{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T16:38:56Z","timestamp":1789231136069,"version":"build-2803163510"},"reference-count":11,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2020,11,17]],"date-time":"2020-11-17T00:00:00Z","timestamp":1605571200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Transfusion"],"published-print":{"date-parts":[[2021,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The COVID\u201019 pandemic has placed great strain on blood resources. In an effort to extend platelet (PLT) shelf life and minimize waste, our institution transitioned room temperature to cold\u2010stored PLTs for administration to bleeding patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design and Methods<\/jats:title><jats:p>We describe the administrative and technical processes involved in transitioning room temperature PLTs to cold storage in April 2020. Additionally, we describe the clinical utilization of cold\u2010stored PLTs in the first month of this practice change, with a focus on changes in PLT counts after transfusion, hemostasis, and safety outcomes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 61 cold\u2010stored PLT units were transfused to 40 bleeding patients, with a median (interquartile range [IQR]) of 1 (1\u20102) units per patient. The median age was 68 (59\u201073) years; 58% male. Median pretransfusion and posttransfusion PLTs counts were 88 (67\u2010109) and 115 (93\u2010145). A total of 95% of transfusions were administered in the operating room: 57% cardiac surgery, 20% vascular surgery, 8% general surgery, and 5% solid organ transplantation. Hemostasis was deemed to be adequate in all cases after transfusion. There were no transfusion reactions. One patient (3%) experienced a fever and infection within 5\u2009days of transfusion, which was unrelated to transfusion. Median (IQR) hospital length of stay was 8.5 (6\u201017) days. Two patients (5%) died in the hospital of complications not related to transfusion.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Cold\u2010stored PLT utilization was associated with adequate hemostasis and no overt signal for patient harm. Conversion from room temperature to cold\u2010stored PLTs may be one method of reducing waste in times of scarce blood inventories.<\/jats:p><\/jats:sec>","DOI":"10.1111\/trf.16148","type":"journal-article","created":{"date-parts":[[2020,10,8]],"date-time":"2020-10-08T08:32:45Z","timestamp":1602145965000},"page":"72-77","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":47,"title":["Transition from <scp>room temperature<\/scp> to <scp>cold\u2010stored<\/scp> platelets for the preservation of blood inventories during the <scp>COVID<\/scp>\u201019 pandemic"],"prefix":"10.1111","volume":"61","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6625-8755","authenticated-orcid":false,"given":"Matthew A.","family":"Warner","sequence":"first","affiliation":[{"name":"Division of Critical Care Medicine, Department of Anesthesiology and Perioperative Medicine Mayo Clinic  Rochester\u2009 Minnesota"},{"name":"Patient Blood Management Program Mayo Clinic  Rochester Minnesota"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emil B.","family":"Kurian","sequence":"additional","affiliation":[{"name":"Mayo Clinic Alix School of Medicine Mayo Clinic  Rochester Minnesota"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Scott A.","family":"Hammel","sequence":"additional","affiliation":[{"name":"Division of Transfusion Medicine, Department of Pathology Mayo Clinic  Rochester Minnesota"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Camille M.","family":"van Buskirk","sequence":"additional","affiliation":[{"name":"Division of Transfusion Medicine, Department of Pathology Mayo Clinic  Rochester Minnesota"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daryl J.","family":"Kor","sequence":"additional","affiliation":[{"name":"Division of Critical Care Medicine, Department of Anesthesiology and Perioperative Medicine Mayo Clinic  Rochester\u2009 Minnesota"},{"name":"Patient Blood Management Program Mayo Clinic  Rochester Minnesota"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3270-4913","authenticated-orcid":false,"given":"James R.","family":"Stubbs","sequence":"additional","affiliation":[{"name":"Division of Transfusion Medicine, Department of Pathology Mayo Clinic  Rochester Minnesota"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,11,17]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1213\/ANE.0000000000004844"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.7326\/M14-1589"},{"key":"e_1_2_7_4_1","unstructured":"Blood Products Advisory Committee Meeting FDA White Oak Campus Silver Spring MD July 18 2018.Meeting Issue Summary\u2014Topic I: Strategies to Control the Risk of Bacterial Contamination in Platelets for Transfusion; Silver Spring MD: Food and Drug Administration; 2018."},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/trf.14303"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.transci.2018.12.012"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM196905152802004"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1537-2995.1973.tb05442.x"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1537-2995.1976.16176130832.x"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/SHK.0000000000000082"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/vox.12649"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/TA.0000000000002340"}],"container-title":["Transfusion"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/trf.16148","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/trf.16148","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/trf.16148","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,2]],"date-time":"2023-09-02T11:55:06Z","timestamp":1693655706000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/trf.16148"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,11,17]]},"references-count":11,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2021,1]]}},"alternative-id":["10.1111\/trf.16148"],"URL":"https:\/\/doi.org\/10.1111\/trf.16148","archive":["Portico"],"relation":{},"ISSN":["0041-1132","1537-2995"],"issn-type":[{"value":"0041-1132","type":"print"},{"value":"1537-2995","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,11,17]]},"assertion":[{"value":"2020-08-06","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-09-18","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-11-17","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}