{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T09:09:35Z","timestamp":1790672975393,"version":"4.1.0"},"reference-count":21,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2022,8,2]],"date-time":"2022-08-02T00:00:00Z","timestamp":1659398400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003246","name":"Nederlandse Organisatie voor Wetenschappelijk Onderzoek","doi-asserted-by":"publisher","award":["VIDI grant\/09150172010047"],"award-info":[{"award-number":["VIDI grant\/09150172010047"]}],"id":[{"id":"10.13039\/501100003246","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Transfusion"],"published-print":{"date-parts":[[2022,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Transfusion\u2010related acute lung injury (TRALI) is a severe complication of plasma transfusion, though the use of solvent\/detergent pooled plasma (SDP) has nearly eliminated reported TRALI cases. The goal of this study was to investigate the incidence of TRALI in intensive care units (ICU) following the replacement of quarantined fresh frozen plasma (qFFP) by SDP.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Study design and methods<\/jats:title>\n                    <jats:p>A retrospective multicenter observational before\u2013after cohort study was performed during two 6\u2010month periods, before (April\u2013October 2014) and after the introduction of SDP (April\u2013October 2015), accounting for a washout period. A full chart review was performed for patients who received \u22651 plasma units and developed hypoxemia within 24\u2009h.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      During the study period, 8944 patients were admitted to the ICU. Exactly 1171 quarantine fresh frozen plasma (qFFP) units were transfused in 376 patients, and respectively, 2008 SDP units to 396 patients after implementation. Ten TRALI cases occurred during the qFFP and nine cases occurred during the SDP period, in which plasma was transfused. The incidence was 0.85% (CI95%: 0.33%\u20131.4%) per unit qFFP and 0.45% (CI95%: 0.21%\u20130.79%,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.221) per SDP unit. One instance of TRALI occurred after a single SDP unit. Mortality was 70% for patients developing TRALI in the ICU compared with 22% in patients receiving at least one plasma transfusion.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Implementation of SDP lowered the incidence of TRALI in which plasma products were implicated, though not significantly. Clinically diagnosed TRALI can still occur following SDP transfusion. Developing TRALI in the ICU was associated with high mortality rates, therefore, clinicians should remain vigilant.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/trf.17049","type":"journal-article","created":{"date-parts":[[2022,8,3]],"date-time":"2022-08-03T02:48:23Z","timestamp":1659494903000},"page":"1752-1762","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Incidence of transfusion\u2010related acute lung injury temporally associated with solvent\/detergent plasma use in the ICU: A retrospective before and after implementation study"],"prefix":"10.1111","volume":"62","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5820-4530","authenticated-orcid":false,"given":"Robert B.","family":"Klanderman","sequence":"first","affiliation":[{"name":"Department of Intensive Care Amsterdam University Medical Centers \u2013 AMC  Amsterdam The Netherlands"},{"name":"Laboratory of Experimental Intensive Care and Anesthesiology Amsterdam University Medical Centers \u2013 AMC  Amsterdam The Netherlands"},{"name":"Department of Anesthesiology Amsterdam University Medical Centers \u2013 AMC  Amsterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Niels","family":"van Mourik","sequence":"additional","affiliation":[{"name":"Department of Intensive Care Amsterdam University Medical Centers \u2013 AMC  Amsterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dorus","family":"Eggermont","sequence":"additional","affiliation":[{"name":"Department of Intensive Care Amsterdam University Medical Centers \u2013 AMC  Amsterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna\u2010Linda","family":"Peters","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology University Medical Center Utrecht  Utrecht The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pieter R.","family":"Tuinman","sequence":"additional","affiliation":[{"name":"Department of Intensive Care Amsterdam University Medical Centers \u2013 VUmc  Amsterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rob","family":"Bosman","sequence":"additional","affiliation":[{"name":"Department of Intensive Care Onze Lieve Vrouwe Gasthuis \u2013 Locatie Oost  Amsterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Henrik","family":"Endeman","sequence":"additional","affiliation":[{"name":"Department of Intensive Care Onze Lieve Vrouwe Gasthuis \u2013 Locatie Oost  Amsterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olaf L.","family":"Cremer","sequence":"additional","affiliation":[{"name":"Department of Intensive Care University Medical Center Utrecht  Utrecht The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sesmu M.","family":"Arbous","sequence":"additional","affiliation":[{"name":"Department of Intensive Care Leiden University Medical Center  Leiden The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3453-7186","authenticated-orcid":false,"given":"Alexander P. J.","family":"Vlaar","sequence":"additional","affiliation":[{"name":"Department of Intensive Care Amsterdam University Medical Centers \u2013 AMC  Amsterdam The Netherlands"},{"name":"Laboratory of Experimental Intensive Care and Anesthesiology Amsterdam University Medical Centers \u2013 AMC  Amsterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,8,2]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.CCM.0000214292.62276.8E"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(12)62197-7"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.CCM.0000104112.34142.79"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1537-2995.2010.02652.x"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0000000000000675"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1537-2995.2006.00930.x"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.200702-271OC"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.transci.2010.09.004"},{"key":"e_1_2_10_10_1","first-page":"277","article-title":"Is solvent\/detergent plasma better than standard fresh\u2010frozen plasma? A systematic review and an expert consensus document","volume":"14","author":"Marietta M","year":"2016","journal-title":"Blood Transfus"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/trf.14245"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1537-2995.2005.00587.x"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1159\/000323552"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.3324\/haematol.2019.222083"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/trf.15311"},{"key":"e_1_2_10_16_1","article-title":"Proposed standard definitions for surveillance of non infectious adverse transfusion reactions","author":"Working Party on Haemovigilance","year":"2013","journal-title":"Int Soc Blood Transfus"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/trf.12816"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0b013e3181cc4d4b"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2010-10-313973"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1537-2995.1985.25686071434.x"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1537-2995.2009.02345.x"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1213\/ANE.0000000000001730"}],"container-title":["Transfusion"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/trf.17049","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/trf.17049","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/trf.17049","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,21]],"date-time":"2023-08-21T18:11:23Z","timestamp":1692641483000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/trf.17049"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,8,2]]},"references-count":21,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2022,9]]}},"alternative-id":["10.1111\/trf.17049"],"URL":"https:\/\/doi.org\/10.1111\/trf.17049","archive":["Portico"],"relation":{},"ISSN":["0041-1132","1537-2995"],"issn-type":[{"value":"0041-1132","type":"print"},{"value":"1537-2995","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,8,2]]},"assertion":[{"value":"2021-12-15","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-06-11","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-08-02","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}