{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T03:12:15Z","timestamp":1789873935132,"version":"4.0.1"},"reference-count":17,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2026,4,21]],"date-time":"2026-04-21T00:00:00Z","timestamp":1776729600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,4,21]],"date-time":"2026-04-21T00:00:00Z","timestamp":1776729600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Transfusion"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>One mitigation strategy for donor iron deficiency is to implement ferritin testing and encourage donors with low ferritin to pause donation and increase iron intake. We evaluated positive outcomes (reduced hemoglobin deferrals) and negative outcomes (donor nonreturn) in a 2\u2010year observation period after implementing ferritin testing of female donors at each 10th donation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Donors with ferritin below 25 ug\/L were advised to pause donation for 6\u2009months and see their health care practitioner about increasing iron intake but were not deferred. Ferritin results for donors screened in the first 6\u2009months of the program (Jan\u2013June 2023), hemoglobin on return and time to return in the 2\u2009years following testing were calculated for low ferritin and normal\/high ferritin donors.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Twenty five percent of 8613 tested donors had low ferritin, associated with younger age, high donation frequency, and previous hemoglobin deferral. About one third of low ferritin donors returned to donate less than 6\u2009months after testing, and had a hemoglobin deferral rate of 16%, compared to 4.4% in those who waited 6\u2009months or more and 5.2% in donors with normal ferritin. After 2\u2009years, 77.5% of low ferritin compared to 88.5% of normal\/high ferritin donors returned to donate.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Iron deficiency was common. Low ferritin donors who paused donation and returned to donate had hemoglobin deferral rates similar to normal ferritin donors. However, many returned early and had high failure rates. Two years after testing, an 11% difference in return rates remained between low and normal\/high ferritin donors.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/trf.70236","type":"journal-article","created":{"date-parts":[[2026,4,22]],"date-time":"2026-04-22T05:03:51Z","timestamp":1776834231000},"page":"1358-1365","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Assessment of implementation of ferritin testing on donor return"],"prefix":"10.1111","volume":"66","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9904-9952","authenticated-orcid":false,"given":"Mindy","family":"Goldman","sequence":"first","affiliation":[{"name":"Canadian Blood Services  Ottawa Ontario Canada"},{"name":"Department of Pathology &amp; Laboratory Medicine University of Ottawa  Ottawa Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8472-9936","authenticated-orcid":false,"given":"Chinchin","family":"Wang","sequence":"additional","affiliation":[{"name":"Canadian Blood Services  Ottawa Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5585-6194","authenticated-orcid":false,"given":"Aditi","family":"Khandelwal","sequence":"additional","affiliation":[{"name":"Canadian Blood Services University of Toronto  Toronto Ontario Canada"},{"name":"Department of Laboratory Medicine &amp; Pathobiology University of Toronto  Toronto Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5332-2789","authenticated-orcid":false,"given":"Sheila F.","family":"O'Brien","sequence":"additional","affiliation":[{"name":"Canadian Blood Services  Ottawa Ontario Canada"},{"name":"School of Epidemiology and Public Health University of Ottawa  Ottawa Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,4,21]]},"reference":[{"key":"e_1_2_9_2_1","volume-title":"Blood donor health and safety","author":"Spencer BR","year":"2022"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/trf.13956"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tmrv.2013.11.001"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2017-019240"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/trf.15155"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/trf.16235"},{"key":"e_1_2_9_8_1","unstructured":"Australian Red Cross Lifeblood.Anaemia and iron deficiency in blood donors. Available from:https:\/\/www.lifeblood.com.au\/health\u2010professionals\/clinical\u2010practice\/clinical\u2010indications\/iron\u2010deficiency\u2010anaemia\/blood\u2010donors. Accessed 11 Feb 2026"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1537-2995.2011.03148.x"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(24)01085-7"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(24)01212-1"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tmrv.2024.150860"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/trf.17484"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/trf.13152"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/trf.14921"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/trf.12518"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/trf.12647"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/vox.13126"}],"container-title":["Transfusion"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/trf.70236","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/trf.70236","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/trf.70236","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T02:48:37Z","timestamp":1783651717000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/trf.70236"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4,21]]},"references-count":17,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2026,7]]}},"alternative-id":["10.1111\/trf.70236"],"URL":"https:\/\/doi.org\/10.1111\/trf.70236","archive":["Portico"],"relation":{},"ISSN":["0041-1132","1537-2995"],"issn-type":[{"value":"0041-1132","type":"print"},{"value":"1537-2995","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,4,21]]},"assertion":[{"value":"2026-02-26","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-04-12","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-04-21","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}