{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,17]],"date-time":"2026-04-17T03:04:12Z","timestamp":1776395052051,"version":"3.51.2"},"reference-count":35,"publisher":"Wiley","issue":"S3","license":[{"start":{"date-parts":[[2023,4,18]],"date-time":"2023-04-18T00:00:00Z","timestamp":1681776000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Transfusion"],"published-print":{"date-parts":[[2023,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>RhD\u2010negative blood products are in chronic short supply leading to renewed interest in utilizing RhD\u2010positive blood products for emergency transfusions. This study assessed parental perceptions of emergency RhD\u2010positive blood use in children.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A survey of parents\/guardians was conducted on their tolerance of transfusing RhD\u2010positive blood to RhD\u2010negative female children \u226417\u2009years old at four level 1 pediatric hospitals.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In total, 621 parents\/guardians were approached of whom 378\/621 (61%) completed the survey in its entirety and were included in the analysis. Respondents were mostly females [295\/378 (78%)], White [242\/378 (64%)], had some college education [217\/378 (57%)] and less than $60,000 annual income [193\/378 (51%)]. Respondents had a total of 547 female children. Most children's ABO [320\/547 (59%)] and RhD type [348\/547 (64%)] were not known by their parents; of children with known RhD type, 58\/186 (31%) were RhD\u2010negative. When the risk of harm to a future fetus was given as 0\u20136%, more than 80% of respondents indicated that they were likely to accept RhD\u2010positive blood transfusions on behalf of RhD\u2010negative female children in a life\u2010threatening situation. The rate of willingness to accept emergent RhD\u2010incompatible blood transfusions significantly increased as the potential survival benefit of the transfusion increased.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Most parents were willing to accept RhD\u2010positive blood products on behalf of RhD\u2010negative female children in an emergency situation. Further discussions and evidence\u2010based guidelines on transfusing RhD\u2010positive blood products to RhD\u2010unknown females in emergency settings are needed.<\/jats:p><\/jats:sec>","DOI":"10.1111\/trf.17334","type":"journal-article","created":{"date-parts":[[2023,3,27]],"date-time":"2023-03-27T09:13:35Z","timestamp":1679908415000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Parent perceptions of emergent blood transfusion in children"],"prefix":"10.1111","volume":"63","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0307-0472","authenticated-orcid":false,"given":"Katrina M.","family":"Morgan","sequence":"first","affiliation":[{"name":"Department of General Surgery University of Pittsburgh Medical Center  Pittsburgh Pennsylvania USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rachel","family":"Lobo","sequence":"additional","affiliation":[{"name":"University of Pittsburgh  Pittsburgh 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