{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,3]],"date-time":"2025-12-03T20:40:09Z","timestamp":1764794409376,"version":"3.40.5"},"reference-count":38,"publisher":"Wiley","issue":"S2","license":[{"start":{"date-parts":[[2024,4,2]],"date-time":"2024-04-02T00:00:00Z","timestamp":1712016000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Transfusion"],"published-print":{"date-parts":[[2024,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>The VCM is a point\u2010of\u2010care analyzer using a new viscoelastometry technique for rapid assessment of hemostasis on fresh whole blood. Its characteristics would make it suitable for use in austere environments. The purpose of this study was to evaluate the VCM in terms of repeatability, reproducibility and interanalyzer correlation, reference values in our population, correlation with standard coagulation assays and platelet count, correlation with the TEG5000 analyzer and resistance to stress conditions mimicking an austere environment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Repeatability, reproducibility, and interanalyzer correlation were performed on quality control samples (<jats:italic>n<\/jats:italic>\u2009=\u200910). Reference values were determined from blood donor samples (<jats:italic>n<\/jats:italic>\u2009=\u200960). Correlations with standard biological assays were assessed from ICU patients (<jats:italic>n<\/jats:italic>\u2009=\u200930) and blood donors (<jats:italic>n<\/jats:italic>\u2009=\u200960) samples. Correlation with the TEG5000 was assessed from blood donor samples. Evaluation of vibration resistance was performed on blood donor (<jats:italic>n<\/jats:italic>\u2009=\u20095) and quality control (<jats:italic>n<\/jats:italic>\u2009=\u20095) samples.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The CVs for repeatability and reproducibility ranged from 0% to 11%. Interanalyzer correlation found correlation coefficients (<jats:italic>r<\/jats:italic><jats:sup>2<\/jats:sup>) ranging from 0.927 to 0.997. Our reference values were consistent with those provided by the manufacturer. No robust correlation was found with conventional coagulation tests. The correlation with the TEG5000 was excellent with <jats:italic>r<\/jats:italic><jats:sup>2<\/jats:sup> ranging from 0.75 to 0.92. Resistance to stress conditions was excellent.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The VCM analyzer is a reliable, easy\u2010to\u2010use instrument that correlates well with the TEG5000. Despite some logistical constraints, the results suggest that it can be used in austere environments. Further studies are required before its implementation.<\/jats:p><\/jats:sec>","DOI":"10.1111\/trf.17808","type":"journal-article","created":{"date-parts":[[2024,4,3]],"date-time":"2024-04-03T06:23:55Z","timestamp":1712125435000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["In vitro evaluation of a new viscoelastometry\u2010based point\u2010of\u2010care analyzer"],"prefix":"10.1111","volume":"64","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9602-1329","authenticated-orcid":false,"given":"Vanina","family":"Corominas","sequence":"first","affiliation":[{"name":"French Military Blood Institute  Clamart France"},{"name":"French Military Health Service Academy Ecole du Val\u2010de\u2010Gr\u00e2ce  Paris France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Chiniard","sequence":"additional","affiliation":[{"name":"French Military Health Service Academy Ecole du 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