{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T05:38:38Z","timestamp":1777441118629,"version":"3.51.4"},"reference-count":14,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2021,7,6]],"date-time":"2021-07-06T00:00:00Z","timestamp":1625529600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Transfusion"],"published-print":{"date-parts":[[2021,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Laboratory results can be affected by sample to sample carryover. Carryover of different analytes occurring in automated clinical chemistry, immunology, hematology, and molecular laboratories is well described. However, carryover in a transfusion service laboratory is not reported in medical literature.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and methods<\/jats:title><jats:p>Immunohematology testing results, demographic data, and clinical data were reviewed on three patients retrospectively from 2015 to 2019.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Type and screen samples tested on automated gel platform from two D+ patients were affected by anti\u2010D carryover from a patient sample with a very high\u2010titer anti\u2010D. Additional immunohematology and molecular testing confirmed that anti\u2010D in samples of two D+ patients was due to carryover.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>A case of anti\u2010D carryover caused false detection of anti\u2010D in two D+ patients. Carryover can have implications for patient management. Transfusion laboratory staff need to be aware of it and investigate any unexpected results further.<\/jats:p><\/jats:sec>","DOI":"10.1111\/trf.16578","type":"journal-article","created":{"date-parts":[[2021,7,6]],"date-time":"2021-07-06T11:06:16Z","timestamp":1625569576000},"page":"2545-2548","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["An unusual case of <scp>anti\u2010D<\/scp> detection in two consecutive D+ patient samples: Antibody carryover on an automated gel platform"],"prefix":"10.1111","volume":"61","author":[{"given":"Kimberly","family":"Gabert","sequence":"first","affiliation":[{"name":"Department of Reference and Transfusion Services IRL, Vitalant  Pittsburgh Pennsylvania USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6850-7495","authenticated-orcid":false,"given":"Jansen N.","family":"Seheult","sequence":"additional","affiliation":[{"name":"Division of Transfusion Medicine, Department of Pathology University of Pittsburgh Medical Center  Pittsburgh Pennsylvania USA"},{"name":"Institution: Vitalant Specialty Laboratories &amp; Therapeutics Vitalant  Pittsburgh Pennsylvania USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael P.","family":"Meyer","sequence":"additional","affiliation":[{"name":"Department Coagulation Laboratory Vitalant Specialty Laboratories &amp; Therapeutics, Vitalant  Pittsburgh Pennsylvania USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Darrell J.","family":"Triulzi","sequence":"additional","affiliation":[{"name":"Division of Transfusion Medicine, Department of Pathology University of Pittsburgh Medical Center  Pittsburgh Pennsylvania USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8746-0549","authenticated-orcid":false,"given":"Alesia","family":"Kaplan","sequence":"additional","affiliation":[{"name":"Division of Transfusion Medicine, Department of Pathology University of Pittsburgh Medical Center  Pittsburgh Pennsylvania USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,7,6]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.4103\/0973-6247.98914"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.21307\/immunohematology-2019-278"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/jalm\/jfz015"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1309\/MMLEYHNBY4WA12J6"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinbiochem.2016.05.020"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cca.2006.04.022"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/jbm.820251107"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ab.2011.02.009"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/0003-2697(83)90738-8"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/jps.2600691031"},{"key":"e_1_2_6_12_1","volume-title":"Title 21 medical devices, subpart J\u2014products used in establishments that manufacture blood and blood products","author":"Code of Federal Regulations","year":"2020"},{"key":"e_1_2_6_13_1","volume-title":"Chemistry and toxicology checklist","author":"College of American Pathologists Commission on Laboratory Accreditation","year":"2017"},{"key":"e_1_2_6_14_1","volume-title":"Statistical quality control for quantitative measurement procedures: principles and definitions; approved guideline. 4th ed. 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