before and after were 0.29% (73\/25\u2009213) and 2.06% (521\/25\u2009304,\n P<\/jats:italic>\n \u2009<\u2009.001) and the ATR detection rates before and after were 0.13% (33\/25\u2009213) and 0.49% (116\/25\u2009304,\n P<\/jats:italic>\n \u2009<\u2009.001), respectively. Among 116 ATR cases, 49.1% could be detected only by significant changes in VSs.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n The EANS was very effective in detecting ATRs that could have been overlooked by medical staff. Further data are needed to demonstrate the extent to which the introduction of an EANS may improve the safety of transfused patients.<\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/trf.15931","type":"journal-article","created":{"date-parts":[[2020,7,20]],"date-time":"2020-07-20T08:49:44Z","timestamp":1595234984000},"page":"1950-1959","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Early recognition of possible transfusion reactions using an electronic automatic notification system for changes in vital signs in patients undergoing blood transfusions"],"prefix":"10.1111","volume":"60","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8472-289X","authenticated-orcid":false,"given":"Young Ae","family":"Lim","sequence":"first","affiliation":[{"name":"Department of Laboratory Medicine Ajou University School of Medicine Suwon South Korea"},{"name":"Department of Laboratory Medicine Ajou University Hospital Suwon South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jin","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine Ajou University Hospital Suwon South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chorong","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine Ajou University Hospital Suwon South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,7,20]]},"reference":[{"key":"e_1_2_8_2_1","first-page":"569","volume-title":"Technical Manual","author":"Savage WJ","year":"2017"},{"key":"e_1_2_8_3_1","first-page":"497","volume-title":"Technical Manual","author":"Melanie J","year":"2017"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1188\/15.CJON.516-520"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/vox.12569"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.resuscitation.2011.03.006"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/voxs.12404"},{"key":"e_1_2_8_8_1","unstructured":"U.S. Centers for Disease Control and Prevention.The National Healthcare Safety Network (NHSN) Manual: Biovigilance Component v2.2. Atlanta GA: Division of Healthcare Quality Promotion National Center for Emerging Zoonotic Infectious Diseases.http:\/\/www.cdc.gov\/nhsn\/pdfs\/biovigilance\/bv-hv-protocol-current.pdf. Accessed January 12 2020."},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/trf.13060"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1177\/107327481502200104"},{"key":"e_1_2_8_11_1","unstructured":"SuddockJT CrookstonKP.Transfusion Reactions. SourceStatPearls[Internet]. Treasure Island FL: StatPearls Publishing; 2019. [accessed 2020 Jan 13] Available fromhttps:\/\/www.statpearls.com\/as\/hematologic\/30465\/"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1537-2995.2011.03509.x"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/vox.12621"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.0041-1132.2003.00518.x"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.3343\/alm.2016.36.1.36"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1537-2995.2012.03595.x"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.17945\/kjbt.2018.29.1.51"}],"container-title":["Transfusion"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Ftrf.15931","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/trf.15931","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/trf.15931","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/trf.15931","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,4]],"date-time":"2023-09-04T18:20:59Z","timestamp":1693851659000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/trf.15931"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,7,20]]},"references-count":16,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2020,9]]}},"alternative-id":["10.1111\/trf.15931"],"URL":"https:\/\/doi.org\/10.1111\/trf.15931","archive":["Portico"],"relation":{},"ISSN":["0041-1132","1537-2995"],"issn-type":[{"value":"0041-1132","type":"print"},{"value":"1537-2995","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,7,20]]},"assertion":[{"value":"2020-03-05","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-05-25","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-07-20","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}