{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T09:25:36Z","timestamp":1773048336314,"version":"3.50.1"},"reference-count":21,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2024,12,17]],"date-time":"2024-12-17T00:00:00Z","timestamp":1734393600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Transfusion"],"published-print":{"date-parts":[[2025,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>We reviewed trauma blood use at our US regional trauma center 2011\u20132022\u2014including PROPPR trial participation 2012\u20132014 and initiation of whole blood availability in 2019\u2014to assess the implementation of early coagulation support in acute trauma care.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design\/Methods<\/jats:title><jats:p>We identified all acute trauma patients recorded by our Trauma Registry as arriving at our large US regional Level 1 trauma center from April 6, 2011 (Blood Bank opening) through December 2022. Patient cohort data were then linked directly to Blood Bank final\u2010product\u2010issue date\/time data to identify patients receiving any blood product in the first 24\u2009h of care and then, specifically, at least one unit of Red Blood Cells (RBC), Plasma, or Whole Blood (WB). Results were binned as: \u201cRBC first,\u201d \u201cPlasma first,\u201d \u201cBoth at the same time,\u201d or \u201cWB first.\u201d<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Over the study period, 73,634 acute trauma patients received care, and 12,927 received at least one unit of a blood product. The proportion receiving plasma or a combination of plasma and RBCs as the initial transfusion increased after 2015 from 33% to 66%, while the proportion receiving packed RBCs alone decreased from 57% to about 18%. Since its introduction in 2019, the use of WB as the first product has grown to 20%.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>This retrospective cohort study documents the increasing use of plasma and now WB as initial products issued in trauma resuscitation, reflecting acceptance of coagulation support as the standard of care and the use of hemostatic resuscitation protocols.<\/jats:p><\/jats:sec>","DOI":"10.1111\/trf.18100","type":"journal-article","created":{"date-parts":[[2024,12,17]],"date-time":"2024-12-17T13:13:49Z","timestamp":1734441229000},"page":"255-259","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Evolving patterns of first blood product use in trauma in the era of hemorrhage control resuscitation"],"prefix":"10.1111","volume":"65","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2097-3200","authenticated-orcid":false,"given":"Maryam","family":"Asif","sequence":"first","affiliation":[{"name":"Department of Laboratory Medicine and Pathology University of Washington  Seattle Washington USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7388-5362","authenticated-orcid":false,"given":"Safee U.","family":"Haider","sequence":"additional","affiliation":[{"name":"Shaikh Khalifa bin Zayed al Nahyan Medical and Dental College, Shaikh Zayed Medical Complex  Lahore Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhinan","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine and Pathology University of Washington  Seattle Washington USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6832-881X","authenticated-orcid":false,"given":"Lynn G.","family":"Stansbury","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine and Pathology University of Washington  Seattle Washington USA"},{"name":"Department of Anesthesiology and Pain Medicine University of Washington  Seattle Washington USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8596-4420","authenticated-orcid":false,"given":"John R.","family":"Hess","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine and Pathology University of Washington  Seattle Washington USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,12,17]]},"reference":[{"key":"e_1_2_9_2_1","unstructured":"National Trauma Institute.Trauma Statistics and Facts.2015Retrieved fromhttps:\/\/www.nattrauma.org\/trauma-statistics-facts\/. 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