{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T12:47:04Z","timestamp":1753879624522,"version":"3.41.2"},"reference-count":33,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2025,6,4]],"date-time":"2025-06-04T00:00:00Z","timestamp":1748995200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Transfusion"],"published-print":{"date-parts":[[2025,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Autologous blood donation (ABD) can be indicated in pregnant individuals with rare blood groups. Yet, unlike hospitals, some blood establishments are reluctant to collect ABDs in this population. Therefore, we evaluated the safety and use of prepartum ABD conducted by a blood establishment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design and Methods<\/jats:title><jats:p>This retrospective, descriptive cohort study used data from the ABD program in Qu\u00e9bec, Canada, and patient medical data reported by treating physicians. Patients were included if they were pregnant, enrolled in Qu\u00e9bec's ABD program between January 2010 and January 2021 (i.e., study period) and had a rare blood group.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Twenty\u2010four individuals met the inclusion criteria (mean age at first referral\u2009=\u200931.7\u2009years; 21 [87.5%] first\u2010time donors) and initiated 52 ABDs. Three mild vasovagal reactions (VVRs) were recorded, while no moderate or severe vasovagal reactions (VVRs) were observed. Of the 41\u2009units distributed to the hospitals' blood banks, none were transfused to the mother; 3 were transfused to the fetus or newborn. Most fresh unused units were salvaged and cryopreserved post\u2010delivery (75.0%). Twenty\u2010seven (51.9%) ABDs were made &lt;3\u2009weeks of the expected date of delivery. All seven individuals with available data on iron supplementation had iron deficiency, but only two (28.6%) received intravenous iron.<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion<\/jats:title><jats:p>ABDs may be safely carried out by a blood establishment among pregnant individuals. Transfusion rate is low; however, the majority of donated units are successfully recovered. Improvements will be made to the program by developing specific guidance to target iron deficiency management and timing of donation.<\/jats:p><\/jats:sec>","DOI":"10.1111\/trf.18288","type":"journal-article","created":{"date-parts":[[2025,6,4]],"date-time":"2025-06-04T12:04:32Z","timestamp":1749038672000},"page":"1264-1272","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Contemporary use and safety of prepartum autologous blood donation: A retrospective cohort study in Quebec, Canada"],"prefix":"10.1111","volume":"65","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1094-2811","authenticated-orcid":false,"given":"Catherine","family":"Dub\u00e9","sequence":"first","affiliation":[{"name":"Transfusion Medicine H\u00e9ma\u2010Qu\u00e9bec  Montr\u00e9al Quebec Canada"},{"name":"H\u00f4pital Charles\u2010Le Moyne Centre int\u00e9gr\u00e9 de sant\u00e9 et de services sociaux, Mont\u00e9r\u00e9gie\u2010Centre  Greenfield Park Quebec Canada"},{"name":"D\u00e9partement de m\u00e9decine, Facult\u00e9 de m\u00e9decine et des sciences de la sant\u00e9 Universit\u00e9 de Sherbrooke  Sherbrooke Quebec Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7675-3197","authenticated-orcid":false,"given":"Catherine","family":"Latour","sequence":"additional","affiliation":[{"name":"Transfusion Medicine H\u00e9ma\u2010Qu\u00e9bec  Montr\u00e9al Quebec Canada"},{"name":"H\u00f4pital Charles\u2010Le Moyne Centre int\u00e9gr\u00e9 de sant\u00e9 et de services sociaux, Mont\u00e9r\u00e9gie\u2010Centre  Greenfield Park Quebec Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jessica Constanzo","family":"Yanez","sequence":"additional","affiliation":[{"name":"Transfusion Medicine H\u00e9ma\u2010Qu\u00e9bec  Montr\u00e9al Quebec Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nancy","family":"Robitaille","sequence":"additional","affiliation":[{"name":"Transfusion Medicine H\u00e9ma\u2010Qu\u00e9bec  Montr\u00e9al Quebec Canada"},{"name":"Division of Hematology\u2010oncology, Department of Pediatrics CHU Sainte\u2010Justine  Quebec Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,6,4]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1537-2995.2002.00132.x"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1537-2995.2001.41121459.x"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tmrv.2015.04.001"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/vox.12867"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.2020007003"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.transci.2017.03.010"},{"issue":"2","key":"e_1_2_11_8_1","first-page":"CD003602","article-title":"Pre\u2010operative autologous donation for minimising perioperative allogeneic blood transfusion","volume":"2001","author":"Henry DA","year":"2002","journal-title":"Cochrane Database Syst Rev"},{"issue":"2","key":"e_1_2_11_9_1","first-page":"125","article-title":"Autologous blood in obstetrics: where are we going now?","volume":"10","author":"Liumbruno GM","year":"2012","journal-title":"Blood Transfus"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3148.2006.00696.x"},{"key":"e_1_2_11_11_1","unstructured":"National Advisory Committee on Blood and Blood Products.NAC Statement on Perioperative Autologous Blood Donation [Internet]. 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