{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T11:19:53Z","timestamp":1788347993639,"version":"build-2803163510"},"reference-count":20,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2022,5,2]],"date-time":"2022-05-02T00:00:00Z","timestamp":1651449600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Transfusion"],"published-print":{"date-parts":[[2022,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>To better balance the safety of the blood supply and the inclusion of men who have sex with men (MSM), further improvements are needed to the risk management strategy employed in the Netherlands to reduce transfusion\u2010transmissible infections (TTIs). A gender\u2010neutral individual risk assessment could provide a solution by determining donor eligibility based on sexual behaviors known to increase the risk of TTIs. Our objective is to estimate the proportion of blood donors that would be deferred by such an assessment, as well as their discomfort answering such questions.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study design and methods<\/jats:title><jats:p>Two surveys were distributed in May 2020 to assess sexual behavior in blood donors in the last 4, 6, and 12\u2009months, as well as their discomfort reporting such information. A combination of both surveys measured the extent to which discomfort was associated with reporting sexual behavior. A high\u2010risk sexual behavior pattern was defined as having had multiple sexual partners and having engaged in anal sex, without consistent condom use.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of all 2177 participating whole blood donors, 0.8% report engaging in high\u2010risk sexual behaviors over the last 4\u2009months and would therefore be ineligible to donate. When accounting for the additional proportion of donors that reported such questions would stop them from donating, 2.0% and 3.2% of female and male donors, respectively, would be lost.<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion<\/jats:title><jats:p>Gender\u2010neutral eligibility criteria based on high\u2010risk sexual behaviors may reduce the overall number of eligible donors in the Netherlands, but could make blood donation more accessible to a broader group of donors.<\/jats:p><\/jats:sec>","DOI":"10.1111\/trf.16896","type":"journal-article","created":{"date-parts":[[2022,5,3]],"date-time":"2022-05-03T05:35:52Z","timestamp":1651556152000},"page":"1241-1250","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Balancing non\u2010discriminatory donor selection and blood safety in the Netherlands: Evaluation of an individual risk assessment of sexual behavior"],"prefix":"10.1111","volume":"62","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1675-3608","authenticated-orcid":false,"given":"Brett","family":"Hahn","sequence":"first","affiliation":[{"name":"Athena Institute Vrije Universiteit Amsterdam  Amsterdam the Netherlands"},{"name":"Department of Donor Medicine Research Sanquin Research  Amsterdam the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5733-9254","authenticated-orcid":false,"given":"Franke","family":"Quee","sequence":"additional","affiliation":[{"name":"Department of Donor Medicine Research Sanquin Research  Amsterdam the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7849-0092","authenticated-orcid":false,"given":"Femmeke J.","family":"Prinsze","sequence":"additional","affiliation":[{"name":"Department of Donor Medicine Research Sanquin Research  Amsterdam the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1096-698X","authenticated-orcid":false,"given":"Yves","family":"Gregoire","sequence":"additional","affiliation":[{"name":"H\u00e9ma\u2010Qu\u00e9bec  Quebec City Quebec Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5332-2789","authenticated-orcid":false,"given":"Sheila F.","family":"O'Brien","sequence":"additional","affiliation":[{"name":"Canadian Blood Services  Ottawa Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marc","family":"Germain","sequence":"additional","affiliation":[{"name":"H\u00e9ma\u2010Qu\u00e9bec  Quebec City Quebec Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thijs","family":"van de Laar","sequence":"additional","affiliation":[{"name":"Department of Donor Medicine Research Sanquin Research  Amsterdam the Netherlands"},{"name":"Laboratory of Medical Microbiology OLVG  Amsterdam the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0773-7315","authenticated-orcid":false,"given":"Hans L.","family":"Zaaijer","sequence":"additional","affiliation":[{"name":"Department of Donor Medicine Research Sanquin Research  Amsterdam the Netherlands"},{"name":"Department of Clinical Virology Amsterdam UMC  Amsterdam the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katja","family":"van den Hurk","sequence":"additional","affiliation":[{"name":"Department of Donor Medicine Research Sanquin Research  Amsterdam the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,5,2]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijid.2013.09.016"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1537-2995.2010.02851.x"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tmrv.2007.09.002"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1503\/cmaj.091476"},{"key":"e_1_2_8_6_1","volume-title":"Sanquin annual report 2015","author":"Sanquin Blood Supply Foundation","year":"2016"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1128\/CVI.00053-16"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/vox.12826"},{"issue":"1","key":"e_1_2_8_9_1","first-page":"7","article-title":"Blood donor deferral policies across Europe and characteristics of men who have sex with men screened for human immunodeficiency virus in blood establishments: data from the European men\u2010who\u2010have\u2010sex\u2010with\u2010men internet survey (EMIS)","volume":"16","author":"Schink SB","year":"2018","journal-title":"Blood Transfus"},{"key":"e_1_2_8_10_1","volume-title":"DOMAINE project","author":"Sanquin Blood Supply Foundation","year":"2010"},{"key":"e_1_2_8_11_1","unstructured":"Sanquin editor.Pseudonymized data on age sex Hb levels and deferrals will be extracted from the donor database (eProgesa software application; MAK\u2010SYSTEM) for all new and repeat whole blood donors. Amsterdam the Netherlands;2019."},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciy596"},{"issue":"3","key":"e_1_2_8_13_1","first-page":"441","article-title":"Changing blood donor screening criteria from permanent deferral for men who have sex with men to individual sexual risk assessment: no evidence of a significant impact on the human immunodeficiency virus epidemic in Italy","volume":"11","author":"Suligoi B","year":"2013","journal-title":"Blood Transfus"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/trf.13627"},{"key":"e_1_2_8_15_1","unstructured":"Canadian Blood Services H\u00e9ma\u2010Qu\u00e9bec.Operational impact of alternate risk assessment options;2020(Unpublished report)."},{"key":"e_1_2_8_16_1","unstructured":"Qualtrics.Qualtrics XM. May 2020 ed. 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