{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,10]],"date-time":"2026-04-10T04:23:17Z","timestamp":1775794997215,"version":"3.50.1"},"reference-count":26,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2022,12,24]],"date-time":"2022-12-24T00:00:00Z","timestamp":1671840000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Transfusion"],"published-print":{"date-parts":[[2023,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Previous studies have demonstrated low first\u2010time donor return rates (DRR) following catastrophic events. Little is known, however, about the influence of demographic factors on the DRR of first\u2010time donors during the COVID\u201019 pandemic, including the unique motivation of COVID\u201019 convalescent plasma (CCP) donors as compared to non\u2010CCP donors.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design and Methods<\/jats:title><jats:p>Thirteen blood collection organizations submitted deidentified data from first\u2010time CCP and non\u2010CCP donors returning for regular (non\u2010CCP) donations during the pandemic. DRR was calculated as frequencies. Demographic factors associated with returning donors: race\/ethnicity, gender, and generation (Gen Z: 19\u201324, Millennial: 25\u201340, Gen X: 41\u201356, and Boomer: \u226557\u2009years old), within the CCP and non\u2010CCP first\u2010time cohorts were compared using chi\u2010square test at <jats:italic>p<\/jats:italic>\u2009&lt;\u2009.05 statistical significance.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>From March 2020 through December 2021, there were a total of 44,274 first\u2010time CCP and 980,201 first\u2010time non\u2010CCP donors. DRR were 14.6% (range 11.9%\u201343.3%) and 46.6% (range 10.0%\u201376.9%) for CCP and non\u2010CCP cohorts, respectively. Age over 40\u2009years (Gen X and Boomers), female gender, and White race were each associated with higher return in both donor cohorts (<jats:italic>p<\/jats:italic>\u2009&lt;\u2009.001). For the non\u2010CCP return donor cohort, the Millennial and Boomers were comparable.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The findings demonstrate differences in returning donor trends between the two donor cohorts. The motivation of a first\u2010time CCP donor may be different than that of a non\u2010CCP donor. Further study to improve first\u2010time donor engagement would be worthwhile to expand the donor base with a focus on blood donor diversity emphasizing engagement of underrepresented minorities and younger donors.<\/jats:p><\/jats:sec>","DOI":"10.1111\/trf.17229","type":"journal-article","created":{"date-parts":[[2022,12,23]],"date-time":"2022-12-23T05:15:59Z","timestamp":1671772559000},"page":"552-563","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Demographics of first\u2010time donors returning for donation during the pandemic: <scp>COVID<\/scp>\u201019 convalescent plasma versus standard blood product donors"],"prefix":"10.1111","volume":"63","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1309-9770","authenticated-orcid":false,"given":"Nancy L.","family":"Van Buren","sequence":"first","affiliation":[{"name":"Division of New York Blood Center Innovative Blood Resources  Saint Paul Minnesota 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