{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T22:36:44Z","timestamp":1788907004818,"version":"build-2803163510"},"reference-count":25,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2022,7,15]],"date-time":"2022-07-15T00:00:00Z","timestamp":1657843200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Transfusion"],"published-print":{"date-parts":[[2022,8]]},"abstract":"Abstract<\/jats:title>Background<\/jats:title>At the start of the coronavirus disease 2019 (COVID\u201019) pandemic, widespread blood shortages were anticipated. We sought to determine how hospital blood supply and blood utilization were affected by the first wave of COVID\u201019.<\/jats:p><\/jats:sec>Study Design and Methods<\/jats:title>Weekly red blood cell (RBC) and platelet (PLT) inventory, transfusion, and outdate data were collected from 13 institutions in the United States, Brazil, Canada, and Denmark from March 1st to December 31st of 2020 and 2019. Data from the sites were aligned based on each site's local first peak of COVID\u201019 cases, and data from 2020 (pandemic year) were compared with data from the corresponding period in 2019 (pre\u2010pandemic baseline).<\/jats:p><\/jats:sec>Results<\/jats:title>RBC inventories were 3% lower in 2020 than in 2019 (680 vs. 704, p<\/jats:italic>\u2009<\u2009.001) and 5% fewer RBCs were transfused per week compared to 2019 (477 vs. 501, p<\/jats:italic>\u2009<\u2009.001). However, during the first COVID\u201019 peak, RBC and PLT inventories were higher than normal, as reflected by deviation from par, days on hand, and percent outdated. At this time, 16% fewer inpatient beds were occupied, and 43% fewer surgeries were performed compared to 2019 (p<\/jats:italic>\u2009<\u2009.001). In contrast to 2019 when there was no correlation, there was, in 2020, significant negative correlations between RBC and PLT days on hand and both percentage occupancy of inpatient beds and percentage of surgeries performed.<\/jats:p><\/jats:sec>Conclusion<\/jats:title>During the COVID\u201019 pandemic in 2020, RBC and PLT inventories remained adequate. During the first wave of cases, significant decreases in patient care activities were associated with excess RBC and PLT supplies and increased product outdating.<\/jats:p><\/jats:sec>","DOI":"10.1111\/trf.17023","type":"journal-article","created":{"date-parts":[[2022,7,9]],"date-time":"2022-07-09T08:11:10Z","timestamp":1657354270000},"page":"1559-1570","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Hospital red blood cell and platelet supply and utilization from March to December of the first year of the COVID<\/scp>\u201019 pandemic: The BEST<\/scp> collaborative study"],"prefix":"10.1111","volume":"62","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2292-3167","authenticated-orcid":false,"given":"Wen","family":"Lu","sequence":"first","affiliation":[{"name":"Department of Pathology Brigham and Women's Hospital Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6740-2758","authenticated-orcid":false,"given":"Mark","family":"Yazer","sequence":"additional","affiliation":[{"name":"Department of Pathology University of Pittsburgh Pittsburgh Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4803-0984","authenticated-orcid":false,"given":"Na","family":"Li","sequence":"additional","affiliation":[{"name":"Community Health Sciences Cumming School of Medicine, University of Calgary Calgary Alberta Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1814-9319","authenticated-orcid":false,"given":"Alyssa","family":"Ziman","sequence":"additional","affiliation":[{"name":"Wing\u2010Kwai and Alice Lee\u2010Tsing Chung Transfusion Service, Department of Pathology and Laboratory Medicine David Geffen School of Medicine, University of California Los Angeles Los Angeles California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1941-7733","authenticated-orcid":false,"given":"Silvano","family":"Wendel","sequence":"additional","affiliation":[{"name":"Hospital S\u00edrio\u2010Liban\u00eas Blood Bank S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongying","family":"Tang","sequence":"additional","affiliation":[{"name":"Department of Pathology Brigham and Women's Hospital Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hamilton","family":"Tsang","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine and Pathology, Transfusion Medicine Division University of Washington Seattle Washington USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kjell","family":"Titlestad","sequence":"additional","affiliation":[{"name":"Department of Clinical Immunology Odense University, South Danish Transfusion Services Odense Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9881-703X","authenticated-orcid":false,"given":"Suzanne R.","family":"Thibodeaux","sequence":"additional","affiliation":[{"name":"Department of Pathology and Immunology Washington University School of Medicine St. Louis Missouri USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7107-2595","authenticated-orcid":false,"given":"Andrew W.","family":"Shih","sequence":"additional","affiliation":[{"name":"Department of Pathology and Laboratory Medicine Vancouver General Hospital Vancouver British Columbia Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jessica L.","family":"Poisson","sequence":"additional","affiliation":[{"name":"Department of Pathology Duke University Hospital Durham North Carolina USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5900-0289","authenticated-orcid":false,"given":"Tho","family":"Pham","sequence":"additional","affiliation":[{"name":"Stanford Blood Center Palo Alto California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3614-2353","authenticated-orcid":false,"given":"Suchi","family":"Pandey","sequence":"additional","affiliation":[{"name":"Stanford Blood Center Palo Alto California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5183-6471","authenticated-orcid":false,"given":"Monica B.","family":"Pagano","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine and Pathology, Transfusion Medicine Division University of Washington Seattle Washington USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3764-1787","authenticated-orcid":false,"given":"Hua","family":"Shan","sequence":"additional","affiliation":[{"name":"Transfusion Medicine Service, Department of Pathology Stanford University School of Medicine Stanford