{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T12:31:18Z","timestamp":1790425878222,"version":"4.1.0"},"reference-count":24,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2025,2,24]],"date-time":"2025-02-24T00:00:00Z","timestamp":1740355200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"publisher","award":["75N92019D00038"],"award-info":[{"award-number":["75N92019D00038"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Transfusion"],"published-print":{"date-parts":[[2025,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>In many countries, including Brazil, time\u2010based blood donation deferral policies for gay, bisexual, and other men who have sex with men (gbMSM) have been replaced by individual donor assessment (IDA). We examined HIV prevalence and incidence among first\u2010time (FTD) and repeat donors (RD), comparing data from ~3.5\u2009years before and after the IDA policy implementation in 2020.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design and Methods<\/jats:title><jats:p>The Recipient Epidemiology and Donor Evaluation Study\u2010IV\u2010Pediatric (REDS\u2010IV\u2010P) Brazil component collects blood donor screening data from five public centers. From January 2017 to December 2023, we report frequencies, rates, and 95% confidence interval (CI) of confirmed HIV\u2010positive donations among FTD, HIV NAT\u2010yield rates for FTD and RD, and the incidence of confirmed HIV among RD before and after the policy change. We also report multivariable regression analysis results.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Confirmed HIV prevalence in FTD was 79 per 100,000 (95% CI 72\u201387) before and 100 per 100,000 (95% CI 90\u2013109) after the policy change, with differences between centers. HIV NAT\u2010yield rates decreased for RD (<jats:italic>p<\/jats:italic>\u2009=\u2009.0025), with no change for FTD (<jats:italic>p<\/jats:italic>\u2009=\u2009.3). HIV incidence in RD did not increase (12.4 [95% CI: 11.1\u201313.9] vs. 10.3 [95% CI: 9\u201311.7] per 100,000 person\u2010years).<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion<\/jats:title><jats:p>Our findings showed no significant difference in HIV incidence among RD. Although HIV prevalence among FTD increased, there was no rise in HIV NAT\u2010yield donations. The analysis highlights challenges in interpreting changes within specific groups and blood centers, underscoring the importance of multicenter monitoring of transfusion\u2010transmitted infections.<\/jats:p><\/jats:sec>","DOI":"10.1111\/trf.18168","type":"journal-article","created":{"date-parts":[[2025,3,11]],"date-time":"2025-03-11T22:43:07Z","timestamp":1741732987000},"page":"685-695","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Assessing <scp>HIV<\/scp> trends among blood donors in five Brazilian blood centers: The impact of individual donor assessment"],"prefix":"10.1111","volume":"65","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3217-5898","authenticated-orcid":false,"given":"Renata","family":"Buccheri","sequence":"first","affiliation":[{"name":"Vitalant Research Institute  San Francisco California USA"},{"name":"University of California San Francisco  San Francisco California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-7844-7821","authenticated-orcid":false,"given":"Donald E.","family":"Warden","sequence":"additional","affiliation":[{"name":"Westat  Rockville Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcio","family":"Oikawa","sequence":"additional","affiliation":[{"name":"Universidade Municipal de Sao Caetano do Sul  Sao Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7046-7245","authenticated-orcid":false,"given":"Eduard","family":"Grebe","sequence":"additional","affiliation":[{"name":"Vitalant Research Institute  San Francisco California USA"},{"name":"University of California San Francisco  San Francisco California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carolina","family":"Miranda","sequence":"additional","affiliation":[{"name":"Funda\u00e7\u00e3o Hemominas  Belo Horizonte Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luiz","family":"Amorim","sequence":"additional","affiliation":[{"name":"Funda\u00e7\u00e3o Hemorio  Rio de Janeiro Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paula","family":"Loureiro","sequence":"additional","affiliation":[{"name":"Funda\u00e7\u00e3o Hemope  Recife Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maisa","family":"Ribeiro","sequence":"additional","affiliation":[{"name":"Funda\u00e7\u00e3o Hemominas  Belo Horizonte Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nelson","family":"Fraji","sequence":"additional","affiliation":[{"name":"Funda\u00e7\u00e3o Hemoam  Manaus Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cesar","family":"de Almeida\u2010Neto","sequence":"additional","affiliation":[{"name":"Funda\u00e7\u00e3o Pro\u2010Sangue Hemocentro de Sao Paulo  Sao Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2623-5126","authenticated-orcid":false,"given":"Ester","family":"Sabino","sequence":"additional","affiliation":[{"name":"Universidade Municipal de Sao Caetano do Sul  Sao Paulo Brazil"},{"name":"Universidade de Sao Paulo  Sao Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6251-366X","authenticated-orcid":false,"given":"Brian","family":"Custer","sequence":"additional","affiliation":[{"name":"Vitalant Research Institute  San Francisco California USA"},{"name":"University of California San Francisco  San Francisco California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,2,24]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.htct.2018.09.002"},{"key":"e_1_2_9_3_1","unstructured":"Ag\u00eancia Nacional de Vigil\u00e2ncia Sanit\u00e1ria \u2013 Anvisa.Guia para inclus\u00e3o de crit\u00e9rios na triagem cl\u00ednica e epidemiol\u00f3gica de candidatos a doa\u00e7\u00e3o de sangue baseados em pr\u00e1ticas individuais acrescidas de risco para infec\u00e7\u00f5es transmiss\u00edveis pelo sangue. Report No.: Guia no. 34\/2020 \u2013 vers\u00e3o 1.2020."},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/tme.12225"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/trf.17515"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/trf.17164"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1537-2995.2010.02773.x"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/trf.13939"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.2020007003"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/trf.16250"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/vox.13033"},{"issue":"7","key":"e_1_2_9_12_1","first-page":"1254","article-title":"Implementation of sexual risk behavior donor screening in Canada","volume":"64","author":"Goldman M","year":"2024","journal-title":"Transfus Clin Biol"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/trf.16753"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/tme.12888"},{"key":"e_1_2_9_15_1","unstructured":"Recommendations for Evaluating Donor Eligibility Using Individual Risk\u2010Based Questions To Reduce the Risk of Human Immunodeficiency Virus Transmission by Blood and Blood Products; Guidance for Industry; Availability [Internet]. Vol. 88 The Federal Register \/ FIND. Washington: Federal Information & News Dispatch LLC; p. 30765. Report No.: 0097\u20136326.2023. Available from:https:\/\/www.fda.gov\/regulatory\u2010information\/search\u2010fda\u2010guidance\u2010documents\/recommendations\u2010evaluating\u2010donor\u2010eligibility\u2010using\u2010individual\u2010risk\u2010based\u2010questions\u2010reduce\u2010risk\u2010human"},{"key":"e_1_2_9_16_1","volume-title":"Blood Donor Selection Policy: More People Now Able to Give Blood [Internet]","author":"NHS, Blood and Transplant","year":"2021"},{"issue":"3","key":"e_1_2_9_17_1","first-page":"441","article-title":"Changing blood donor screening criteria from permanent deferral for men who have sex with men to individual sexual risk assessment: no evidence of a significant impact on the human immunodeficiency virus epidemic in Italy","volume":"11","author":"Suligoil B","year":"2013","journal-title":"Blood Transfus"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/vox.12933"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1537-2995.2010.02804.x"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1537-2995.2011.03344.x"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/vox.13002"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/vox.12028"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/trf.17213"},{"key":"e_1_2_9_24_1","unstructured":"Epidemiological Report \u2013 HIV & AIDS 2023 [Internet]. 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