{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,24]],"date-time":"2026-08-24T14:32:04Z","timestamp":1787581924524,"version":"build-2736575974"},"reference-count":22,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2023,7,17]],"date-time":"2023-07-17T00:00:00Z","timestamp":1689552000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Transfusion"],"published-print":{"date-parts":[[2023,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Our previous showed that a blood management program in the cardiopulmonary bypass (CPB) department, reduced red blood cell (RBC) transfusion and complications, but assessing transfusion practice solely based on transfusion rates was insufficient. This study aimed to design a risk stratification score to predict perioperative RBC transfusion to guide targeted measures for on\u2010pump cardiac surgery patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design and Methods<\/jats:title><jats:p>We analyzed data from 42,435 adult cardiac patients. Eight predictors were entered into the final model including age, sex, anemia, New York Heart Association classification, body surface area, cardiac surgery history, emergency surgery, and surgery type. We then simplified the score to an integer\u2010based system. The area under the receiver operating characteristic curve (AUC), Hosmer\u2013Lemeshow goodness\u2010of\u2010fit test, and a calibration curve were used for its performance test. The score was compared to existing scores.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The final score included eight predictors. The AUC for the model was 0.77 (95% CI, 0.76\u20130.77) and 0.77 (95% CI, 0.76\u20130.78) in the training and test set, respectively. The calibration curves showed a good fit. The risk score was finally grouped into low\u2010risk (score of 0\u201313 points), medium\u2010risk (14\u201319 points), and high\u2010risk (more than 19 points). The score had better predictive power compared to the other two existing risk scores.<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion<\/jats:title><jats:p>We developed an effective risk stratification score with eight variables to predict perioperative RBC transfusion for on\u2010pump cardiac surgery. It assists perfusionists in proactively preparing blood conservation measures for high\u2010risk patients before surgery.<\/jats:p><\/jats:sec>","DOI":"10.1111\/trf.17487","type":"journal-article","created":{"date-parts":[[2023,7,17]],"date-time":"2023-07-17T12:28:30Z","timestamp":1689596910000},"page":"1495-1505","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["A transfusion risk stratification score to facilitate quality management in cardiopulmonary bypass"],"prefix":"10.1111","volume":"63","author":[{"given":"Qiaoni","family":"Zhang","sequence":"first","affiliation":[{"name":"Department of Cardiopulmonary Bypass Fuwai Hospital, Chinese Academy of Medical Science and Peking Union Medical College, National Clinical Research Center for Cardiovascular Disease  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuchen","family":"Gao","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology Fuwai Hospital, Chinese Academy of Medical Science and Peking Union Medical College, National Clinical Research Center for Cardiovascular Disease  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"Tian","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology Beijing Anzhen Hospital, Capital Medical University  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sizhe","family":"Gao","sequence":"additional","affiliation":[{"name":"Department of Cardiopulmonary Bypass Fuwai Hospital, Chinese Academy of Medical Science and Peking Union Medical College, National Clinical Research Center for Cardiovascular Disease  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaolin","family":"Diao","sequence":"additional","affiliation":[{"name":"Department of Information Center Fuwai Hospital, Chinese Academy of Medical Science and Peking Union Medical College, National Clinical Research Center for Cardiovascular Disease  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongwen","family":"Ji","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology Fuwai Hospital, Chinese Academy of Medical Science and Peking Union Medical College, National Clinical Research Center for Cardiovascular Disease  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuefu","family":"Wang","sequence":"additional","affiliation":[{"name":"Surgery Intensive Care Unit &amp; 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