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Final RT\u2010PCR was negative on swab (77.0%) or blood (88.4%; <jats:italic>P<\/jats:italic> =\u2009.46). Final definition of RT\u2010PCR was only defined at more than 28\u2009days after full recovery in 59 of 174 (33.9%) RT\u2010PCR \u2013ve, and 25\/69 RT\u2010PCR\u2009+ve (36.2%; 13 between 35 and 48\u2009days). Neutralizing antibody titers of 160 or greater were found in 63.6%. Correlation between IgG signal\/cutoff of 5.0 or greater and neutralizing antibody of 160 or greater was 82.4%. Combination of final RT\u2010PCR \u2013ve with neutralizing antibody \u2265160 was 41.3% (112\/271). Serial plasma collection showed decline in neutralizing antibody titers and IgA levels (<jats:italic>P<\/jats:italic> &lt;\u2009.05), probably denoting a \u201cgolden period\u201d for CCP collection (\u226428\u2009days after joining the program); IgA might have an important role as neutralizing antibody. Donor's weight, days between disease onset and serial plasma collection, and IgG and IgM levels are important predictors for neutralizing antibody titer.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>RT\u2010PCR\u2009+ve cases are still detected in 36.2% within 28 to 48\u2009days after recovery. High anti\u2013nucleocapsid protein IgG levels may be used as a surrogate marker to neutralizing antibody.<\/jats:p><\/jats:sec>","DOI":"10.1111\/trf.16065","type":"journal-article","created":{"date-parts":[[2020,9,16]],"date-time":"2020-09-16T20:36:42Z","timestamp":1600288602000},"page":"2938-2951","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":60,"title":["Screening for <scp>SARS\u2010CoV<\/scp>\u20102 antibodies in convalescent plasma in Brazil: Preliminary lessons from a voluntary convalescent donor program"],"prefix":"10.1111","volume":"60","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1941-7733","authenticated-orcid":false,"given":"Silvano","family":"Wendel","sequence":"first","affiliation":[{"name":"Hospital S\u00edrio\u2010Liban\u00eas Blood Bank  S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jose 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