California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2375-7503","authenticated-orcid":false,"given":"Mike","family":"Murphy","sequence":"additional","affiliation":[{"name":"Radcliffe Department of Medicine University of Oxford Oxford UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1887-2646","authenticated-orcid":false,"given":"Colin","family":"Murphy","sequence":"additional","affiliation":[{"name":"Department of Pathology University of Maryland School of Medicine Baltimore Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariana Lorenzi","family":"Savioli","sequence":"additional","affiliation":[{"name":"Hemotherapy and Cell Therapy Department Hospital Israelita Albert Einstein S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 Mauro","family":"Kutner","sequence":"additional","affiliation":[{"name":"Hemotherapy and Cell Therapy Department Hospital Israelita Albert Einstein S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2230-8367","authenticated-orcid":false,"given":"Aaron S.","family":"Hess","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology University of Wisconsin\u2010Madison Madison Wisconsin USA"},{"name":"Department of Pathology and Laboratory Medicine University of Wisconsin\u2010Madison Madison Wisconsin USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6731-9516","authenticated-orcid":false,"given":"Magali J.","family":"Fontaine","sequence":"additional","affiliation":[{"name":"Department of Pathology University of Maryland School of Medicine Baltimore Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roberta","family":"Fachini","sequence":"additional","affiliation":[{"name":"Hospital S\u00edrio\u2010Liban\u00eas Blood Bank S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8601-5438","authenticated-orcid":false,"given":"Nancy M.","family":"Dunbar","sequence":"additional","affiliation":[{"name":"Department of Pathology and Laboratory Medicine Dartmouth\u2010Hitchcock Medical Center Lebanon New Hampshire USA"},{"name":"Department of Medicine Dartmouth\u2010Hitchcock Medical Center Lebanon New Hampshire USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0041-804X","authenticated-orcid":false,"given":"Richard M.","family":"Kaufman","sequence":"additional","affiliation":[{"name":"Department of Pathology Brigham and Women's Hospital Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Biomedical Excellence for Safer Transfusions Collaborative","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,7,15]]},"reference":[{"key":"e_1_2_9_2_1","unstructured":"WHO.WHO Director\u2010General's opening remarks at the media briefing on COVID\u201019.2020. Available from:https:\/\/www.who.int\/director\u2010general\/speeches\/detail\/who\u2010director\u2010general\u2010s\u2010opening\u2010remarks\u2010at\u2010the\u2010media\u2010briefing\u2010on\u2010covid\u201019\u2010\u2010\u201011\u2010march\u20102020. Accessed 30 Aug 2021."},{"key":"e_1_2_9_3_1","unstructured":"WHO.World Health Organization: Interim guidance on maintaining a safe and adequate blood supply during the pan\u2010 demic outbreak of coronavirus disease (COVID\u201019).2020. Available from:https:\/\/www.who.int\/publications\/i\/item\/WHO-2019-nCoV-BloodSupply-2021-1. Accessed 30 Aug 2021."},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/trf.15789"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/ajcp\/aqaa111"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/ALN.0000000000003341"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2352-3026(20)30186-1"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.transci.2020.102836"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/vox.13012"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.transci.2020.102982"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/vox.12931"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/vox.13071"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.2450\/2020.0107-20"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/trf.16265"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/trf.16661"},{"key":"e_1_2_9_16_1","unstructured":"American Red Cross.American Red Cross email communication: March 19 2020 from Pampee P. Young M.D. Ph.D. Chief Medical Officer American Red Cross."},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/trf.16051"},{"key":"e_1_2_9_18_1","unstructured":"ACS.COVID\u201019: executive orders by state on dental medical and surgical procedures. Available from:https:\/\/www.facs.org\/covid-19\/legislative-regulatory\/executive-orders. Accessed 22 June 2021."},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/trf.16202"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/trf.15947"},{"issue":"79","key":"e_1_2_9_21_1","first-page":"10","article-title":"Blood transfusion during the COVID\u201019 outbreak","volume":"18","author":"Cai X","year":"2020","journal-title":"Blood Transfus"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tracli.2020.11.002"},{"key":"e_1_2_9_23_1","unstructured":"National Blood Authority.Managing blood and blood product inventory \u2010 tip 3: set appropriate inventory levels. Available from:https:\/\/www.blood.gov.au\/inv-mgt-guideline-tip-3-set-appropriate-levels. Accessed 29 Sept 2021."},{"key":"e_1_2_9_24_1","volume-title":"R: a language and environment for statistical computing","author":"R Core Team","year":"2020"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamahealthforum.2020.0380"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.1111\/trf.16643"}],"container-title":["Transfusion"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/trf.17023","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/trf.17023","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/trf.17023","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,23]],"date-time":"2023-08-23T11:03:21Z","timestamp":1692788601000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/trf.17023"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,7,15]]},"references-count":25,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2022,8]]}},"alternative-id":["10.1111\/trf.17023"],"URL":"https:\/\/doi.org\/10.1111\/trf.17023","archive":["Portico"],"relation":{},"ISSN":["0041-1132","1537-2995"],"issn-type":[{"value":"0041-1132","type":"print"},{"value":"1537-2995","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,7,15]]},"assertion":[{"value":"2022-03-22","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-06-21","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-07-15","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}