{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T20:45:52Z","timestamp":1790455552060,"version":"4.1.0"},"reference-count":34,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2025,8,29]],"date-time":"2025-08-29T00:00:00Z","timestamp":1756425600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,8,29]],"date-time":"2025-08-29T00:00:00Z","timestamp":1756425600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Transfusion"],"published-print":{"date-parts":[[2025,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Prehospital blood transfusions are necessary in certain situations that involve significant bleeding to prevent fatality.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Study Design and Methods<\/jats:title>\n                    <jats:p>Members of the AABB Donor and Blood Component Management Prehospital working group collaborated to provide a consensus review of best practices in the implementation of a prehospital transfusion program.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Several logistic paradigms exist in terms of how blood products are provided to emergency medical services (EMS). Each paradigm has pros and cons and should be adopted according to the specific environmental and operational needs of the states, regions, and agencies they serve. Low titer group O whole blood (LTOWB) has been successfully used in prehospital programs, but blood components such as packed red blood cells (pRBCs) and liquid plasma may also be used. All blood products carried by EMS must be transported and stored according to the same regulatory requirements set by the United States Food and Drug Administration. Processes must be in place to minimize wastage of blood products carried by EMS due to product expiration to preserve this limited resource. Barriers to the implementation of a prehospital transfusion program include scope of practice limitations, program costs, blood product reimbursement, cost of wastage, and collaboration between prehospital agencies, blood suppliers, and hospital transfusion services.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>Program implementation requires significant collaboration among different business entities with a carefully written and executed agreement. Despite the barriers, prehospital transfusion programs are worthy endeavors with the potential to save lives.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/trf.18389","type":"journal-article","created":{"date-parts":[[2025,8,29]],"date-time":"2025-08-29T09:54:54Z","timestamp":1756461294000},"page":"1771-1779","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["How we implement a prehospital transfusion program"],"prefix":"10.1111","volume":"65","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7199-5821","authenticated-orcid":false,"given":"Emily","family":"Coberly","sequence":"first","affiliation":[{"name":"American Red Cross Biomedical Services  Washington District of Columbia USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Barry","sequence":"additional","affiliation":[{"name":"Independent Consultant  San Antonio Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8595-8856","authenticated-orcid":false,"given":"Bethany","family":"Brown","sequence":"additional","affiliation":[{"name":"American Red Cross Holland Lab for the Biomedical Sciences  Rockville Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tracy","family":"Cameron","sequence":"additional","affiliation":[{"name":"Ontario Regional Blood Coordinating Network The Ottawa Hospital Research Institute  Ottawa Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4377-8210","authenticated-orcid":false,"given":"Joyisa","family":"Deb","sequence":"additional","affiliation":[{"name":"All India Institute of Medical Sciences  Guwahati India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Justine","family":"Garza","sequence":"additional","affiliation":[{"name":"We Are Blood  Austin Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0961-0369","authenticated-orcid":false,"given":"Divjot Singh","family":"Lamba","sequence":"additional","affiliation":[{"name":"Department of Transfusion Medicine Post Graduate Institute of Medical Education and Research  Chandigarh India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Janine","family":"Shepherd","sequence":"additional","affiliation":[{"name":"Department of Laboratory and Pathology, Transfusion Services Denver Health and Hospital Authority  Denver Colorado USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erin","family":"Tuott","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine and Pathology University of Washington  Seattle Washington USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barbara","family":"Swanson","sequence":"additional","affiliation":[{"name":"DeGowin Blood Center University of Iowa HealthCare  Iowa City Iowa USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jed","family":"Gorlin","sequence":"additional","affiliation":[{"name":"Innovative Blood Resources Division of New York Blood Center, Physician Services  Saint Paul Minnesota USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7800-3119","authenticated-orcid":false,"given":"Yvette","family":"Tanhehco","sequence":"additional","affiliation":[{"name":"Department of Pathology and Cell Biology Columbia University Vagelos College of Physicians and Surgeons  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,8,29]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/TA.0000000000002833"},{"key":"e_1_2_13_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0000000000002999"},{"key":"e_1_2_13_4_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13049-023-01088-8"},{"key":"e_1_2_13_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00268-016-3572-4"},{"issue":"1","key":"e_1_2_13_6_1","first-page":"S80","article-title":"The regional whole blood program in San Antonio, TX: a 3\u2010year update on prehospital and in\u2010hospital transfusion practices for traumatic and non\u2010traumatic hemorrhage","volume":"62","author":"Braverman MA","year":"2022","journal-title":"Transfusion"},{"issue":"1","key":"e_1_2_13_7_1","first-page":"S15","article-title":"Prehospital whole blood reduces early mortality in patients with hemorrhagic shock","volume":"61","author":"Braverman MA","year":"2021","journal-title":"Transfusion"},{"key":"e_1_2_13_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/MOH.0000000000000386"},{"key":"e_1_2_13_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/emp2.13142"},{"key":"e_1_2_13_10_1","unstructured":"US Prehospital Blood Program Interactive Map. 2025 [cited 2025 May 21]. 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