{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,2]],"date-time":"2026-11-02T01:27:44Z","timestamp":1793582864916,"version":"4.5.0"},"reference-count":20,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2026,4,23]],"date-time":"2026-04-23T00:00:00Z","timestamp":1776902400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,4,23]],"date-time":"2026-04-23T00:00:00Z","timestamp":1776902400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Transfusion"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>In 2022, Canadian Blood Services implemented a gender\u2010neutral sexual behavior\u2010based screening (SBBS) approach to donor deferral, replacing time\u2010based criteria targeting gay, bisexual and other men who have sex with men (gbMSM) and female partners of gbMSM. We assessed the impact of this policy change on human immunodeficiency virus (HIV), hepatitis C (HCV), and hepatitis B (HBV) prevalence, incidence, and residual risk.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Study Design and Methods<\/jats:title>\n                    <jats:p>We compared prevalence rates among first\u2010time donors, incidence rates, and residual risk for allogeneic donations made in the 3\u2009years pre\u2010SBBS implementation and 3\u2009years post\u2010SBBS implementation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>HIV and HBV prevalence remained steady while HCV prevalence increased among first\u2010time donors post SBSS\u2010implementation. Point estimates for incidence rates and residual risks decreased for each marker post\u2010implementation, but differences were not significant. Residual risks post\u2010implementation were 1 in 34.7 million for HIV, 1 in 64.1 million for HCV, and 1 in 3.1 million for HBV.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>Residual risks of infection remain low following the implementation of a gender\u2010neutral sexual risk behavior\u2010based approach to donor deferral. This policy change has not negatively impacted the safety of the Canadian blood supply.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/trf.70244","type":"journal-article","created":{"date-parts":[[2026,4,23]],"date-time":"2026-04-23T11:36:40Z","timestamp":1776944200000},"page":"1265-1270","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Residual risk of human immunodeficiency virus, hepatitis C, and hepatitis B following implementation of sexual risk behavior\u2010based screening in Canada"],"prefix":"10.1111","volume":"66","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8472-9936","authenticated-orcid":false,"given":"Chinchin","family":"Wang","sequence":"first","affiliation":[{"name":"Epidemiology and Surveillance Canadian Blood Services  Ottawa Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2519-1109","authenticated-orcid":false,"given":"Steven J.","family":"Drews","sequence":"additional","affiliation":[{"name":"Microbiology Canadian Blood Services  Ottawa Ontario Canada"},{"name":"Department of Laboratory Medicine and Pathology, Faculty of Medicine and Dentistry University of Alberta  Edmonton Alberta Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9904-9952","authenticated-orcid":false,"given":"Mindy","family":"Goldman","sequence":"additional","affiliation":[{"name":"Donation and Policy Studies Canadian Blood Services  Ottawa Ontario Canada"},{"name":"Department of Pathology and Laboratory Medicine University of Ottawa  Ottawa Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5332-2789","authenticated-orcid":false,"given":"Sheila F.","family":"O'Brien","sequence":"additional","affiliation":[{"name":"Epidemiology and Surveillance Canadian Blood Services  Ottawa Ontario Canada"},{"name":"School of Epidemiology and Public Health University of Ottawa  Ottawa Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,4,23]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/trf.17878"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/trf.16753"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.14745\/ccdr.v47i01a11"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.transci.2017.03.010"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1537-2995.2009.02195.x"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/trf.14457"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/trf.12592"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.3138\/canlivj.2018-0008"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.14745\/ccdr.v47i12a01"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12889-024-19790-2"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1537-2995.2007.01618.x"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.3390\/v16010117"},{"key":"e_1_2_8_14_1","first-page":"8","volume-title":"Abstracts 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