{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,13]],"date-time":"2026-07-13T23:35:31Z","timestamp":1783985731254,"version":"3.55.0"},"reference-count":27,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2025,11,14]],"date-time":"2025-11-14T00:00:00Z","timestamp":1763078400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,11,14]],"date-time":"2025-11-14T00:00:00Z","timestamp":1763078400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Transfusion"],"published-print":{"date-parts":[[2025,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Billions live in blood deserts, regions where there is effectively no access to blood transfusions. Lodwar County Referral Hospital, set in a rural, low\u2010resource area in northwestern Kenya, is located in one such blood desert. A walking blood bank is a point\u2010of\u2010care system of emergency transfusion when banked blood is unavailable. The objective of this study was to evaluate the need, feasibility, and safety of a walking blood bank to address blood unavailability in a low\u2010resource, civilian setting.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Study Design and Methods<\/jats:title>\n                    <jats:p>This was a mixed\u2010methods study. Blood need was determined through chart review from April to July 2022. Feasibility was evaluated through qualitative interviews with hospital stakeholders. Safety was established by comparing the diagnostic performance of rapid diagnostic testing to standard\u2010of\u2010care assays for transfusion\u2010transmitted infections (HIV, HBV, HCV, syphilis).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Stockouts occurred 40 of 126\u2009days (32%). Stakeholders acknowledged blood was frequently unavailable and it was sometimes necessary to perform emergency transfusion using rapid tests to screen blood in order to save a life, despite uncertainty over their performance to detect transfusion infections. Overall transfusion infection prevalence in donors was 5.4%. Rapid testing had a 99.2% (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u2009.01) negative predictive value when compared against standard\u2010of\u2010care laboratory\u2010based tests.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>A walking blood bank for emergency transfusion that uses rapid diagnostic testing may serve as a feasible and safe\u00a0stopgap measure to address hemorrhagic shock and severe anemia in the world's blood deserts.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/trf.18460","type":"journal-article","created":{"date-parts":[[2025,11,14]],"date-time":"2025-11-14T14:11:28Z","timestamp":1763129488000},"page":"2293-2305","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["The local initiative for emergency blood (\n                    <scp>LIFE<\/scp>\n                    \u2010blood) study: A mixed\u2010methods, single\u2010center exploration of civilian walking blood bank need, feasibility, and safety in a low\u2010resource blood desert"],"prefix":"10.1111","volume":"65","author":[{"given":"Nakul","family":"Raykar","sequence":"first","affiliation":[{"name":"Department of Surgery Brigham and Women's Hospital  Boston Massachusetts USA"},{"name":"Program in Global Surgery and Social Change Harvard Medical School  Boston Massachusetts USA"},{"name":"Center for Surgery and Public Health Brigham and Women's Hospital  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tecla","family":"Chelagat","sequence":"additional","affiliation":[{"name":"Strathmore University  Nairobi Kenya"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5090-0328","authenticated-orcid":false,"given":"Linda 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