{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,27]],"date-time":"2026-03-27T17:51:44Z","timestamp":1774633904416,"version":"3.50.1"},"reference-count":24,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2022,7,25]],"date-time":"2022-07-25T00:00:00Z","timestamp":1658707200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Transfusion"],"published-print":{"date-parts":[[2022,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Multiple reports suggest that cold\u2010stored low\u2010titer type O whole blood (LTOWB) is becoming a preferred transfusion product for resuscitating massive hemorrhage across trauma, obstetrical, and pediatric services. However, we know of no reports of using this product for emergency transfusion of newborn infants after acute severe hemorrhage.<\/jats:p><\/jats:sec><jats:sec><jats:title>Case Report<\/jats:title><jats:p>We report our experience with emergency transfusion of re\u2010warmed LTOWB using a fluid warmer for the resuscitation of a hypotensive 25\u2010week gestation neonate following acute and severe placental abruption. The transfusion was tolerated well, without evidence of hemolysis or other complications.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>This is the first report of which we are aware of transfusing warmed LTOWB to a preterm neonate. Our positive experience leads us to speculate that this product could have a role for neonates following acute severe blood loss.<\/jats:p><\/jats:sec>","DOI":"10.1111\/trf.17034","type":"journal-article","created":{"date-parts":[[2022,7,25]],"date-time":"2022-07-25T07:04:13Z","timestamp":1658732653000},"page":"1923-1926","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["First report of transfusing low\u2010titer cold\u2010stored type O whole blood to an extremely\u2010low\u2010birth\u2010weight neonate after acute blood loss"],"prefix":"10.1111","volume":"62","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2488-2568","authenticated-orcid":false,"given":"Nicholas R.","family":"Carr","sequence":"first","affiliation":[{"name":"Division of Neonatology, Department of Pediatrics University of Utah Health  Salt Lake City Utah USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5228-6501","authenticated-orcid":false,"given":"Whitley L.","family":"Hulse","sequence":"additional","affiliation":[{"name":"Division of Neonatology, Department of Pediatrics University of Utah Health  Salt Lake City Utah USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7946-0290","authenticated-orcid":false,"given":"Timothy M.","family":"Bahr","sequence":"additional","affiliation":[{"name":"Division of Neonatology, Department of Pediatrics University of Utah Health  Salt Lake City Utah USA"},{"name":"Obstetric and Neonatal Operations, Department of Neonatology Intermountain Healthcare  Murray Utah USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jessica M.","family":"Davidson","sequence":"additional","affiliation":[{"name":"Division of Neonatology, Department of Pediatrics University of Utah Health  Salt Lake City Utah USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sarah J.","family":"Ilstrup","sequence":"additional","affiliation":[{"name":"Department of Pathology Intermountain Medical Center Intermountain Healthcare Transfusion Medicine Service  Murray Utah USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert D.","family":"Christensen","sequence":"additional","affiliation":[{"name":"Division of Neonatology, Department of Pediatrics University of Utah Health  Salt Lake City Utah USA"},{"name":"Obstetric and Neonatal Operations, Department of Neonatology Intermountain Healthcare  Murray Utah USA"},{"name":"Center for Iron and Heme Disorders University of Utah Health  Salt Lake City Utah 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