{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,7]],"date-time":"2026-09-07T11:12:11Z","timestamp":1788779531639,"version":"build-2803163510"},"reference-count":22,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2024,2,21]],"date-time":"2024-02-21T00:00:00Z","timestamp":1708473600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Transfusion"],"published-print":{"date-parts":[[2024,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Sanquin donor medicine department is informed when donations or their components are rejected. This can occur isolated or frequently. It is undesirable because the donations cannot be used and there may be an underlying medical cause. Based on regional approaches, a uniform procedure was developed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Information about whole blood, plasma\u2010 plateletpheresis donations from which one or more components were rejected for filtration time (&gt;2\u2009h), hemolysis or clots were extracted from blood bank information system. After rejection of two successive components or donations or total \u22653 the donor is contacted. Depending on the medical history and investigation by the family doctor, the donor carrier is re\u2010evaluated. We looked for the causes of the discarded products and performed a survey among blood services regarding polices with discarded products.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>One or more components from 1742 of about 2.2 million successful donations (0.08%) were rejected. The highest percentage of rejection was seen in plateletpheresis (1.5%), all for clots. No underlying medical causes were found. 24 whole blood donors were found to have sickle cell trait (SCT) and were permanently deferred.<\/jats:p><jats:p>The policies for follow\u2010up after discarded products or acceptance of SCT donors vary between the 16 blood banks. Six organizations do not follow\u2010up donors and seven accept SCT for blood or plasma donation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Informing donors with repeated discarded products avoids the non\u2010use of donations. Causes of repeated discarded products can be found by follow\u2010up of donors. The results of the survey indicate a large discrepancy in policies applied worldwide.<\/jats:p><\/jats:sec>","DOI":"10.1111\/trf.17763","type":"journal-article","created":{"date-parts":[[2024,2,21]],"date-time":"2024-02-21T13:09:13Z","timestamp":1708520953000},"page":"572-577","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Donors with repeated blood product discards for filtration problems, clots or hemolysis: Causes and follow\u2010up"],"prefix":"10.1111","volume":"64","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1791-6421","authenticated-orcid":false,"given":"Niubel","family":"D\u00edaz Padilla","sequence":"first","affiliation":[{"name":"Donor Medicine Department Sanquin Blood Supply Foundation  Amsterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3451-9911","authenticated-orcid":false,"given":"Johanna C","family":"Wiersum\u2010Osselton","sequence":"additional","affiliation":[{"name":"Donor Medicine Department Sanquin Blood Supply Foundation  Amsterdam The Netherlands"},{"name":"TRIP, National Hemovigilance &amp; Biovigilance Office  Leiden The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shahryar","family":"Ghasemi Nezjad","sequence":"additional","affiliation":[{"name":"Donor Medicine Department Sanquin Blood Supply Foundation  Amsterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gitta","family":"Dijkshoorn","sequence":"additional","affiliation":[{"name":"Donor Medicine Department Sanquin Blood Supply Foundation  Amsterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fernando","family":"Gonzalez\u2010Garcia","sequence":"additional","affiliation":[{"name":"Donor Medicine Department Sanquin Blood Supply Foundation  Amsterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3591-5513","authenticated-orcid":false,"given":"V\u0115ra M. J.","family":"Novotny","sequence":"additional","affiliation":[{"name":"Department of Medical Affairs Sanquin Blood Supply Foundation  Amsterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,2,21]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0887-7963(00)80114-5"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01696350"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1537-2995.2007.01281.x"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/trf.17021"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.transci.2021.103146"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tmrv.2004.03.002"},{"issue":"3","key":"e_1_2_9_8_1","first-page":"16","article-title":"Red blood cell filtration failure rates vary by collection methods and devices","volume":"59","author":"Townsend M","year":"2019","journal-title":"Transfusion"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.4103\/0973-6247.95045"},{"key":"e_1_2_9_10_1","volume-title":"Leucodepletion Failures","author":"Clarkson J","year":"2013"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-0502(01)00054-4"},{"issue":"10","key":"e_1_2_9_12_1","first-page":"55S","article-title":"Residual WBCs in leukocytereduction filtered hemoglobin S positive RBCs","volume":"40","author":"Harbin K","year":"2000","journal-title":"Transfusion"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1537-2995.2007.01452.x"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1537-2995.2001.41101192.x"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3148.2006.00661.x"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1423-0410.1997.73100543.x"},{"key":"e_1_2_9_17_1","unstructured":"Guide to the preparation use and quality assurance of lood components.European Committee (Partial Agreement) on Blood Transfusion (CD\u2010P\u2010TS) EDQM 21st Edition 2023 Chapter 4 page 190.https:\/\/www.edqm.eu\/en\/blood-guide"},{"key":"e_1_2_9_18_1","unstructured":"WHO Blood Donor selection guidelines (Section 5.1.2. Chapter 5 page 50).https:\/\/www.who.int\/publications\/i\/item\/9789241548519"},{"key":"e_1_2_9_19_1","volume-title":"Standards for blood banks and transfusion services (ed 32)","author":"ABBB AABB","year":"2020"},{"key":"e_1_2_9_20_1","unstructured":"Guidance for Industry Pre\u2010Storage Leukocyte Reduction of Whole Blood and Blood Components Intended for Transfusion.2012https:\/\/www.hhs.gov\/guidance\/document\/pre\u2010storage\u2010leukocyte\u2010reduction\u2010whole\u2010blood\u2010and\u2010blood\u2010components\u2010intended\u2010transfusionAccessed 16 Oct. 2022."},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12878-018-0128-x"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1093\/labmed\/lmac061"},{"key":"e_1_2_9_23_1","first-page":"1","article-title":"A new insight into apheresis platelet donation by sickle cell trait carriers: evidences of safety and quality","volume":"4","author":"Barbosa SAT","year":"2019","journal-title":"Hematol Med Oncol"}],"container-title":["Transfusion"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/trf.17763","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,4,9]],"date-time":"2024-04-09T19:00:08Z","timestamp":1712689208000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/trf.17763"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,2,21]]},"references-count":22,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2024,4]]}},"alternative-id":["10.1111\/trf.17763"],"URL":"https:\/\/doi.org\/10.1111\/trf.17763","archive":["Portico"],"relation":{},"ISSN":["0041-1132","1537-2995"],"issn-type":[{"value":"0041-1132","type":"print"},{"value":"1537-2995","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,2,21]]},"assertion":[{"value":"2023-07-04","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-01-30","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-02-21","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}