{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,28]],"date-time":"2026-03-28T21:07:04Z","timestamp":1774732024133,"version":"3.50.1"},"reference-count":7,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2021,2,20]],"date-time":"2021-02-20T00:00:00Z","timestamp":1613779200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Transfusion"],"published-print":{"date-parts":[[2021,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>COVID\u201019 safety measures and possibly SARS\u2010CoV\u20102 antibody testing may alter blood donor demography, which has the potential to alter blood safety. We characterized pre\u2010pandemic and pandemic rates of donor infectious disease marker (IDM) reactivity which reflect the residual risk of transfusion\u2010transmitted infections (TTIs) undetectable by current testing.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This cross\u2010sectional analysis of allogeneic blood donor presentations and successful donations in a large national US blood collector identifies changes in self\u2010reported behavioral risk factors and IDM reactivity. Data on allogeneic blood donor presentations and successful donations from March 1 through August 31, 2020 and the same period in 2019 were retrieved from the blood center's computer system. Donor demographics and deferrals for reported behavioral risk factors and confirmed\u2010positive IDMs were compared in pre\u2010pandemic and pandemic periods.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>With increasing mobile blood drive cancellations, pandemic donors were more likely than 2019 donors to be female, over age 30, non\u2010Hispanic Whites, and have a post\u2010secondary degree. First\u2010time donations (at highest risk for confirmed\u2010positive IDMs) did not substantially increase. Pandemic donors reported fewer behavioral risks and IDMs declined among these donors. Mid\u2010pandemic introduction of screening for SARS\u2010CoV\u20102 antibodies did not affect IDM rates.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Unlike disasters, which tend to bring out more first\u2010time donors with increased IDM reactivity and TTI residual risk, COVID\u201019 donors had lower IDM rates which were not affected by SARS\u2010CoV\u20102 antibody testing. Already\u2010low TTI residual risk is likely to have declined as a result.<\/jats:p><\/jats:sec>","DOI":"10.1111\/trf.16320","type":"journal-article","created":{"date-parts":[[2021,2,8]],"date-time":"2021-02-08T10:46:54Z","timestamp":1612781214000},"page":"1389-1393","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Pandemic blood donor demographics \u2013 Do changes impact blood safety?"],"prefix":"10.1111","volume":"61","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8754-047X","authenticated-orcid":false,"given":"Ralph R.","family":"Vassallo","sequence":"first","affiliation":[{"name":"Vitalant Medical Affairs  Scottsdale Arizona USA"},{"name":"Department of Pathology University of NM School of Medicine  Albuquerque New Mexico USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marjorie D.","family":"Bravo","sequence":"additional","affiliation":[{"name":"Vitalant Medical Affairs  Scottsdale Arizona USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hany","family":"Kamel","sequence":"additional","affiliation":[{"name":"Vitalant Medical Affairs  Scottsdale Arizona USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,2,20]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1377\/hlthaff.2020.00608"},{"key":"e_1_2_6_3_1","article-title":"Face masks against COVID\u201019: An evidence review","volume":"118","author":"Howard J","year":"2021","journal-title":"Preprints"},{"key":"e_1_2_6_4_1","article-title":"Evidence\u2010based, cost\u2010effective interventions to suppress the COVID\u201019 pandemic: A systematic review","author":"Juneau CE","year":"2020","journal-title":"MedRxiv"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1537-2995.2004.04215.x"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tmrv.2011.07.007"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1997.03540360035027"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.289.17.2246"}],"container-title":["Transfusion"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/trf.16320","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/trf.16320","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/trf.16320","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T07:10:50Z","timestamp":1693552250000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/trf.16320"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,2,20]]},"references-count":7,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2021,5]]}},"alternative-id":["10.1111\/trf.16320"],"URL":"https:\/\/doi.org\/10.1111\/trf.16320","archive":["Portico"],"relation":{},"ISSN":["0041-1132","1537-2995"],"issn-type":[{"value":"0041-1132","type":"print"},{"value":"1537-2995","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,2,20]]},"assertion":[{"value":"2020-12-10","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-01-18","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-02-20","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}