{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T02:08:34Z","timestamp":1789697314003,"version":"4.0.1"},"reference-count":18,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2021,8,19]],"date-time":"2021-08-19T00:00:00Z","timestamp":1629331200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Transfusion"],"published-print":{"date-parts":[[2021,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>All studies of vasovagal syncope (VVS) after blood donation have been performed with civilian donors. We hypothesized that military donors have a lower incidence of VVS and a particular set of predisposing factors.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design and Methods<\/jats:title><jats:p>Retrospective case\u2013control study matching every case of VVS seen from 2011 to 2019 with two controls without VVS from the same blood drive. We used the odds ratio (OR) and its 95% confidence interval (CI), estimated by multivariate logistic regression, to identify independent predictors of VVS.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>There were 105 episodes of VVS among 65.481 whole blood donations (0.15%). VVS was more frequent among donors from military academies than from other military units (0.37% vs. 0.10%, <jats:italic>p<\/jats:italic>\u00a0&lt;\u2009.001) and in collections conducted in mobile inside setups than in mobile buses (0.23% vs. 0.06%, <jats:italic>p<\/jats:italic>\u00a0&lt;\u2009.001). In the multivariate analysis, the only independent predictors of VVS were the status of first\u2010time donor (OR 2.6, 95% CI 1.5\u20134.4; <jats:italic>p<\/jats:italic>\u00a0&lt;\u2009.001) and pre\u2010donation systolic blood pressure (SBP)\u2009&lt;\u2009120\u2009mm\u2009Hg (OR 1.9, 95% CI 1.1\u20133.3; <jats:italic>p<\/jats:italic>\u00a0=\u2009.01). Donors with both risk factors had a 5.5\u2010fold increased risk of VVS than donors without any risk factor. Age and female sex were not predictive of VVS.<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion<\/jats:title><jats:p>Active duty military blood donors have a lower incidence of VVS than that reported in civilian donors. First\u2010time donors and donors with SBP\u2009&lt;\u2009120\u2009mm\u2009Hg should be temporarily deferred when immediate reincorporation to hazardous or strenuous duty tasks after donation is inescapable.<\/jats:p><\/jats:sec>","DOI":"10.1111\/trf.16603","type":"journal-article","created":{"date-parts":[[2021,8,20]],"date-time":"2021-08-20T02:47:53Z","timestamp":1629427673000},"page":"2925-2929","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Vasovagal syncope after blood donation in active duty military personnel of the Spanish Army"],"prefix":"10.1111","volume":"61","author":[{"given":"Nuria","family":"Fraile","sequence":"first","affiliation":[{"name":"Blood Transfusion Center of the Spanish Army  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ester","family":"Fern\u00e1ndez\u2010Cano","sequence":"additional","affiliation":[{"name":"Blood Transfusion Center of the Spanish Army  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ascensi\u00f3n","family":"Ramos","sequence":"additional","affiliation":[{"name":"Blood Transfusion Center of the Spanish Army  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan\u2010Carlos","family":"L\u00f3pez\u2010Aguilar","sequence":"additional","affiliation":[{"name":"Blood Transfusion Center of the Spanish Army  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00eda\u2010Esther","family":"Jim\u00e9nez\u2010Moreno","sequence":"additional","affiliation":[{"name":"Blood Transfusion Center of the Spanish Army  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arturo","family":"Pereira","sequence":"additional","affiliation":[{"name":"Transfusion Service Hospital Cl\u00ednic  Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,8,19]]},"reference":[{"key":"e_1_2_6_2_1","unstructured":"AABB.Donor hemovigilance highlights 2012\u20102017.https:\/\/www.aabb.org\/news-resources\/resources\/hemovigilance\/donor-hemovigilance."},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000056105.87040.2B"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.autneu.2003.10.003"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1537-2995.2009.02397.x"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/tme.12488"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/tme.12275"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.blre.2011.09.003"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/trf.15225"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/trf.15442"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/trf.16333"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/vox.12418"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.2459\/JCM.0000000000001009"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.genm.2012.02.004"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehm208"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1423-0410.2011.01494.x"},{"issue":"1","key":"e_1_2_6_17_1","first-page":"s28","article-title":"Risk factors for complications in donors at first and repeat whole blood donation: a cohort study with assessment of the impact on donor return","volume":"12","author":"Wiersum\u2010Osselton JC","year":"2014","journal-title":"Blood Transfus"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1093\/milmed\/usaa234"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1537-2995.2012.03767.x"}],"container-title":["Transfusion"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/trf.16603","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/trf.16603","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/trf.16603","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,29]],"date-time":"2023-08-29T20:47:51Z","timestamp":1693342071000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/trf.16603"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,8,19]]},"references-count":18,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2021,10]]}},"alternative-id":["10.1111\/trf.16603"],"URL":"https:\/\/doi.org\/10.1111\/trf.16603","archive":["Portico"],"relation":{},"ISSN":["0041-1132","1537-2995"],"issn-type":[{"value":"0041-1132","type":"print"},{"value":"1537-2995","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,8,19]]},"assertion":[{"value":"2021-05-15","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-07-11","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-08-19","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}