{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T15:05:12Z","timestamp":1789657512315,"version":"4.0.1"},"reference-count":33,"publisher":"Wiley","issue":"S1","license":[{"start":{"date-parts":[[2025,3,10]],"date-time":"2025-03-10T00:00:00Z","timestamp":1741564800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,3,10]],"date-time":"2025-03-10T00:00:00Z","timestamp":1741564800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Transfusion"],"published-print":{"date-parts":[[2025,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Resuscitative endovascular balloon occlusion of the aorta (REBOA) and emergency department thoracotomy (EDT) are effective methods of aortic occlusion (AO) for life\u2010threatening bleeding; however, complete AO can lead to visceral ischemia. Partial REBOA (P\u2010REBOA) has been proposed as an alternative to the completely occlusive REBOA (C\u2010REBOA) to balance hemorrhage control and perfusion. Using the Aortic Occlusion for Resuscitation in Trauma (AORTA) multicenter, observational registry, we tested the hypothesis that P\u2010REBOA resulted in better outcomes compared to EDT and C\u2010REBOA.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Study Design and Methods<\/jats:title>\n                    <jats:p>We queried the 2017\u20132023 AORTA registry for adults who underwent EDT, C\u2010REBOA, or P\u2010REBOA in the emergency department (ED). Patients with chest penetrating injuries were excluded. We compared mortality, ventilator\u2010free\u2010days (VFD), and ICU\u2010free\u2010days (ICUFD) using survival analysis or generalized linear models to adjust for confounders.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Overall, 921 patients underwent EDT (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u2009613, 66.6%), C\u2010REBOA (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u2009224, 24.3%), or P\u2010REBOA (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200984, 9.1%); 83.1% died. After confounder adjustment, compared to P\u2010REBOA, both C\u2010REBOA and EDT were associated with a lower likelihood of attaining hemodynamic improvement and stability as well as with higher mortality (adjusted hazard ratio, aHR\u2009=\u20091.84; 95% CI: 1.01\u20131.60 and aHR\u2009=\u20093.32; 95% CI: 1.96\u20132.78, respectively). EDT patients had less VFD and ICUFD than those undergoing C\u2010REBOA and P\u2010REBOA, but there were no differences between the two endovascular procedures. Among patients who survived &gt;48\u2009h, EDT was more likely to be associated with complications compared to the other two procedures.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>P\u2010REBOA was more likely to be associated with improved hemodynamic stability and reduced mortality compared to C\u2010REBOA and EDT, suggesting this modality may be a better AO procedure for patients with no penetrating thoracic injuries.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/trf.18177","type":"journal-article","created":{"date-parts":[[2025,3,11]],"date-time":"2025-03-11T20:58:36Z","timestamp":1741726716000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Partial REBOA Zone 1 is associated with lower mortality compared to complete REBOA Zone 1 and emergency department thoracotomy: A cohort study using the AORTA registry"],"prefix":"10.1111","volume":"65","author":[{"given":"Morgan G.","family":"Dewey","sequence":"first","affiliation":[{"name":"School of Medicine University of Colorado  Aurora Colorado USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ernest E.","family":"Moore","sequence":"additional","affiliation":[{"name":"School of Medicine University of Colorado  Aurora Colorado USA"},{"name":"Ernest E Moore Shock Trauma Center at Denver Health  Denver Colorado USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lee Anne","family":"Ammons","sequence":"additional","affiliation":[{"name":"Ernest E Moore Shock Trauma Center at Denver Health  Denver Colorado USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabella M.","family":"Bernhardt","sequence":"additional","affiliation":[{"name":"Department of Biological Sciences, Hunter College City University of New York  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8493-389X","authenticated-orcid":false,"given":"Angela","family":"Sauaia","sequence":"additional","affiliation":[{"name":"Sauaia Statistical Solutions, L.L.C  Denver Colorado USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meghan L.","family":"Brenner","sequence":"additional","affiliation":[{"name":"David Geffen School of Medicine, UCLA  Los Angeles California 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